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Meeting Abstracts

835-P: The Hepatoselective Glucokinase Activator (GKA) TTP399 Does Not Increase Risk of Ketoacidosis in Type 1 Diabetes (T1D)

KLARA KLEIN, SCHAFER C. BOEDER, JENNIFER L. FREEMAN, SUPRADEEP MADDURI, ERIN R. GIOVANNETTI, CARMEN VALCARCE, JOHN B. BUSE, JEREMY PETTUS

Diabetes 2022;71(Supplement_1):835-P

DOI: https://doi.org/10.2337/db22-835-P

Published: 01 June 2022

View article titled, 835-P: The Hepatoselective Glucokinase Activator (GKA) TTP399 Does Not Increase Risk of Ketoacidosis in Type 1 Diabetes (T1D)

Meeting Abstracts

1334-P: Hepatocyte D-ß-Hydroxybutyrate Dehydrogenase Deficiency Improves Glucose Homeostasis and Prevents Diet-Induced Liver Fibrosis

DAVID B. STAGG, ALISHA R. SEAY, ALISA B. NELSON, DANA ANDRE A. D’AVIGNON, CURTIS C. HUGHEY, PATRYCJA PUCHALSKA, PETER A. CRAWFORD

Diabetes 2022;71(Supplement_1):1334-P

DOI: https://doi.org/10.2337/db22-1334-P

Published: 01 June 2022

View article titled, 1334-P: Hepatocyte D-ß-Hydroxybutyrate Dehydrogenase Deficiency Improves Glucose Homeostasis and Prevents Diet-Induced Liver Fibrosis

Meeting Abstracts

307-OR: Mean Blood Beta-Hydroxybutyrate Predicts Clinically Significant Weight Loss following 90 Days Carbohydrate-Restricted Nutrition Therapy

AMY L. MCKENZIE, SHAMINIE J. ATHINARAYANAN, REBECCA N. ADAMS, BRITTANIE M. VOLK, STEPHEN PHINNEY, ROBERT E. RATNER

Diabetes 2021;70(Supplement_1):307-OR

DOI: https://doi.org/10.2337/db21-307-OR

Published: 01 June 2021

View article titled, 307-OR: Mean Blood Beta-Hydroxybutyrate Predicts Clinically Significant Weight Loss following 90 Days Carbohydrate-Restricted Nutrition Therapy

Meeting Abstracts

962-P: Plasma Beta Hydroxybutyrate in Pregnancy and Gestational Diabetes

STEFANIE HINKLE, SAMRAWIT F. YISAHAK, SIFANG KATHY ZHAO, MICHAEL Y. TSAI, CUILIN ZHANG

Diabetes 2021;70(Supplement_1):962-P

DOI: https://doi.org/10.2337/db21-962-P

Published: 01 June 2021

View article titled, 962-P: Plasma Beta Hydroxybutyrate in Pregnancy and Gestational Diabetes

Meeting Abstracts

1133-P: Association of Higher Baseline BNP Levels with a Greater Reduction in Plasma Volume and Increase in Beta-Hydroxybutyrate via the SGLT2 Inhibitor Tofogliflozin in Type 2 Diabetes

AKIHIRO YOSHIDA, YASUHIRO MATSUBAYASHI, TOSHIAKI NOJIMA, HIDEKI SUGANAMI, MOMOKO OE, KAZUYA FUJIHARA, SHIRO TANAKA, KOHEI KAKU, HIROHITO SONE

Diabetes 2020;69(Supplement_1):1133-P

DOI: https://doi.org/10.2337/db20-1133-P

Published: 01 June 2020

View article titled, 1133-P: Association of Higher Baseline BNP Levels with a Greater Reduction in Plasma Volume and Increase in Beta-Hydroxybutyrate via the SGLT2 Inhibitor Tofogliflozin in Type 2 Diabetes

Meeting Abstracts

1129-P: Effect of Sotagliflozin Added to Insulin Therapy on Beta-Hydroxybutyrate in Patients with Type 1 Diabetes

ANNE L. PETERS, THOMAS DANNE, SANGEETA SAWHNEY, PHILLIP L. BANKS, MICHAEL J. DAVIES, PABLO LAPUERTA

Diabetes 2020;69(Supplement_1):1129-P

DOI: https://doi.org/10.2337/db20-1129-P

Published: 01 June 2020

View article titled, 1129-P: Effect of Sotagliflozin Added to Insulin Therapy on Beta-Hydroxybutyrate in Patients with Type 1 Diabetes

Meeting Abstracts

128-LB: Effects of Glucagon Receptor Antagonism (GRA) on Ketone Body Formation during Insulinopenia in Type 1 Diabetes (T1D)

