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Meeting Abstracts

1656-P: Glucagon-Like peptide-1 (GLP-1) Secretion from Intestinal L-Cells Is Mediated by hERG Potassium Channels

JIN-KUI YANG, CHANG LIU, HAO WANG, YINGCHAO YUAN

Diabetes 2023;72(Supplement_1):1656-P

https://doi.org/10.2337/db23-1656-P

Published: 20 June 2023

View article titled, 1656-P: Glucagon-Like peptide-1 (GLP-1) Secretion from Intestinal L-Cells Is Mediated by hERG Potassium Channels

Meeting Abstracts

228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

ERYUN ZHANG, WENDONG HUANG

Diabetes 2023;72(Supplement_1):228-LB

https://doi.org/10.2337/db23-228-LB

Published: 20 June 2023

View article titled, 228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

Meeting Abstracts

206-OR: A Human Gut Commensal, Parabacteroides distasonis, Stimulates an Inflammatory Response Specific to the Pancreas but Not to the Intestines, and Induces Type 1 Diabetes

KHYATI GIRDHAR, AMOL RAISINGANI, EMRAH ALTINDIS

Diabetes 2023;72(Supplement_1):206-OR

https://doi.org/10.2337/db23-206-OR

Published: 20 June 2023

View article titled, 206-OR: A Human Gut Commensal, Parabacteroides distasonis, Stimulates an Inflammatory Response Specific to the Pancreas but Not to the Intestines, and Induces Type 1 Diabetes

Meeting Abstracts

289-LB: Intestinal Stem Cells as a Source of Insulin-Positive Beta-Like Cells for Treating Diabetes

YU XIAO, YAO XIAO, YINAN JIANG

Diabetes 2023;72(Supplement_1):289-LB

https://doi.org/10.2337/db23-289-LB

Published: 20 June 2023

View article titled, 289-LB: Intestinal Stem Cells as a Source of Insulin-Positive Beta-Like Cells for Treating Diabetes

Meeting Abstracts

882-P: Effects of YG1699 and Sotagliflozin on Intestinal Glucose Absorption and GLP-1 in Mice

JACKY LI, ROGER W. XU, JIAOJUAN HE, PABLO LAPUERTA

Diabetes 2023;72(Supplement_1):882-P

https://doi.org/10.2337/db23-882-P

Published: 20 June 2023

View article titled, 882-P: Effects of YG1699 and Sotagliflozin on Intestinal Glucose Absorption and GLP-1 in Mice

Meeting Abstracts

1679-P: L-arginine Ameliorates Polycystic Ovary Syndrome and Attenuates Intestinal Oxidative Stress by Regulating Gut Microbiota

DILIQINGNA DILIMULATI, MEILI CAI, YUQIN ZHANG, SHEN QU, MANNA ZHANG

Diabetes 2023;72(Supplement_1):1679-P

https://doi.org/10.2337/db23-1679-P

Published: 20 June 2023

View article titled, 1679-P: L-arginine Ameliorates Polycystic Ovary Syndrome and Attenuates Intestinal Oxidative Stress by Regulating Gut Microbiota

Meeting Abstracts

1708-P: Comparing 9- vs. 12-Month Implantation in the Worldwide EndoBarrier (EB) Registry

ROBERT E. RYDER, MAHENDER YADAGIRI, LYNNE MUNRO, HARRY FRYDENBERG, SIGAL FISHMAN, JAMES P. BYRNE, JULIAN P. TEARE, CHARLOTTE DE JONGE, JAN WILLEM GREVE, JESSICA J. MCMASTER, JACOB CHISHOLM, LILIAN KOW, JOHN C. MASON, RICARDO V. COHEN, PIYA SEN GUPTA

Diabetes 2023;72(Supplement_1):1708-P

https://doi.org/10.2337/db23-1708-P

Published: 20 June 2023

View article titled, 1708-P: Comparing 9- vs. 12-Month Implantation in the Worldwide EndoBarrier (EB) Registry

