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Journal Articles

MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis

Junhee Park, Catherine Hall, Brandon Hubbard, Traci LaMoia, Rafael Gaspar, Ali Nasiri, Fang Li, Hanrui Zhang, Jiyeon Kim, Rebecca A. Haeusler, Domenico Accili, Gerald I. Shulman, Hongtao Yu, Eunhee Choi1

Diabetes db230314

https://doi.org/10.2337/db23-0314

Published: 19 September 2023

View article titled, MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis

Meeting Abstracts

1741-P: Placental Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Regulate Offspring Glucose Homeostasis and Insulin Sensitivity

MEGAN BEETCH, EMILYN ALEJANDRO

Diabetes 2023;72(Supplement_1):1741-P

https://doi.org/10.2337/db23-1741-P

Published: 20 June 2023

View article titled, 1741-P: Placental Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Regulate Offspring Glucose Homeostasis and Insulin Sensitivity

Meeting Abstracts

291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

YANMEI QI, JIE LIU, JOSHUA C. CHAO, SAUM A. RAHIMI, LEONARD Y. LEE, SHAOHUA LI

Diabetes 2023;72(Supplement_1):291-OR

https://doi.org/10.2337/db23-291-OR

Published: 20 June 2023

View article titled, 291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

Journal Articles

Placing a Hex on Glucose Uptake

Faith M. Bowman, Scott A. Summers, William L. Holland

Diabetes 2023;72(6):690–692

https://doi.org/10.2337/dbi22-0040

Published: 19 May 2023

View article titled, Placing a Hex on Glucose Uptake

Journal Articles

Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction

Huan Chen, Ali Wu, Mark L. Zeidel, Weiqun Yu

Diabetes 2022;71(10):2197–2208

https://doi.org/10.2337/db22-0233

Published: 25 July 2022

View article titled, Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction

Journal Articles

Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice

Teayoun Kim, Shelly Nason, Jessica Antipenko, Brian Finan, Anath Shalev, Richard DiMarchi, Kirk M. Habegger

Diabetes 2022;71(10):2123–2135

https://doi.org/10.2337/db21-1018

Published: 25 July 2022

View article titled, Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice

Journal Articles

Cross Talk Between Insulin and Glucagon Receptor Signaling in the Hepatocyte

Kirk M. Habegger

Diabetes 2022;71(9):1842–1851

https://doi.org/10.2337/dbi22-0002

Published: 03 June 2022

View article titled, Cross Talk Between Insulin and Glucagon Receptor Signaling in the Hepatocyte

Meeting Abstracts

411-P: Potential to Utilize DNA Methylation as a Biomarker to Predict Major Coronary Artery Disease (CAD) Risk in Type 1 Diabetes (T1D)

RACHEL G. MILLER, JOSYF MYCHALECKYJ, SUNA ONENGUT-GUMUSCU, TREVOR J. ORCHARD, TINA COSTACOU

Diabetes 2022;71(Supplement_1):411-P

https://doi.org/10.2337/db22-411-P

Published: 01 June 2022

View article titled, 411-P: Potential to Utilize DNA Methylation as a Biomarker to Predict Major Coronary Artery Disease (CAD) Risk in Type 1 Diabetes (T1D)

Meeting Abstracts

1305-P: Insulin Receptor Condensates in Insulin Sensitivity and Resistance

ALESSANDRA DALL’AGNESE, JESSE PLATT, TONG IHN LEE, JACOB F. JEPPESEN, RICHARD A. YOUNG

Diabetes 2022;71(Supplement_1):1305-P

https://doi.org/10.2337/db22-1305-P

Published: 01 June 2022

View article titled, 1305-P: Insulin Receptor Condensates in Insulin Sensitivity and Resistance

Meeting Abstracts

1320-P: Insulin Receptors and Their Signal Transduction Pathways in Choroid Plexus

CAIO MAZUCANTI, VERNON L. KENNEDY, ANDREW CHO, QING-RONG LIU, JENNIFER F. O’CONNELL, SIMONETTA CAMANDOLA, JOSEPHINE M. EGAN

Diabetes 2022;71(Supplement_1):1320-P

https://doi.org/10.2337/db22-1320-P

Published: 01 June 2022

View article titled, 1320-P: Insulin Receptors and Their Signal Transduction Pathways in Choroid Plexus

Meeting Abstracts

1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

QIAN LI, JIALIN FU, KYOUNGMIN PARK, QIN LI, GEORGE L. KING

Diabetes 2022;71(Supplement_1):1482-PUB

https://doi.org/10.2337/db22-1482-PUB

Published: 01 June 2022

View article titled, 1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

Meeting Abstracts

223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

HIROFUMI NAGAO, WEIKANG CAI, HUI PAN, THIAGO M. BATISTA, BRUNA BRANDAO, C. RONALD KAHN

Diabetes 2022;71(Supplement_1):223-OR

https://doi.org/10.2337/db22-223-OR

Published: 01 June 2022

View article titled, 223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

Meeting Abstracts

1468-P: Effect of Kcnq1ot1 on Influencing the Function of Pancreatic ß-Cells Targeting miR-92a-1-5p

