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Journal Articles

Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle

Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, Matthew J. Watt

Diabetes 2023;72(6):715–727

DOI: https://doi.org/10.2337/db22-0590

Published: 29 December 2022

View article titled, Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle

Meeting Abstracts

97-LB: The DERMIS Study—Preliminary Evaluation of Skin Changes at Continuous Subcutaneous Insulin Infusion (CSII) Sites in Type 1 Diabetes (T1D)

JESICA D. BARAN, DORI KHAKPOUR, ANDREA KALUS, MICHI SHINOHARA, XIAOFU DONG, DANIEL S. HIPPE, IRL B. HIRSCH

Diabetes 2022;71(Supplement_1):97-LB

DOI: https://doi.org/10.2337/db22-97-LB

Published: 01 June 2022

View article titled, 97-LB: The DERMIS Study—Preliminary Evaluation of Skin Changes at Continuous Subcutaneous Insulin Infusion (CSII) Sites in Type 1 Diabetes (T1D)

Journal Articles

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

Gabriela Farias Quipildor, Kai Mao, Pedro J. Beltran, Nir Barzilai, Derek M. Huffman

Diabetes 2021;70(10):2237–2249

DOI: https://doi.org/10.2337/db21-0028

Published: 20 July 2021

View article titled, Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

Journal Articles

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Takanori Hayashi, Tetsuya Kubota, Inoue Mariko, Iseki Takamoto, Masakazu Aihara, Yoshitaka Sakurai, Nobuhiro Wada, Takashi Miki, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki

Diabetes 2021;70(8):1640–1653

DOI: https://doi.org/10.2337/db20-0482

Published: 12 May 2021

View article titled, Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Journal Articles

Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

Madeline Rose Keleher, Kathryn Erickson, Harry A. Smith, Katerina J. Kechris, Ivana V. Yang, Dana Dabelea, Jacob E. Friedman, Kristen E. Boyle, Thomas Jansson

Diabetes 2021;70(3):745–751

DOI: https://doi.org/10.2337/db20-0902

Published: 07 January 2021

View article titled, Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

Journal Articles

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Melanie R. Shapiro, Clive H. Wasserfall, Sean M. McGrail, Amanda L. Posgai, Rhonda Bacher, Andrew Muir, Michael J. Haller, Desmond A. Schatz, Johnna D. Wesley, Matthias von Herrath, William A. Hagopian, Cate Speake, Mark A. Atkinson, Todd M. Brusko

Diabetes 2020;69(3):413–423

DOI: https://doi.org/10.2337/db19-0942

Published: 11 December 2020

View article titled, Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Includes: Supplementary data

Meeting Abstracts

1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

HIROFUMI NAGAO, WEIKANG CAI, THIAGO M. BATISTA, HUI PAN, JONATHAN DREYFUSS, C. RONALD KAHN

Diabetes 2020;69(Supplement_1):1737-P

DOI: https://doi.org/10.2337/db20-1737-P

Published: 01 June 2020

View article titled, 1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

Meeting Abstracts

299-OR: Loss of Insulin and IGF1 Receptors in Muscle Impairs Complex-I Dependent Mitochondrial Bioenergetics and Supercomplex Formation via Foxo Transcription Factors

GOURAV BHARDWAJ, CHRISTIE M. PENNIMAN, PABLO A. SUAREZ BELTRAN, JAYASHREE JENA, COLLIN M. FOSTER, KENNEDY PORO, TAYLOR JUNCK, ANTENTOR HINTON, RHONDA SOUVENIR, JORDAN FUQUA, PABLO E. MORALES, ROBERTO BRAVO-SAGUA, VITOR A. LIRA, EVAN D. ABEL, BRIAN T. ONEILL

Diabetes 2020;69(Supplement_1):299-OR

DOI: https://doi.org/10.2337/db20-299-OR

Published: 01 June 2020

View article titled, 299-OR: Loss of Insulin and IGF1 Receptors in Muscle Impairs Complex-I Dependent Mitochondrial Bioenergetics and Supercomplex Formation via Foxo Transcription Factors

