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Journal Articles

Protective Renalase-deficiency in beta cells shapes immune metabolism and function in autoimmune diabetes

Kevin Bode, Tara MacDonald, Taylor Stewart, Bryhan Mendez, Erica P. Cai, Noelle Morrow, Yu-Chi Lee, Peng Yi, Stephan Kissler

Diabetes db230030

DOI: https://doi.org/10.2337/db23-0030

Published: 22 May 2023

View article titled, Protective Renalase-deficiency in beta cells shapes immune metabolism and function in autoimmune diabetes

Journal Articles

K_ATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture

Frances M. Ashcroft

Diabetes 2023;72(6):693–702

DOI: https://doi.org/10.2337/dbi22-0030

Published: 19 May 2023

View article titled, K<sub>ATP</sub> Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture

Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2022;71(12):2461–2462

DOI: https://doi.org/10.2337/db22-ti12

Published: 21 November 2022

View article titled, In This Issue of Diabetes

Journal Articles

NRF2 and Diabetes: The Good, the Bad, and the Complex

Matthew Dodson, Aryatara Shakya, Annadurai Anandhan, Jinjing Chen, Joe G.N. Garcia, Donna D. Zhang

Diabetes 2022;71(12):2463–2476

DOI: https://doi.org/10.2337/db22-0623

Published: 21 November 2022

View article titled, NRF2 and Diabetes: The Good, the Bad, and the Complex

Journal Articles

Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity

Bastian Ramms, Dennis P. Pollow, Han Zhu, Chelsea Nora, Austin R. Harrington, Ibrahim Omar, Philip L.S.M. Gordts, Matthew Wortham, Maike Sander

Diabetes 2022;71(12):2513–2529

DOI: https://doi.org/10.2337/db21-1131

Published: 28 September 2022

View article titled, Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity

Journal Articles

Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy

Nikolaus Hommer, Martin Kallab, Andreas Schlatter, Kinga Howorka, René M. Werkmeister, Doreen Schmidl, Leopold Schmetterer, Gerhard Garhöfer

Diabetes 2022;71(12):2677–2684

DOI: https://doi.org/10.2337/db22-0219

Published: 15 September 2022

View article titled, Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy

Meeting Abstracts

24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

JIALIN FU, TAKANORI SHINJO, QIAN LI, KYOUNGMIN PARK, MARC GREGORY YU, HISASHI YOKOMIZO, QIAN HUANG, I-HSIEN WU, GEORGE L. KING

Diabetes 2022;71(Supplement_1):24-OR

DOI: https://doi.org/10.2337/db22-24-OR

Published: 01 June 2022

View article titled, 24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

Meeting Abstracts

1515-PUB: Opposite Effects of Low-Carbohydrate High-Fat Diet on Metabolism in Humans and Mice

XINYI XIA, LINGLI CAI, YUNJIE GU, JUN YIN

Diabetes 2022;71(Supplement_1):1515-PUB

DOI: https://doi.org/10.2337/db22-1515-PUB

Published: 01 June 2022

View article titled, 1515-PUB: Opposite Effects of Low-Carbohydrate High-Fat Diet on Metabolism in Humans and Mice

Meeting Abstracts

246-OR: Role of Skeletal Muscle Branched-Chain Amino Acid Metabolism in Exercise Training–Induced Insulin Sensitivity

MARK W. PATAKY, ARATHI PRABHA KUMAR, MATTHEW M. ROBINSON, KATHERINE KLAUS, SURENDRA DASARI, K. SREEKUMARAN NAIR

Diabetes 2022;71(Supplement_1):246-OR

DOI: https://doi.org/10.2337/db22-246-OR

Published: 01 June 2022

View article titled, 246-OR: Role of Skeletal Muscle Branched-Chain Amino Acid Metabolism in Exercise Training–Induced Insulin Sensitivity

Meeting Abstracts

1301-P: The Effect of Insulin on α-Aminoadipic Acid Metabolism in Polycystic Ovary Syndrome (PCOS) Patients with Insulin Resistance

ALICE Y. CHANG, ANEESH K. ASOKAN, DHANANJAY SAKRIKAR, ANTIGONI LALIA, MAI PETTERSON, K. SREEKUMARAN NAIR

Diabetes 2022;71(Supplement_1):1301-P

DOI: https://doi.org/10.2337/db22-1301-P

Published: 01 June 2022

View article titled, 1301-P: The Effect of Insulin on α-Aminoadipic Acid Metabolism in Polycystic Ovary Syndrome (PCOS) Patients with Insulin Resistance