Meeting Abstracts

866-P: Quantitative Analysis of Metformin-Induced Glucose Excretion in the Intestine

YUSEI HOSOKAWA, KAZUHIKO SAKAGUCHI, JUN ITO, KENJI SUGAWARA, YASUKO MORITA, WATARU OGAWA

Diabetes 2023;72(Supplement_1):866-P

https://doi.org/10.2337/db23-866-P

Published: 20 June 2023

View article titled, 866-P: Quantitative Analysis of Metformin-Induced Glucose Excretion in the Intestine

Meeting Abstracts

1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of Akkermansia muciniphila

YOSHIYUKI WATANABE, SHIHO FUJISAKA, SHIRO WATANABE, AYUMI NISHIMURA, TOMONOBU KADO, MUHAMMAD RAHIL ASLAM, MUHAMMAD BILAL, YOSHITOMO MORINAGA, KAZUYUKI TOBE

Diabetes 2023;72(Supplement_1):1672-P

https://doi.org/10.2337/db23-1672-P

Published: 20 June 2023

View article titled, 1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of <em>Akkermansia muciniphila</em>

Meeting Abstracts

1415-P: Risk–Benefit Data from the Worldwide EndoBarrier (EB) Registry

Diabetes 2022;71(Supplement_1):1415-P

https://doi.org/10.2337/db22-1415-P

Published: 01 June 2022

View article titled, 1415-P: Risk–Benefit Data from the Worldwide EndoBarrier (EB) Registry

Meeting Abstracts

466-P: Changes in Oral and Intestinal Bacterial Flora Associated with Pain Thresholds

KAZUHIRO KUDOH, YUKI TAKEUCHI, SHO OSONOI, TAKANORI SASAKI, SAORI OGASAWARA, SOROKU YAGIHASHI, HIROKI MIZUKAMI

Diabetes 2022;71(Supplement_1):466-P

https://doi.org/10.2337/db22-466-P

Published: 01 June 2022

View article titled, 466-P: Changes in Oral and Intestinal Bacterial Flora Associated with Pain Thresholds

Meeting Abstracts

1362-P: Endogenous Glucose-Dependent Insulinotropic Polypeptide Facilitates Postprandial Intestinal Lipid Uptake in Healthy Men, but Not in Patients with Type 2 Diabetes

LÆRKE S. GASBJERG, MADS M. HELSTED, SIGNE STENSEN, LIVA S.L. KROGH, ALEXANDER H. SPARRE-ULRICH, BOLETTE HARTMANN, TINA VILSBØLL, MIKKEL B. CHRISTENSEN, JENS J. HOLST, CHRISTINA CHRISTOFFERSEN, FILIP K. KNOP, METTE M. ROSENKILDE

Diabetes 2022;71(Supplement_1):1362-P

https://doi.org/10.2337/db22-1362-P

Published: 01 June 2022

View article titled, 1362-P: Endogenous Glucose-Dependent Insulinotropic Polypeptide Facilitates Postprandial Intestinal Lipid Uptake in Healthy Men, but Not in Patients with Type 2 Diabetes

Meeting Abstracts

1357-P: Diabetic Hyperglycemia Impairs Intestinal Barrier Function in the Setting of Diet-Induced Obesity

KENDRA L. FRANCIS, KIMBERLY M. ALONGE, SHANNON J.W. HU, BAO ANH N. PHAN, TAMMY P. DOAN, CODY A. KRUTZSCH, ZENOURA MAAT, JARRAD M. SCARLETT, MICHAEL W. SCHWARTZ

Diabetes 2022;71(Supplement_1):1357-P

https://doi.org/10.2337/db22-1357-P

Published: 01 June 2022

View article titled, 1357-P: Diabetic Hyperglycemia Impairs Intestinal Barrier Function in the Setting of Diet-Induced Obesity