Meeting Abstracts

720-P: Exercise Training Causes Vast Changes in the Circulating Factor Profile of Human Subjects

ROELAND MIDDELBEEK, JEFFREY J. RICHARD, LESLIE A. ROWLAND, PASQUALE NIGRO, HUI PAN, JONATHAN DREYFUSS, LAURIE J. GOODYEAR

Diabetes 2019;68(Supplement_1):720-P

DOI: https://doi.org/10.2337/db19-720-P

Published: 01 June 2019

View article titled, 720-P: Exercise Training Causes Vast Changes in the Circulating Factor Profile of Human Subjects

Meeting Abstracts

290-LB: Repeated Neonatal Oral Sucrose Treatment Affects Growth and Insulin-Like Growth Factor-1 in Mice

CYNTHIA YAMILKA RAMIREZ CONTRERAS, EI-XIA MUSSAI, ALEJANDRA M. WIEDEMAN, ARYA MEHRAN, MELODY SALEHZADEH, NICHA BOONPATTRAWONG, MANON RANGER, KIRAN K. SOMA, LIISA HOLSTI, ANGELA M. DEVLIN

Diabetes 2019;68(Supplement_1):290-LB

DOI: https://doi.org/10.2337/db19-290-LB

Published: 01 June 2019

View article titled, 290-LB: Repeated Neonatal Oral Sucrose Treatment Affects Growth and Insulin-Like Growth Factor-1 in Mice

Meeting Abstracts

1946-P: Insulin-Like Growth Factor-1 Protects against the Detrimental Effects of Advanced Glycation End Products and High Glucose in Myoblastic C2C12 Cells

IPPEI KANAZAWA, NAOKO ADACHI, KEN-ICHIRO TANAKA, AYUMU TAKENO, MASAKAZU NOTSU, SAYURI TANAKA, TOSHITSUGU SUGIMOTO

Diabetes 2019;68(Supplement_1):1946-P

DOI: https://doi.org/10.2337/db19-1946-P

Published: 01 June 2019

View article titled, 1946-P: Insulin-Like Growth Factor-1 Protects against the Detrimental Effects of Advanced Glycation End Products and High Glucose in Myoblastic C2C12 Cells

Meeting Abstracts

142-OR: Unique Role of the a4 Component for S6-Kinase Activity in Metabolic Regulation and Anti-apoptotic Effect in Brown Adipose Tissue

MASAJI SAKAGUCHI, SHOTA OKAGAWA, SAYAKA KITANO, TATSUYA KONDO, EIICHI ARAKI

Diabetes 2019;68(Supplement_1):142-OR

DOI: https://doi.org/10.2337/db19-142-OR

Published: 01 June 2019

View article titled, 142-OR: Unique Role of the a4 Component for S6-Kinase Activity in Metabolic Regulation and Anti-apoptotic Effect in Brown Adipose Tissue

Meeting Abstracts

Longitudinal Predictors of Insulin Sensitivity and Secretion during Puberty

MEGAN M. KELSEY, LAURA PYLE, ALLISON M. HILKIN, AIMEE JOHNSON, KRISTEN J. NADEAU, PHIL ZEITLER

Diabetes 2018;67(Supplement_1):1348-P

DOI: https://doi.org/10.2337/db18-1348-P

Published: 01 July 2018

View article titled, Longitudinal Predictors of Insulin Sensitivity and Secretion during Puberty

Meeting Abstracts

Diabetes Retinopathy (DR) Relates to Complication Risk in Young Persons with T1D

MICHELLE KATZ, GEORGE L. KING, JENNIFER SUN, LORI M. LAFFEL

Diabetes 2018;67(Supplement_1):1367-P

DOI: https://doi.org/10.2337/db18-1367-P

Published: 01 July 2018

View article titled, Diabetes Retinopathy (DR) Relates to Complication Risk in Young Persons with T1D