Meeting Abstracts

309-OR: Lipocalin 2 Deficiency Impairs Mitochondrial Dynamics and Phospholipid Metabolism in Brown Adipocytes

HONGMING SU, HONG GUO, XIAOXUE QIU, TE-YUEH LIN, XIAOLI CHEN

Diabetes 2022;71(Supplement_1):309-OR

DOI: https://doi.org/10.2337/db22-309-OR

Published: 01 June 2022

View article titled, 309-OR: Lipocalin 2 Deficiency Impairs Mitochondrial Dynamics and Phospholipid Metabolism in Brown Adipocytes

Meeting Abstracts

1276-P: Transancestral Genomic Analysis Links Dysregulation of Valine Metabolism to the Development of Heart Failure in Type 2 Diabetes

YALING TANG, MARIE PIGEYRE, XIUQIN SUN, MARIO LUCA MORIERI, HETAL SHAH, GUILLAUME PARE, HERTZEL C. GERSTEIN, KENT TAYLOR, VASAN S. RAMACHANDRAN, JEROME I. ROTTER, STEPHEN S. RICH, JAMES B. MEIGS, ALISA MANNING, JOSYF MYCHALECKYJ, ALESSANDRO DORIA, CONSORTIUM NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED)

Diabetes 2022;71(Supplement_1):1276-P

DOI: https://doi.org/10.2337/db22-1276-P

Published: 01 June 2022

View article titled, 1276-P: Transancestral Genomic Analysis Links Dysregulation of Valine Metabolism to the Development of Heart Failure in Type 2 Diabetes

Meeting Abstracts

118-OR: Fat Distribution Patterns Predict Type 2 Diabetes Risk and Provide Insights into Prediabetic Metabolism

HAJIME YAMAZAKI, SHIN-ICHI TAUCHI, JÜRGEN MACHANN, TOBIAS HAUEISE, YOSUKE YAMAMOTO, MITSURU DOHKE, NAGISA HANAWA, YOSHIHISA KODAMA, AKIO KATANUMA, NORBERT STEFAN, ANDREAS FRITSCHE, ANDREAS L. BIRKENFELD, ROBERT WAGNER, MARTIN HENI

Diabetes 2022;71(Supplement_1):118-OR

DOI: https://doi.org/10.2337/db22-118-OR

Published: 01 June 2022

View article titled, 118-OR: Fat Distribution Patterns Predict Type 2 Diabetes Risk and Provide Insights into Prediabetic Metabolism

Meeting Abstracts

986-P: Children with Type 2 Diabetes (T2D) Have Altered Arginine Metabolism

MUSTAFA TOSUR, JEAN W. HSU, SAIMA DEEN, SERIFE UYSAL, MARCELA ASTUDILLO, MARIA J. REDONDO, FAROOK JAHOOR, ASHOK BALASUBRAMANYAM

Diabetes 2022;71(Supplement_1):986-P

DOI: https://doi.org/10.2337/db22-986-P

Published: 01 June 2022

View article titled, 986-P: Children with Type 2 Diabetes (T2D) Have Altered Arginine Metabolism

Meeting Abstracts

224-OR: Antisense Oligonucleotide–Mediated Restriction of Mitochondrial Pyruvate Metabolism Limits DNL in High-Fat Fed C57BL6/J Mice

JORDAN W. STROBER, LAUREN M. PAOLELLA, REBECCA SUH, BRANDON T. HUBBARD, SUE MURRAY, DANIEL F. VATNER

Diabetes 2022;71(Supplement_1):224-OR

DOI: https://doi.org/10.2337/db22-224-OR

Published: 01 June 2022

View article titled, 224-OR: Antisense Oligonucleotide–Mediated Restriction of Mitochondrial Pyruvate Metabolism Limits DNL in High-Fat Fed C57BL6/J Mice

Meeting Abstracts

122-LB: Effect of Dapagliflozin on Mitochondrial Metabolism and Cardiac Function in the Failing Heart

LEIGH GOEDEKE, YINA MA, JIASHENG ZHANG, NICOLE GUERRERA, XIAOHONG WU, DONGYAN ZHANG, MARIO KAHN, XIAN-MAN ZHANG, LAWRENCE H. YOUNG, GERALD I. SHULMAN