Meeting Abstracts

847-P: Assessment of Intestinal Microbiota in African-Americans Diabetics Thriving on or Not Tolerating This Drug

MAYA FAYFMAN, SHANTHI SRINIVASAN, GUILLERMO E. UMPIERREZ, GERARDO BLANCO, ANDREW GEWIRTZ, BENOIT CHASSAING

Diabetes 2022;71(Supplement_1):847-P

https://doi.org/10.2337/db22-847-P

Published: 01 June 2022

View article titled, 847-P: Assessment of Intestinal Microbiota in African-Americans Diabetics Thriving on or Not Tolerating This Drug

Meeting Abstracts

1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

ERYUN ZHANG

Diabetes 2022;71(Supplement_1):1297-P

https://doi.org/10.2337/db22-1297-P

Published: 01 June 2022

View article titled, 1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

Journal Articles

Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance

Sinju Sundaresan, Joseph Antoun, Babak Banan, Jamie Adcock, Connor Johnson, Brendan Claire, Kala Dixon, Joyce Flynn, Cyndya A. Shibao, Naji Abumrad

Diabetes 2022;71(7):1424–1438

https://doi.org/10.2337/db21-0708

Published: 27 April 2022

View article titled, Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance

Journal Articles

GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling

Elisabeth M. Grande, Fitore Raka, Simon Hoffman, Khosrow Adeli

Diabetes 2022;71(7):1388–1399

https://doi.org/10.2337/db21-1053

Published: 27 April 2022

View article titled, GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling

Journal Articles

Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Diabetes 2022;71(5):1023–1033

https://doi.org/10.2337/db21-0574

Published: 31 January 2022

View article titled, Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Journal Articles

Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases

Diabetes 2021;70(9):2067–2080

https://doi.org/10.2337/db20-1177

Published: 02 June 2021

View article titled, Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases

Meeting Abstracts

260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis

SARAH E. MARTCHENKO, ALEXANDRE MARTCHENKO, ANDREW BIANCOLIN, PATRICIA L. BRUBAKER

Diabetes 2021;70(Supplement_1):260-OR

https://doi.org/10.2337/db21-260-OR

Published: 01 June 2021

View article titled, 260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis

NARROW

1656-P: Glucagon-Like peptide-1 (GLP-1) Secretion from Intestinal L-Cells Is Mediated by hERG Potassium Channels

228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

206-OR: A Human Gut Commensal, Parabacteroides distasonis, Stimulates an Inflammatory Response Specific to the Pancreas but Not to the Intestines, and Induces Type 1 Diabetes

289-LB: Intestinal Stem Cells as a Source of Insulin-Positive Beta-Like Cells for Treating Diabetes

882-P: Effects of YG1699 and Sotagliflozin on Intestinal Glucose Absorption and GLP-1 in Mice

1679-P: L-arginine Ameliorates Polycystic Ovary Syndrome and Attenuates Intestinal Oxidative Stress by Regulating Gut Microbiota

1708-P: Comparing 9- vs. 12-Month Implantation in the Worldwide EndoBarrier (EB) Registry

866-P: Quantitative Analysis of Metformin-Induced Glucose Excretion in the Intestine

1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of Akkermansia muciniphila

1415-P: Risk–Benefit Data from the Worldwide EndoBarrier (EB) Registry

466-P: Changes in Oral and Intestinal Bacterial Flora Associated with Pain Thresholds

1362-P: Endogenous Glucose-Dependent Insulinotropic Polypeptide Facilitates Postprandial Intestinal Lipid Uptake in Healthy Men, but Not in Patients with Type 2 Diabetes

1357-P: Diabetic Hyperglycemia Impairs Intestinal Barrier Function in the Setting of Diet-Induced Obesity

847-P: Assessment of Intestinal Microbiota in African-Americans Diabetics Thriving on or Not Tolerating This Drug

1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance

GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling

Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases

260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis

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