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Meeting Abstracts

260-LB: The Effect of LXR Activation on Liver Metabolism and Diet-Induced Steatohepatitis in Mice

TOMASZ BEDNARSKI, MOHSIN RAHIM, NOAH WHITTENBARGER, ADAM J. OLICHWIER, JAMEY YOUNG
Journal: Diabetes
Diabetes 2023;72(Supplement_1):260-LB
https://doi.org/10.2337/db23-260-LB
Published: 20 June 2023
View article titled, 260-LB: The Effect of LXR Activation on Liver Metabolism and Diet-Induced Steatohepatitis in Mice
Meeting Abstracts

248-OR: Diabetes Remission after Gastric Bypass Is Characterized by Upregulation of LXR and Antioxidant-Related Pathways in Jejunum

MARGARET A. STEFATER-RICHARDS, WILLIAM F. GOURASH, ANITA COURCOULAS
Journal: Diabetes
Diabetes 2023;72(Supplement_1):248-OR
https://doi.org/10.2337/db23-248-OR
Published: 20 June 2023
View article titled, 248-OR: Diabetes Remission after Gastric Bypass Is Characterized by Upregulation of LXR and Antioxidant-Related Pathways in Jejunum
Journal Articles

Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice

Stéphanie A. Eid, Mohamed El Massry, Mehdi Hichor, Mary Haddad, Julien Grenier, Batoul Dia, Rasha Barakat, Suzan Boutary, Johan Chanal, Selim Aractingi, Philippe Wiesel, Cédric Szyndralewiez, Sami T. Azar, Christian Boitard, Ghazi Zaatari, Assaad A. Eid, Charbel Massaad
Journal: Diabetes
Diabetes 2020;69(3):448–464
https://doi.org/10.2337/db19-0517
Published: 27 December 2020
View article titled, Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice
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Meeting Abstracts

1888-P: Activation of Myocardial Mitochondrial Akt1 Remotely Modulated Body Composition and Adiposity through LXR/RXR Signaling

YU-HAN CHEN, ALBERT TA, EMILY TOM, YUMAY CHEN, PING H. WANG
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1888-P
https://doi.org/10.2337/db20-1888-P
Published: 01 June 2020
View article titled, 1888-P: Activation of Myocardial Mitochondrial Akt1 Remotely Modulated Body Composition and Adiposity through LXR/RXR Signaling
Journal Articles

Epigenetic Regulation of Hepatic Lipogenesis: Role in Hepatosteatosis and Diabetes

Jose Viscarra, Hei Sook Sul
Journal: Diabetes
Diabetes 2020;69(4):525–531
https://doi.org/10.2337/dbi18-0032
Published: 16 March 2020
View article titled, Epigenetic Regulation of Hepatic Lipogenesis: Role in Hepatosteatosis and Diabetes
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Journal Articles

Programmed Cell Death-4 Deficiency Prevents Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance

Qun Wang, Zhaojing Dong, Xianglan Liu, Xingguo Song, Qiang Song, Qianwen Shang, Yang Jiang, Chun Guo, Lining Zhang
Journal: Diabetes
Diabetes 2013;62(12):4132–4143
https://doi.org/10.2337/db13-0097
Published: 16 November 2013
View article titled, Programmed Cell Death-4 Deficiency Prevents Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance
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Includes: Supplementary data
Journal Articles

Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes

Sugata Hazra, Adil Rasheed, Ashay Bhatwadekar, Xiaoxin Wang, Lynn C. Shaw, Monika Patel, Sergio Caballero, Lilia Magomedova, Nathaniel Solis, Yuanqing Yan, Weidong Wang, Jeffrey S. Thinschmidt, Amrisha Verma, Qiuhong Li, Moshe Levi, Carolyn L. Cummins, Maria B. Grant
Journal: Diabetes
Diabetes 2012;61(12):3270–3279
https://doi.org/10.2337/db11-1596
Published: 15 November 2012
View article titled, Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes
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Journal Articles

Class II Histone Deacetylases Downregulate GLUT4 Transcription in Response to Increased cAMP Signaling in Cultured Adipocytes and Fasting Mice

Juston C. Weems, Beth A. Griesel, Ann Louise Olson
Journal: Diabetes
Diabetes 2012;61(6):1404–1414
https://doi.org/10.2337/db11-0737
Published: 14 May 2012
View article titled, Class II Histone Deacetylases Downregulate <em>GLUT4</em> Transcription in Response to Increased cAMP Signaling in Cultured Adipocytes and Fasting Mice
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Journal Articles

Liver X Receptor α Is Involved in the Transcriptional Regulation of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase Gene

