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Journal Articles

Leukocyte Counts and T-Cell Frequencies Differ Between Novel Subgroups of Diabetes and Are Associated With Metabolic Parameters and Biomarkers of Inflammation

Jacqueline M. Ratter-Rieck, Haifa Maalmi, Sandra Trenkamp, Oana-Patricia Zaharia, Wolfgang Rathmann, Nanette C. Schloot, Klaus Straßburger, Julia Szendroedi, Christian Herder, Michael Roden
Journal: Diabetes
Diabetes 2021;70(11):2652–2662
DOI: https://doi.org/10.2337/db21-0364
Published: 30 August 2021
View article titled, Leukocyte Counts and T-Cell Frequencies Differ Between Novel Subgroups of Diabetes and Are Associated With Metabolic Parameters and Biomarkers of Inflammation
Click here to open pdf in another window PDF for Leukocyte Counts and T-Cell Frequencies Differ Between Novel Subgroups of Diabetes and Are Associated With Metabolic Parameters and Biomarkers of Inflammation
Journal Articles

A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity

Nitzan Maixner, Tal Pecht, Yulia Haim, Vered Chalifa-Caspi, Nir Goldstein, Tania Tarnovscki, Idit F. Liberty, Boris Kirshtein, Rachel Golan, Omer Berner, Alon Monsonego, Nava Bashan, Matthias Blüher, Assaf Rudich
Journal: Diabetes
Diabetes 2020;69(11):2310–2323
DOI: https://doi.org/10.2337/db19-1231
Published: 30 July 2020
View article titled, A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity
Click here to open pdf in another window PDF for A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity
Meeting Abstracts

567-P: The Neutrophil-to-Lymphocyte Ratio as a Biomarker of Diabetic Retinopathy: A Cross-Sectional Study

MEI LI, XIXIANG TANG, YING TAN, YUANPENG NIE, HAICHENG LI, YANMING CHEN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):567-P
DOI: https://doi.org/10.2337/db20-567-P
Published: 01 June 2020
View article titled, 567-P: The Neutrophil-to-Lymphocyte Ratio as a Biomarker of Diabetic Retinopathy: A Cross-Sectional Study
Meeting Abstracts

Subclinical Inflammation and Lymphocytes in Subcutaneous and Visceral Adipose Tissue—The Influence of Pregnancy and Gestational Diabetes Mellitus

ANNA CINKAJZLOVA, KATEřINA ANDERLOVÁ, PATRIK SIMJAK, ZDENA LACINOVÁ, JANA KLOUCKOVA, HELENA KRATOCHVILOVA, HANA KREJCI, MILOS MRAZ, MARTIN HALUZIK, MICHAL KRSEK
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1413-P
DOI: https://doi.org/10.2337/db18-1413-P
Published: 01 July 2018
View article titled, Subclinical Inflammation and Lymphocytes in Subcutaneous and Visceral Adipose Tissue—The Influence of Pregnancy and Gestational Diabetes Mellitus
Meeting Abstracts

Characterization of Islet-Infiltrating Lymphocytes in Type 1 Diabetes

JAMIE L. FELTON, RACHEL H. BONAMI, CHRYS HULBERT, JAMES W. THOMAS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):226-LB
DOI: https://doi.org/10.2337/db18-226-LB
Published: 01 July 2018
View article titled, Characterization of Islet-Infiltrating Lymphocytes in Type 1 Diabetes
Meeting Abstracts

The Role of Epicardial Adipose Tissue Lymphocytes in Low-Grade Inflammation and Coronary Artery Disease

MILOS MRAZ, ANNA CINKAJZLOVA, ZDENA LACINOVÁ, JANA KLOUCKOVA, HELENA KRATOCHVILOVA, MICHAL LIPS, PETR KOPECKY, MICHAL PORIZKA, JAROSLAV LINDNER, MARTIN HALUZIK
Journal: Diabetes
Diabetes 2018;67(Supplement_1):469-P
DOI: https://doi.org/10.2337/db18-469-P
Published: 01 July 2018
View article titled, The Role of Epicardial Adipose Tissue Lymphocytes in Low-Grade Inflammation and Coronary Artery Disease
Journal Articles

Anti-CD3/Anti-CXCL10 Antibody Combination Therapy Induces a Persistent Remission of Type 1 Diabetes in Two Mouse Models

Stanley Lasch, Peter Müller, Monika Bayer, Josef M. Pfeilschifter, Andrew D. Luster, Edith Hintermann, Urs Christen
Journal: Diabetes
Diabetes 2015;64(12):4198–4211
DOI: https://doi.org/10.2337/db15-0479
Published: 20 August 2015
View article titled, Anti-CD3/Anti-CXCL10 Antibody Combination Therapy Induces a Persistent Remission of Type 1 Diabetes in Two Mouse Models
Click here to open pdf in another window PDF for Anti-CD3/Anti-CXCL10 Antibody Combination Therapy Induces a Persistent Remission of Type 1 Diabetes in Two Mouse Models
Includes: Supplementary data
Journal Articles

