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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(9):1177–1178

https://doi.org/10.2337/db23-ti09

Published: 21 August 2023

View article titled, In This Issue of <em>Diabetes</em>

Journal Articles

Unveiling Novel Markers and Modeling Clinical Prediction of Treatment Effects Are Equally Important for Implementing Precision Therapeutics

Vincenzo Trischitta, Claudia Menzaghi, Massimiliano Copetti

Diabetes 2023;72(8):1057–1059

https://doi.org/10.2337/dbi22-0039

Published: 20 July 2023

View article titled, Unveiling Novel Markers and Modeling Clinical Prediction of Treatment Effects Are Equally Important for Implementing Precision Therapeutics

Journal Articles

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

Yi-Chun Chen, Austin J. Taylor, James M. Fulcher, Adam C. Swensen, Xiao-Qing Dai, Mitsuhiro Komba, Kenzie L.C. Wrightson, Kenny Fok, Annette E. Patterson, Ramon I. Klein Geltink, Patrick E. MacDonald, Wei-Jun Qian, C. Bruce Verchere

Diabetes 2023;72(9):1277–1288

https://doi.org/10.2337/db22-0945

Published: 26 June 2023

View article titled, Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

Meeting Abstracts

1822-PUB: Identifying the Link between In-Hospital Hyperglycemia and Outcomes among Persons Admitted with a Severe Infection

JULIA J. BAKKER, AMARENS VAN DER VAART, HJALMAR BOUMA, PRATIK CHOUDHARY, PR VAN DIJK

Diabetes 2023;72(Supplement_1):1822-PUB

https://doi.org/10.2337/db23-1822-PUB

Published: 23 June 2023

View article titled, 1822-PUB: Identifying the Link between In-Hospital Hyperglycemia and Outcomes among Persons Admitted with a Severe Infection

Journal Articles

A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice

Anna L. Lang, Nadee Nissanka, Ruy A. Louzada, Alejandro Tamayo, Elizabeth Pereira, Carlos T. Moraes, Alejandro Caicedo

Diabetes 2023;72(9):1262–1276

https://doi.org/10.2337/db22-0728

Published: 21 June 2023

View article titled, A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice

Meeting Abstracts

196-LB: Heterogeneity in Elevated Glucose and A1C as Predictors of the Prediabetes-to-Diabetes Transition—Framingham Heart Study, Multiethnic Study on Atherosclerosis, Jackson Heart Study, and Atherosclerosis Risk In Communities

CHIRAG PATEL

Diabetes 2023;72(Supplement_1):196-LB

https://doi.org/10.2337/db23-196-LB

Published: 20 June 2023

View article titled, 196-LB: Heterogeneity in Elevated Glucose and A1C as Predictors of the Prediabetes-to-Diabetes Transition—Framingham Heart Study, Multiethnic Study on Atherosclerosis, Jackson Heart Study, and Atherosclerosis Risk In Communities

Meeting Abstracts

480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

WATARU NIHEI, AYAKO KATO, TATSUHITO HIMENO, MASAKI KONDO, JIRO NAKAMURA, HIDEKI KAMIYA, KAZUNORI SANGO, KOICHI KATO

Diabetes 2023;72(Supplement_1):480-P

https://doi.org/10.2337/db23-480-P

Published: 20 June 2023

View article titled, 480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

Meeting Abstracts

100-LB: Dapagliflozin for Inpatient Hyperglycemia in Cardiac Surgery Patients with Type 2 Diabetes—Randomized Controlled Trial

MOHAMMAD S. KUCHAY, PUSHPENDER KHATANA, MITALI MISHRA, PARVATHI S, PARJEET KAUR, JASJEET S. WASIR, HARMANDEEP KAUR, APANSHU SINGH, RUJUL JAIN, CHHAVI KOHLI, GAZAL BAKSHI, VISHNUPRIYA RADHIKA, SUMAYYA SAHEER, MANISH K. SINGH, SUNIL MISHRA

Diabetes 2023;72(Supplement_1):100-LB

https://doi.org/10.2337/db23-100-LB

Published: 20 June 2023

View article titled, 100-LB: Dapagliflozin for Inpatient Hyperglycemia in Cardiac Surgery Patients with Type 2 Diabetes—Randomized Controlled Trial

Meeting Abstracts

337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

DAVIDE ROMERES, YOGESH YADAV, FNU RUCHI, RICKEY CARTER, CLAUDIO COBELLI, RITA BASU, ANANDA BASU

Diabetes 2023;72(Supplement_1):337-OR

https://doi.org/10.2337/db23-337-OR

Published: 20 June 2023

View article titled, 337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

Meeting Abstracts

152-LB: Implementing a Pilot Clinic for Steroid-Induced Hyperglycemia in Graft vs. Host Disease