Li-Feng Zhao, Yasumasa Iwasaki, Mitsuru Nishiyama, Takafumi Taguchi, Makoto Tsugita, Mizuho Okazaki, Shuichi Nakayama, Machiko Kambayashi, Shimpei Fujimoto, Koshi Hashimoto, Koji Murao, Yoshio Terada
Journal: Diabetes
Diabetes 2012;61(5):1062–1071
https://doi.org/10.2337/db11-1255
Published: 13 April 2012
View article titled, Liver X Receptor α Is Involved in the Transcriptional Regulation of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase Gene
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Journal Articles

Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling

Beth A. Griesel, Juston Weems, Robert A. Russell, E. Dale Abel, Kenneth Humphries, Ann Louise Olson
Journal: Diabetes
Diabetes 2010;59(4):800–807
https://doi.org/10.2337/db09-1542
Published: 26 January 2010
View article titled, Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling
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Journal Articles

Chronic Activation of Liver X Receptor Induces β-Cell Apoptosis Through Hyperactivation of Lipogenesis: Liver X Receptor–Mediated Lipotoxicity in Pancreatic β-Cells

Sung Sik Choe, A Hyun Choi, Joo-Won Lee, Kang Ho Kim, Jun-Jae Chung, Jiyoung Park, Kyeong-Min Lee, Keun-Gyu Park, In-Kyu Lee, Jae Bum Kim
Journal: Diabetes
Diabetes 2007;56(6):1534–1543
https://doi.org/10.2337/db06-1059
Published: 01 June 2007
View article titled, Chronic Activation of Liver X Receptor Induces β-Cell Apoptosis Through Hyperactivation of Lipogenesis: <subtitle>Liver X Receptor–Mediated Lipotoxicity in Pancreatic β-Cells</subtitle>
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Includes: Supplementary data
Journal Articles

Regulation of Renal Fatty Acid and Cholesterol Metabolism, Inflammation, and Fibrosis in Akita and OVE26 Mice With Type 1 Diabetes

Gregory Proctor, Tao Jiang, Mieko Iwahashi, Zhuowei Wang, Jinping Li, Moshe Levi
Journal: Diabetes
Diabetes 2006;55(9):2502–2509
https://doi.org/10.2337/db05-0603
Published: 01 September 2006
View article titled, Regulation of Renal Fatty Acid and Cholesterol Metabolism, Inflammation, and Fibrosis in Akita and OVE26 Mice With Type 1 Diabetes
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Journal Articles

Skeletal Muscle Lipid Accumulation in Type 2 Diabetes May Involve the Liver X Receptor Pathway

Eili T. Kase, Andreas J. Wensaas, Vigdis Aas, Kurt Højlund, Klaus Levin, G. Hege Thoresen, Henning Beck-Nielsen, Arild C. Rustan, Michael Gaster
Journal: Diabetes
Diabetes 2005;54(4):1108–1115
https://doi.org/10.2337/diabetes.54.4.1108
Published: 01 April 2005
View article titled, Skeletal Muscle Lipid Accumulation in Type 2 Diabetes May Involve the Liver X Receptor Pathway
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Journal Articles

Liver X Receptor Activation Stimulates Insulin Secretion via Modulation of Glucose and Lipid Metabolism in Pancreatic Beta-Cells

Alexander M. Efanov, Sabine Sewing, Krister Bokvist, Jesper Gromada
Journal: Diabetes
Diabetes 2004;53(suppl_3):S75–S78
https://doi.org/10.2337/diabetes.53.suppl_3.S75
Published: 01 December 2004
View article titled, Liver X Receptor Activation Stimulates Insulin Secretion via Modulation of Glucose and Lipid Metabolism in Pancreatic Beta-Cells
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Journal Articles

Putative Metabolic Effects of the Liver X Receptor (LXR)

Knut R. Steffensen, Jan-Åke Gustafsson
Journal: Diabetes
Diabetes 2004;53(suppl_1):S36–S42
https://doi.org/10.2337/diabetes.53.2007.S36
Published: 01 February 2004
View article titled, Putative Metabolic Effects of the Liver X Receptor (LXR)
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Journal Articles

Mechanisms of the Triglyceride- and Cholesterol-Lowering Effect of Fenofibrate in Hyperlipidemic Type 2 Diabetic Patients

Fabien Forcheron, Ana Cachefo, Sylvie Thevenon, Claudie Pinteur, Michel Beylot
Journal: Diabetes
Diabetes 2002;51(12):3486–3491
https://doi.org/10.2337/diabetes.51.12.3486
Published: 01 December 2002
View article titled, Mechanisms of the Triglyceride- and Cholesterol-Lowering Effect of Fenofibrate in Hyperlipidemic Type 2 Diabetic Patients
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Journal Articles

Liver X Receptors Downregulate 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity

Thomas M. Stulnig, Udo Oppermann, Knut R. Steffensen, Gertrud U. Schuster, Jan-Åke Gustafsson
Journal: Diabetes
Diabetes 2002;51(8):2426–2433
https://doi.org/10.2337/diabetes.51.8.2426
Published: 01 August 2002
View article titled, Liver X Receptors Downregulate 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity
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