An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes

Wilfredo Rosario, David D’Alessio
Journal: Diabetes
Diabetes 2015;64(7):2329–2331
DOI: https://doi.org/10.2337/db15-0436
Published: 17 June 2015
View article titled, An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes
Click here to open pdf in another window PDF for An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes
Journal Articles

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

Ercument Dirice, Sevim Kahraman, Wenyu Jiang, Abdelfattah El Ouaamari, Dario F. De Jesus, Adrian K.K. Teo, Jiang Hu, Dan Kawamori, Jason L. Gaglia, Diane Mathis, Rohit N. Kulkarni
Journal: Diabetes
Diabetes 2014;63(1):188–202
DOI: https://doi.org/10.2337/db13-0204
Published: 13 December 2013
View article titled, Soluble Factors Secreted by T Cells Promote β-Cell Proliferation
Click here to open pdf in another window PDF for Soluble Factors Secreted by T Cells Promote β-Cell Proliferation
Includes: Supplementary data
Journal Articles

ZnT8 Is a Major CD8+ T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes

Émmanuelle Énée, Roland Kratzer, Jean-Baptiste Arnoux, Emilie Barilleau, Yamina Hamel, Christophe Marchi, Jacques Beltrand, Bénédicte Michaud, Lucienne Chatenoud, Jean-Jacques Robert, Peter van Endert
Journal: Diabetes
Diabetes 2012;61(7):1779–1784
DOI: https://doi.org/10.2337/db12-0071
Published: 15 June 2012
View article titled, ZnT8 Is a Major CD8<sup>+</sup> T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes
Click here to open pdf in another window PDF for ZnT8 Is a Major CD8<sup>+</sup> T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes
Includes: Supplementary data
Journal Articles

Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5

Emma E. Hamilton-Williams, Jocelyn Cheung, Daniel B. Rainbow, Kara M. Hunter, Linda S. Wicker, Linda A. Sherman
Journal: Diabetes
Diabetes 2012;61(1):166–174
DOI: https://doi.org/10.2337/db11-0790
Published: 12 December 2011
View article titled, Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5
Click here to open pdf in another window PDF for Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5
Includes: Supplementary data
Journal Articles

Glycosylation Failure Extends to Glycoproteins in Gestational Diabetes Mellitus: Evidence From Reduced α2-6 Sialylation and Impaired Immunomodulatory Activities of Pregnancy-Related Glycodelin-A

Cheuk-Lun Lee, Philip C.N. Chiu, Poh-Choo Pang, Ivan K. Chu, Kai-Fai Lee, Riitta Koistinen, Hannu Koistinen, Markku Seppälä, Howard R. Morris, Bérangère Tissot, Maria Panico, Anne Dell, William S.B. Yeung
Journal: Diabetes
Diabetes 2011;60(3):909–917
DOI: https://doi.org/10.2337/db10-1186
Published: 21 February 2011
View article titled, Glycosylation Failure Extends to Glycoproteins in Gestational Diabetes Mellitus: <span class="subtitle">Evidence From Reduced α2-6 Sialylation and Impaired Immunomodulatory Activities of Pregnancy-Related Glycodelin-A</span>
Click here to open pdf in another window PDF for Glycosylation Failure Extends to Glycoproteins in Gestational Diabetes Mellitus: <span class="subtitle">Evidence From Reduced α2-6 Sialylation and Impaired Immunomodulatory Activities of Pregnancy-Related Glycodelin-A</span>
Includes: Supplementary data
Journal Articles

Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation : An Epigenetic Study in Diabetes

Feng Miao, David D. Smith, Lingxiao Zhang, Andrew Min, Wei Feng, Rama Natarajan
Journal: Diabetes
Diabetes 2008;57(12):3189–3198
DOI: https://doi.org/10.2337/db08-0645
Published: 01 December 2008
View article titled, Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation : <span class="subtitle">An Epigenetic Study in Diabetes</span>
Click here to open pdf in another window PDF for Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation : <span class="subtitle">An Epigenetic Study in Diabetes</span>
Includes: Supplementary data
Journal Articles

Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : A Novel Risk Factor for Disease-Related Early Death