Meeting Abstracts

Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance

JUN HOSOE, HIROKO KADOWAKI, FUYUKI MIYA, MINAKA TAKAKURA, TATSUHIKO TSUNODA, NOBUHIRO SHOJIMA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI

Diabetes 2018;67(Supplement_1):1349-P

DOI: https://doi.org/10.2337/db18-1349-P

Published: 01 July 2018

View article titled, Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance

Meeting Abstracts

Association between IGF1/IGFBP3 with Lipid Metabolism and Chronic Low-Grade Inflammation and Alteration after Laparoscopic Sleeve Gastrectomy in Chinese Obese Subjects

LIANG LI, XINGCHUN WANG, JINGYANG GAO, SHEN QU

Diabetes 2018;67(Supplement_1):2457-PUB

DOI: https://doi.org/10.2337/db18-2457-PUB

Published: 01 July 2018

View article titled, Association between IGF1/IGFBP3 with Lipid Metabolism and Chronic Low-Grade Inflammation and Alteration after Laparoscopic Sleeve Gastrectomy in Chinese Obese Subjects

Journal Articles

The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?

Ravi Retnakaran

Diabetes 2016;65(11):3246–3248

DOI: https://doi.org/10.2337/dbi16-0048

Published: 12 October 2016

View article titled, The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?

Journal Articles

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Diabetes 2017;66(1):64–74

DOI: https://doi.org/10.2337/db16-0861

Published: 10 October 2016

View article titled, Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Includes: Supplementary data

Journal Articles

Growth Hormone Control of Hepatic Lipid Metabolism

Zhongbo Liu, Jose Cordoba-Chacon, Rhonda D. Kineman, Bruce N. Cronstein, Radhika Muzumdar, Zhenwei Gong, Haim Werner, Shoshana Yakar

Diabetes 2016;65(12):3598–3609

DOI: https://doi.org/10.2337/db16-0649

Published: 27 September 2016

View article titled, Growth Hormone Control of Hepatic Lipid Metabolism

Includes: Supplementary data

Journal Articles

Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort

Yeyi Zhu, Pauline Mendola, Paul S. Albert, Wei Bao, Stefanie N. Hinkle, Michael Y. Tsai, Cuilin Zhang

Diabetes 2016;65(11):3495–3504

DOI: https://doi.org/10.2337/db16-0514

Published: 28 July 2016

View article titled, Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort

Includes: Supplementary data

NARROW

Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle

97-LB: The DERMIS Study—Preliminary Evaluation of Skin Changes at Continuous Subcutaneous Insulin Infusion (CSII) Sites in Type 1 Diabetes (T1D)

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

299-OR: Loss of Insulin and IGF1 Receptors in Muscle Impairs Complex-I Dependent Mitochondrial Bioenergetics and Supercomplex Formation via Foxo Transcription Factors

720-P: Exercise Training Causes Vast Changes in the Circulating Factor Profile of Human Subjects

290-LB: Repeated Neonatal Oral Sucrose Treatment Affects Growth and Insulin-Like Growth Factor-1 in Mice

1946-P: Insulin-Like Growth Factor-1 Protects against the Detrimental Effects of Advanced Glycation End Products and High Glucose in Myoblastic C2C12 Cells

142-OR: Unique Role of the a4 Component for S6-Kinase Activity in Metabolic Regulation and Anti-apoptotic Effect in Brown Adipose Tissue

Longitudinal Predictors of Insulin Sensitivity and Secretion during Puberty

Diabetes Retinopathy (DR) Relates to Complication Risk in Young Persons with T1D

Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance

Association between IGF1/IGFBP3 with Lipid Metabolism and Chronic Low-Grade Inflammation and Alteration after Laparoscopic Sleeve Gastrectomy in Chinese Obese Subjects

The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Growth Hormone Control of Hepatic Lipid Metabolism

Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort

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