DANIEL PHAM, KRISTINE GRDINOVAC, JORDAN LEAL, LIZA RODRIGUEZ, ALEXIS SALVA, WILLIAM WESSON, JOSEPH MCGUIRK

Diabetes 2023;72(Supplement_1):152-LB

https://doi.org/10.2337/db23-152-LB

Published: 20 June 2023

View article titled, 152-LB: Implementing a Pilot Clinic for Steroid-Induced Hyperglycemia in Graft vs. Host Disease

Meeting Abstracts

26-OR: A Novel Drug That Normalizes Hyperglycemia in Type 1 Diabetes

FARZAD ASADI, SUBHADRA C. GUNAWARDANA, DAVID W. PISTON

Diabetes 2023;72(Supplement_1):26-OR

https://doi.org/10.2337/db23-26-OR

Published: 20 June 2023

View article titled, 26-OR: A Novel Drug That Normalizes Hyperglycemia in Type 1 Diabetes

Meeting Abstracts

171-OR: Diagnosing GDM in Pregnancy—Closing the Door after the Horse Has Bolted?

CHITTARANJAN S. YAJNIK, SOUVIK BANDYOPADHYAY, ABOLI A. BHALERAO, DATTATREY BHAT, SANAT PHATAK, RUCHA H. WAGH, PALLAVI C. YAJNIK, SUHAS R. OTIV, KURUS J. COYAJI, CAROLINE FALL

Diabetes 2023;72(Supplement_1):171-OR

https://doi.org/10.2337/db23-171-OR

Published: 20 June 2023

View article titled, 171-OR: Diagnosing GDM in Pregnancy—Closing the Door after the Horse Has Bolted?

Meeting Abstracts

1420-P: Predictors of Readmission and Mortality in Adults with Diabetes or Stress Hyperglycemia after Initial Hospitalization for COVID-19

AKSHATA S. CHAUGULE, KYRA HOWARD, DONALD C. SIMONSON, MARIE E. MCDONNELL, RAJESH K. GARG, GEETHA GOPALAKRISHNAN, JOANNA MITRI, JASMIN LEBASTCHI, NADINE E. PALERMO, GREGORY P. WESTCOTT, RUTH S. WEINSTOCK

Diabetes 2023;72(Supplement_1):1420-P

https://doi.org/10.2337/db23-1420-P

Published: 20 June 2023

View article titled, 1420-P: Predictors of Readmission and Mortality in Adults with Diabetes or Stress Hyperglycemia after Initial Hospitalization for COVID-19

Meeting Abstracts

278-OR: Impact of a Parameter Change in DBLG1 System

ALICE ADENIS, AURÉLIEN VESIN, HECTOR M. ROMERO-UGALDE, MAXIME LOUIS, CLÉMENT V. HUBER, LIM-SYLVIE POU, YOUSRA TOURKI, ERIK HUNEKER, PIERRE Y. BENHAMOU

Diabetes 2023;72(Supplement_1):278-OR

https://doi.org/10.2337/db23-278-OR

Published: 20 June 2023

View article titled, 278-OR: Impact of a Parameter Change in DBLG1 System

Meeting Abstracts

1467-P: Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients without Diabetes

AARON J. DEUTSCH, PHILIP H. SCHROEDER, RAVI MANDLA, FEYZA ERENLER, JOSEP M. MERCADER, MIRIAM UDLER, JOSE C. FLOREZ, LAURA BRENNER

Diabetes 2023;72(Supplement_1):1467-P

https://doi.org/10.2337/db23-1467-P

Published: 20 June 2023

View article titled, 1467-P: Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients without Diabetes

Meeting Abstracts

178-LB: Association of Pregnancy Oral Glucose Tolerance Test (OGTT) Glucose Response with Metabolic Profile in Mother and Child—Hyperglycemia and Adverse Pregnancy Outcomes Follow-up Study (HAPO-FUS)

VIDHU V. THAKER, CHARLES A. LEDUC, RANY SALEM

Diabetes 2023;72(Supplement_1):178-LB

https://doi.org/10.2337/db23-178-LB

Published: 20 June 2023

View article titled, 178-LB: Association of Pregnancy Oral Glucose Tolerance Test (OGTT) Glucose Response with Metabolic Profile in Mother and Child—Hyperglycemia and Adverse Pregnancy Outcomes Follow-up Study (HAPO-FUS)

Meeting Abstracts

253-LB: Characterization of Korean Type 2 Diabetes as Hyperinsulinemic, Insulin-Resistant, and miR-10a/b-5p-Deficient Hyperglycemia

TAE YANG YU, MIN-SEOB KIM, SE EUN HA, RAJAN SINGH, DAHYUN SEON, JIN WOO JEONG, MOON YOUNG LEE, SEUNGIL RO

Diabetes 2023;72(Supplement_1):253-LB

https://doi.org/10.2337/db23-253-LB

Published: 20 June 2023

View article titled, 253-LB: Characterization of Korean Type 2 Diabetes as Hyperinsulinemic, Insulin-Resistant, and miR-10a/b-5p-Deficient Hyperglycemia