SCHAFER C. BOEDER, DANIEL G. INES, LESLIE CARTER, ERIN R. GIOVANNETTI, DEBRA ARMSTRONG, PAIVI BURKE, JEREMY PETTUS

Diabetes 2020;69(Supplement_1):128-LB

DOI: https://doi.org/10.2337/db20-128-LB

Published: 01 June 2020

View article titled, 128-LB: Effects of Glucagon Receptor Antagonism (GRA) on Ketone Body Formation during Insulinopenia in Type 1 Diabetes (T1D)

Meeting Abstracts

1344-P: Metabolomics Reveals Broad Scale Metabolic Changes in Gestational Diabetes

YU LIU, ALAN KUANG, JAMES R. BAIN, TABITHA GEORGE, OLGA ILKAYEVA, ADAM MINCEY, MICHAEL MUEHLBAUER, LYNN P. LOWE, BOYD E. METZGER, CHRISTOPHER B. NEWGARD, DENISE SCHOLTENS, WILLIAM LOWE, JR.

Diabetes 2020;69(Supplement_1):1344-P

DOI: https://doi.org/10.2337/db20-1344-P

Published: 01 June 2020

View article titled, 1344-P: Metabolomics Reveals Broad Scale Metabolic Changes in Gestational Diabetes

Meeting Abstracts

2477-PUB: Blood Beta Hydroxybutyrate Levels in Adult Patients Presenting to Emergency Department

BARBARA DEPCZYNSKI, ALEXANDRA T. LEE, WAYNE F. VARNDELL, ANGELA L. CHIEW

Diabetes 2019;68(Supplement_1):2477-PUB

DOI: https://doi.org/10.2337/db19-2477-PUB

Published: 01 June 2019

View article titled, 2477-PUB: Blood Beta Hydroxybutyrate Levels in Adult Patients Presenting to Emergency Department

Meeting Abstracts

Initial Beta-Hydroxybutyrate Elevation in Relation to Subsequent Weight Loss in Type 2 Diabetes via the SGLT2 Inhibitor Tofogliflozin

YUICHI SATO, KIYOHIDE NUNOI, KOHEI KAKU, AKIHIRO YOSHIDA, HIDEKI SUGANAMI

Diabetes 2018;67(Supplement_1):1156-P

DOI: https://doi.org/10.2337/db18-1156-P

Published: 01 July 2018

View article titled, Initial Beta-Hydroxybutyrate Elevation in Relation to Subsequent Weight Loss in Type 2 Diabetes via the SGLT2 Inhibitor Tofogliflozin

Journal Articles

Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes

Ele Ferrannini, Simona Baldi, Silvia Frascerra, Brenno Astiarraga, Tim Heise, Roberto Bizzotto, Andrea Mari, Thomas R. Pieber, Elza Muscelli

Diabetes 2016;65(5):1190–1195

DOI: https://doi.org/10.2337/db15-1356

Published: 09 February 2016

View article titled, Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes

Includes: Supplementary data

Journal Articles

Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia

Kathleen A. Page, Anne Williamson, Namyi Yu, Ewan C. McNay, James Dzuira, Rory J. McCrimmon, Robert S. Sherwin

Diabetes 2009;58(5):1237–1244

DOI: https://doi.org/10.2337/db08-1557

Published: 17 February 2009

View article titled, Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia

Journal Articles

β-Hydroxybutyrate Increases Reactive Oxygen Species in Late but Not in Early Postimplantation Embryonic Cells In Vitro

Henrik Forsberg, Ulf J Eriksson, Öjar Melefors, Nils Welsh

Diabetes 1998;47(2):255–262

DOI: https://doi.org/10.2337/diab.47.2.255

Published: 01 February 1998

View article titled, β-Hydroxybutyrate Increases Reactive Oxygen Species in Late but Not in Early Postimplantation Embryonic Cells In Vitro

Journal Articles

Long-Term Prospective Evaluation of Offspring of Diabetic Mothers

Bernard L Silverman, Thomas Rizzo, Orville C Green, Nam H Cho, Robert J Winter, Edward S Ogata, Gail E Richards, Boyd E Metzger

Diabetes 1991;40(Supplement_2):121–125

DOI: https://doi.org/10.2337/diab.40.2.S121

Published: 01 December 1991

View article titled, Long-Term Prospective Evaluation of Offspring of Diabetic Mothers

Journal Articles

Release of Amylin From Perfused Rat Pancreas in Response to Glucose, Arginine, β-Hydroxybutyrate, and Gliclazide

Kaoru Inoue, Akitaka Hisatomi, Fumio Umeda, Hajime Nawata

Diabetes 1991;40(8):1005–1009

DOI: https://doi.org/10.2337/diab.40.8.1005

Published: 01 August 1991

View article titled, Release of Amylin From Perfused Rat Pancreas in Response to Glucose, Arginine, β-Hydroxybutyrate, and Gliclazide