Bernhard O. Boehm, Peter Möller, Josef Högel, Bernhard R. Winkelmann, Wilfried Renner, Silke Rosinger, Ursula Seelhorst, Britta Wellnitz, Winfried März, Julia Melzner, Silke Brüderlein
Journal: Diabetes
Diabetes 2008;57(11):2950–2957
DOI: https://doi.org/10.2337/db08-0274
Published: 01 November 2008
View article titled, Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : <span class="subtitle">A Novel Risk Factor for Disease-Related Early Death</span>
Click here to open pdf in another window PDF for Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : <span class="subtitle">A Novel Risk Factor for Disease-Related Early Death</span>
Journal Articles

Sphingosine-1-Phosphate Reduces CD4+ T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69

Suseela Srinivasan, David T. Bolick, Dmitriy Lukashev, Courtney Lappas, Michail Sitkovsky, Kevin R. Lynch, Catherine C. Hedrick
Journal: Diabetes
Diabetes 2008;57(2):484–493
DOI: https://doi.org/10.2337/db07-0855
Published: 01 February 2008
View article titled, Sphingosine-1-Phosphate Reduces CD4<sup>+</sup> T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69
Click here to open pdf in another window PDF for Sphingosine-1-Phosphate Reduces CD4<sup>+</sup> T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69
Journal Articles

Murine Antithymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time-Dependent Induction of Immunoregulation

Greg Simon, Matthew Parker, Vijayakumar Ramiya, Clive Wasserfall, Yanfei Huang, Damien Bresson, R. Fletcher Schwartz, Martha Campbell-Thompson, Lauren Tenace, Todd Brusko, Song Xue, Abraham Scaria, Michael Lukason, Scott Eisenbeis, John Williams, Michael Clare-Salzler, Desmond Schatz, Bruce Kaplan, Matthias Von Herrath, Karl Womer, Mark A. Atkinson
Journal: Diabetes
Diabetes 2008;57(2):405–414
DOI: https://doi.org/10.2337/db06-1384
Published: 01 February 2008
View article titled, Murine Antithymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time-Dependent Induction of Immunoregulation
Click here to open pdf in another window PDF for Murine Antithymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time-Dependent Induction of Immunoregulation
Includes: Supplementary data
Journal Articles

Aberrant Endometrial Features of Pregnancy in Diabetic NOD Mice

Suzanne D. Burke, Hongmei Dong, Aleah D. Hazan, B. Anne Croy
Journal: Diabetes
Diabetes 2007;56(12):2919–2926
DOI: https://doi.org/10.2337/db07-0773
Published: 01 December 2007
View article titled, Aberrant Endometrial Features of Pregnancy in Diabetic NOD Mice
Click here to open pdf in another window PDF for Aberrant Endometrial Features of Pregnancy in Diabetic NOD Mice
Journal Articles

Expression of IGF-I in Pancreatic Islets Prevents Lymphocytic Infiltration and Protects Mice From Type 1 Diabetes

Alba Casellas, Ariana Salavert, Judith Agudo, Eduard Ayuso, Veronica Jimenez, Marta Moya, Sergio Muñoz, Sylvie Franckhauser, Fatima Bosch
Journal: Diabetes
Diabetes 2006;55(12):3246–3255
DOI: https://doi.org/10.2337/db06-0328
Published: 01 December 2006
View article titled, Expression of IGF-I in Pancreatic Islets Prevents Lymphocytic Infiltration and Protects Mice From Type 1 Diabetes
Click here to open pdf in another window PDF for Expression of IGF-I in Pancreatic Islets Prevents Lymphocytic Infiltration and Protects Mice From Type 1 Diabetes
Journal Articles

Lymphocytic Infiltration and Immune Activation in Metallothionein Promoter–Exendin-4 (MT-Exendin) Transgenic Mice

Laurie L. Baggio, Dianne Holland, Joan Wither, Daniel J. Drucker
Journal: Diabetes
Diabetes 2006;55(6):1562–1570
DOI: https://doi.org/10.2337/db05-1502
Published: 01 June 2006
View article titled, Lymphocytic Infiltration and Immune Activation in Metallothionein Promoter–Exendin-4 (MT-Exendin) Transgenic Mice
Click here to open pdf in another window PDF for Lymphocytic Infiltration and Immune Activation in Metallothionein Promoter–Exendin-4 (MT-Exendin) Transgenic Mice
Includes: Supplementary data
Journal Articles

Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Dongmei Han, Xiumin Xu, David Baidal, Jenifer Leith, Camillo Ricordi, Rodolfo Alejandro, Norma S. Kenyon
Journal: Diabetes
Diabetes 2004;53(9):2281–2290
DOI: https://doi.org/10.2337/diabetes.53.9.2281
Published: 01 September 2004
View article titled, Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: <span class="subtitle">Elevation Precedes Clinical Evidence of Rejection</span>
Click here to open pdf in another window PDF for Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: <span class="subtitle">Elevation Precedes Clinical Evidence of Rejection</span>