Meeting Abstracts

154-OR: Metabolomics Analysis Reveals Links between Stress Hyperglycemia and Underlying Differences in Branched-Chain Amino-Acid Metabolism and Microbiome–Host Interactions

AMALIA ABRAHAM, MATTHEW R. SMITH, MIREYA PEREZ-GUZMAN, FARBOD ZAHEDI TAJRISHI, LIZDA I. GUERRERO ARROYO, AMSHUMANTH CHAKRAGIRI, JITHIN SAM VARGHESE, FRANCISCO J. PASQUEL

Diabetes 2023;72(Supplement_1):154-OR

https://doi.org/10.2337/db23-154-OR

Published: 20 June 2023

View article titled, 154-OR: Metabolomics Analysis Reveals Links between Stress Hyperglycemia and Underlying Differences in Branched-Chain Amino-Acid Metabolism and Microbiome–Host Interactions

Meeting Abstracts

247-LB: Link between Hyperglycemia and Cognitive Deficits in T2DM Animal Model

LI CHEN, JIANGXIA NI, LINGGE FENG, XUEXIN ZHANG, QIUYAN WANG, YELIN CHEN

Diabetes 2023;72(Supplement_1):247-LB

https://doi.org/10.2337/db23-247-LB

Published: 20 June 2023

View article titled, 247-LB: Link between Hyperglycemia and Cognitive Deficits in T2DM Animal Model

Meeting Abstracts

1563-P: Hepatic PHD3 Stimulates Gluconeogenesis and Aggravates Hyperglycemia and Type 2 Diabetes by Hydroxylating CRTC2 at Pro129 and Pro615

YAQIAN XUE, AOYUAN CUI, SHUANG WEI, FENGGUANG MA, ZHENGSHUAI LIU, XIA FANG, WENJING LI, YUXIAO LIU, GENXIANG CAI, WEITONG SU, JIUXIANG ZHAO, CHENLIN GAO, JIAN WEN, YONG XU, WENGUANG FU, JING C. FANG, YU LI

Diabetes 2023;72(Supplement_1):1563-P

https://doi.org/10.2337/db23-1563-P

Published: 20 June 2023

View article titled, 1563-P: Hepatic PHD3 Stimulates Gluconeogenesis and Aggravates Hyperglycemia and Type 2 Diabetes by Hydroxylating CRTC2 at Pro129 and Pro615

NARROW

In This Issue of Diabetes

Unveiling Novel Markers and Modeling Clinical Prediction of Treatment Effects Are Equally Important for Implementing Precision Therapeutics

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

1822-PUB: Identifying the Link between In-Hospital Hyperglycemia and Outcomes among Persons Admitted with a Severe Infection

A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice

196-LB: Heterogeneity in Elevated Glucose and A1C as Predictors of the Prediabetes-to-Diabetes Transition—Framingham Heart Study, Multiethnic Study on Atherosclerosis, Jackson Heart Study, and Atherosclerosis Risk In Communities

480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

100-LB: Dapagliflozin for Inpatient Hyperglycemia in Cardiac Surgery Patients with Type 2 Diabetes—Randomized Controlled Trial

337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

152-LB: Implementing a Pilot Clinic for Steroid-Induced Hyperglycemia in Graft vs. Host Disease

26-OR: A Novel Drug That Normalizes Hyperglycemia in Type 1 Diabetes

171-OR: Diagnosing GDM in Pregnancy—Closing the Door after the Horse Has Bolted?

1420-P: Predictors of Readmission and Mortality in Adults with Diabetes or Stress Hyperglycemia after Initial Hospitalization for COVID-19

278-OR: Impact of a Parameter Change in DBLG1 System

1467-P: Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients without Diabetes

178-LB: Association of Pregnancy Oral Glucose Tolerance Test (OGTT) Glucose Response with Metabolic Profile in Mother and Child—Hyperglycemia and Adverse Pregnancy Outcomes Follow-up Study (HAPO-FUS)

253-LB: Characterization of Korean Type 2 Diabetes as Hyperinsulinemic, Insulin-Resistant, and miR-10a/b-5p-Deficient Hyperglycemia

154-OR: Metabolomics Analysis Reveals Links between Stress Hyperglycemia and Underlying Differences in Branched-Chain Amino-Acid Metabolism and Microbiome–Host Interactions

247-LB: Link between Hyperglycemia and Cognitive Deficits in T2DM Animal Model

1563-P: Hepatic PHD3 Stimulates Gluconeogenesis and Aggravates Hyperglycemia and Type 2 Diabetes by Hydroxylating CRTC2 at Pro129 and Pro615

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