Journal Articles

Nutritional and Hormonal Regulation of Articular Collagen Production in Diabetic Animals

Guillermo E Umpierrez, Steven Goldstein, Lawrence S Phillips, Robert G Spanheimer

Diabetes 1989;38(6):758–763

DOI: https://doi.org/10.2337/diab.38.6.758

Published: 01 June 1989

View article titled, Nutritional and Hormonal Regulation of Articular Collagen Production in Diabetic Animals

Journal Articles

Evidence for Multifactorial Origin of Diabetes-Induced Embryopathies

T W Sadler, E S Hunter, III, R E Wynn, L S Phillips

Diabetes 1989;38(1):70–74

DOI: https://doi.org/10.2337/diab.38.1.70

Published: 01 January 1989

View article titled, Evidence for Multifactorial Origin of Diabetes-Induced Embryopathies

Journal Articles

β-Hydroxybutyrate Increases the Insulin Sensitivity of Adipocyte Glucose Transport at a Postreceptor Level

Allan Green, Dalia P Bustillos, Robert I Misbin

Diabetes 1984;33(11):1045–1050

DOI: https://doi.org/10.2337/diab.33.11.1045

Published: 01 November 1984

View article titled, β-Hydroxybutyrate Increases the Insulin Sensitivity of Adipocyte Glucose Transport at a Postreceptor Level

Journal Articles

Effects of Maternal Diabetes on Early Embryogenesis: Alterations in Morphogenesis Produced by the Ketone Body, B-Hydroxybutyrate

W E Horton, Jr, T W Sadler

Diabetes 1983;32(7):610–616

DOI: https://doi.org/10.2337/diab.32.7.610

Published: 01 July 1983

View article titled, Effects of Maternal Diabetes on Early Embryogenesis: Alterations in Morphogenesis Produced by the Ketone Body, B-Hydroxybutyrate

Journal Articles

Failure of Infused β-Hydroxybutyrate to Decrease Proteolysis in Man

John M Miles, Steven L Nissen, Robert A Rizza, John E Gerich, Morey W Haymond

Diabetes 1983;32(3):197–205

DOI: https://doi.org/10.2337/diab.32.3.197

Published: 01 March 1983

View article titled, Failure of Infused β-Hydroxybutyrate to Decrease Proteolysis in Man

NARROW

835-P: The Hepatoselective Glucokinase Activator (GKA) TTP399 Does Not Increase Risk of Ketoacidosis in Type 1 Diabetes (T1D)

1334-P: Hepatocyte D-ß-Hydroxybutyrate Dehydrogenase Deficiency Improves Glucose Homeostasis and Prevents Diet-Induced Liver Fibrosis

307-OR: Mean Blood Beta-Hydroxybutyrate Predicts Clinically Significant Weight Loss following 90 Days Carbohydrate-Restricted Nutrition Therapy

962-P: Plasma Beta Hydroxybutyrate in Pregnancy and Gestational Diabetes

1133-P: Association of Higher Baseline BNP Levels with a Greater Reduction in Plasma Volume and Increase in Beta-Hydroxybutyrate via the SGLT2 Inhibitor Tofogliflozin in Type 2 Diabetes

1129-P: Effect of Sotagliflozin Added to Insulin Therapy on Beta-Hydroxybutyrate in Patients with Type 1 Diabetes

128-LB: Effects of Glucagon Receptor Antagonism (GRA) on Ketone Body Formation during Insulinopenia in Type 1 Diabetes (T1D)

1344-P: Metabolomics Reveals Broad Scale Metabolic Changes in Gestational Diabetes

2477-PUB: Blood Beta Hydroxybutyrate Levels in Adult Patients Presenting to Emergency Department

Initial Beta-Hydroxybutyrate Elevation in Relation to Subsequent Weight Loss in Type 2 Diabetes via the SGLT2 Inhibitor Tofogliflozin

Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes

Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia

β-Hydroxybutyrate Increases Reactive Oxygen Species in Late but Not in Early Postimplantation Embryonic Cells In Vitro

Long-Term Prospective Evaluation of Offspring of Diabetic Mothers

Release of Amylin From Perfused Rat Pancreas in Response to Glucose, Arginine, β-Hydroxybutyrate, and Gliclazide

Nutritional and Hormonal Regulation of Articular Collagen Production in Diabetic Animals

Evidence for Multifactorial Origin of Diabetes-Induced Embryopathies

β-Hydroxybutyrate Increases the Insulin Sensitivity of Adipocyte Glucose Transport at a Postreceptor Level

Effects of Maternal Diabetes on Early Embryogenesis: Alterations in Morphogenesis Produced by the Ketone Body, B-Hydroxybutyrate

Failure of Infused β-Hydroxybutyrate to Decrease Proteolysis in Man

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