YALAN CHEN, YANLI LI, WEN XU, BEISI LIN, XIAODONG MAI, YUEYUE PENG, DANRUI CHEN, YANNA SU, WANGEN LI

Diabetes 2022;71(Supplement_1):1468-P

https://doi.org/10.2337/db22-1468-P

Published: 01 June 2022

View article titled, 1468-P: Effect of Kcnq1ot1 on Influencing the Function of Pancreatic ß-Cells Targeting miR-92a-1-5p

Journal Articles

Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Inga Kavazović, Mia Krapić, Ammarina Beumer-Chuwonpad, Bojan Polić, Tamara Turk Wensveen, Niels A. Lemmermann, Klaas P.J.M. van Gisbergen, Felix M. Wensveen

Diabetes 2022;71(4):706–721

https://doi.org/10.2337/db21-0209

Published: 19 January 2022

View article titled, Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Journal Articles

Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target

María Garranzo-Asensio, Guillermo Solís-Fernández, Ana Montero-Calle, José Manuel García-Martínez, Maria Carmen Fiuza, Pilar Pallares, Nuria Palacios-Garcia, Custodia García-Jiménez, Ana Guzman-Aranguez, Rodrigo Barderas

Diabetes 2022;71(3):497–510

https://doi.org/10.2337/db20-1206

Published: 18 January 2022

View article titled, Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target

Journal Articles

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

Gabriela Farias Quipildor, Kai Mao, Pedro J. Beltran, Nir Barzilai, Derek M. Huffman

Diabetes 2021;70(10):2237–2249

https://doi.org/10.2337/db21-0028

Published: 20 July 2021

View article titled, Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

Meeting Abstracts

337-OR: Intensive Insulin Treatment in a Patient with Type A Insulin Resistance Syndrome Associated with a Novel Heterozygous Mutation of Trp1120Gly in the Insulin Receptor Gene

YU YANG, ZHIMIN HUANG, GUOHONG WEI, YUELI LI, WANPING DENG, YANBING LI

Diabetes 2021;70(Supplement_1):337-OR

https://doi.org/10.2337/db21-337-OR

Published: 01 June 2021

View article titled, 337-OR: Intensive Insulin Treatment in a Patient with Type A Insulin Resistance Syndrome Associated with a Novel Heterozygous Mutation of Trp1120Gly in the Insulin Receptor Gene

Meeting Abstracts

55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

QIAN LI, JIALIN FU, KYOUNGMIN PARK, I-HSIEN WU, GEORGE L. KING

Diabetes 2021;70(Supplement_1):55-OR

https://doi.org/10.2337/db21-55-OR

Published: 01 June 2021

View article titled, 55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

Journal Articles

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Jun Hosoe, Yuki Kawashima-Sonoyama, Fuyuki Miya, Hiroko Kadowaki, Ken Suzuki, Takashi Kato, Fumiko Matsuzawa, Sei-Ichi Aikawa, Yukinori Okada, Tatsuhiko Tsunoda, Keiichi Hanaki, Susumu Kanzaki, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki

Diabetes 2021;70(8):1874–1884

https://doi.org/10.2337/db20-1145

Published: 01 June 2021

View article titled, Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Journal Articles

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Takanori Hayashi, Tetsuya Kubota, Inoue Mariko, Iseki Takamoto, Masakazu Aihara, Yoshitaka Sakurai, Nobuhiro Wada, Takashi Miki, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki

Diabetes 2021;70(8):1640–1653

https://doi.org/10.2337/db20-0482

Published: 12 May 2021

View article titled, Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

NARROW

MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis

1741-P: Placental Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Regulate Offspring Glucose Homeostasis and Insulin Sensitivity

291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

Placing a Hex on Glucose Uptake

Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction

Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice

Cross Talk Between Insulin and Glucagon Receptor Signaling in the Hepatocyte

411-P: Potential to Utilize DNA Methylation as a Biomarker to Predict Major Coronary Artery Disease (CAD) Risk in Type 1 Diabetes (T1D)

1305-P: Insulin Receptor Condensates in Insulin Sensitivity and Resistance

1320-P: Insulin Receptors and Their Signal Transduction Pathways in Choroid Plexus

1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

1468-P: Effect of Kcnq1ot1 on Influencing the Function of Pancreatic ß-Cells Targeting miR-92a-1-5p

Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

337-OR: Intensive Insulin Treatment in a Patient with Type A Insulin Resistance Syndrome Associated with a Novel Heterozygous Mutation of Trp1120Gly in the Insulin Receptor Gene

55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

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