Diabetes 2022;71(Supplement_1):122-LB

DOI: https://doi.org/10.2337/db22-122-LB

Published: 01 June 2022

View article titled, 122-LB: Effect of Dapagliflozin on Mitochondrial Metabolism and Cardiac Function in the Failing Heart

Meeting Abstracts

553-P: Changes in Circulating Bile Acids and the Improvements in Glucose and Insulin Metabolism in Response to Weight-Loss Diets: The POUNDS Lost Trial

YORIKO HEIANZA, XUAN WANG, HAO MA, JENNIFER ROOD, CLARY B. CLISH, GEORGE BRAY, FRANK SACKS, LU QI

Diabetes 2022;71(Supplement_1):553-P

DOI: https://doi.org/10.2337/db22-553-P

Published: 01 June 2022

View article titled, 553-P: Changes in Circulating Bile Acids and the Improvements in Glucose and Insulin Metabolism in Response to Weight-Loss Diets: The POUNDS Lost Trial

Meeting Abstracts

299-OR: Molecular and Physiological Consequences of the Diabetes-Related PGC1A Gly482Ser Polymorphism

MARIA GALIPEAU, NATHALIE JOUVET, EMILIE COURTY, ROXANNE VANDENBEEK, NAVEEN P. KHAN, KHALIL BOUYAKDAN, CUILAN NIAN, CATERINA IORIO, DANIEL D. SCOTT, MAY FARAJ, MARLENE OEFFINGER, FRANCIS C. LYNN, ROBERT A. SCREATON, THIERRY ALQUIER, JENNIFER L. ESTALL

Diabetes 2022;71(Supplement_1):299-OR

DOI: https://doi.org/10.2337/db22-299-OR

Published: 01 June 2022

View article titled, 299-OR: Molecular and Physiological Consequences of the Diabetes-Related PGC1A Gly482Ser Polymorphism

Meeting Abstracts

1462-P: Effect of Energy Restriction on the Intracellular Metabolism of Rodent Pancreatic ß-Cells In Vitro and Obese Mice

KOKI CHIBA, HIROSHI NOMOTO, RIMI IZUMIHARA, HIRAKU KAMEDA, KYUYONG CHO, HIDEAKI MIYOSHI, TATSUYA ATSUMI

Diabetes 2022;71(Supplement_1):1462-P

DOI: https://doi.org/10.2337/db22-1462-P

Published: 01 June 2022

View article titled, 1462-P: Effect of Energy Restriction on the Intracellular Metabolism of Rodent Pancreatic ß-Cells In Vitro and Obese Mice

Meeting Abstracts

145-OR: Selenite Treatment Impacts Adipocyte Metabolism and Counteracts Detrimental Effects of Diet-Induced Insulin Resistance

ROBERT HAUFFE, MICHAELA RATH, ANDRE KLEINRIDDERS

Diabetes 2022;71(Supplement_1):145-OR

DOI: https://doi.org/10.2337/db22-145-OR

Published: 01 June 2022

View article titled, 145-OR: Selenite Treatment Impacts Adipocyte Metabolism and Counteracts Detrimental Effects of Diet-Induced Insulin Resistance

NARROW

Protective Renalase-deficiency in beta cells shapes immune metabolism and function in autoimmune diabetes

K_ATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture

In This Issue of Diabetes

NRF2 and Diabetes: The Good, the Bad, and the Complex

Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity

Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy

24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

1515-PUB: Opposite Effects of Low-Carbohydrate High-Fat Diet on Metabolism in Humans and Mice

246-OR: Role of Skeletal Muscle Branched-Chain Amino Acid Metabolism in Exercise Training–Induced Insulin Sensitivity

1301-P: The Effect of Insulin on α-Aminoadipic Acid Metabolism in Polycystic Ovary Syndrome (PCOS) Patients with Insulin Resistance

309-OR: Lipocalin 2 Deficiency Impairs Mitochondrial Dynamics and Phospholipid Metabolism in Brown Adipocytes

1276-P: Transancestral Genomic Analysis Links Dysregulation of Valine Metabolism to the Development of Heart Failure in Type 2 Diabetes

118-OR: Fat Distribution Patterns Predict Type 2 Diabetes Risk and Provide Insights into Prediabetic Metabolism

986-P: Children with Type 2 Diabetes (T2D) Have Altered Arginine Metabolism

224-OR: Antisense Oligonucleotide–Mediated Restriction of Mitochondrial Pyruvate Metabolism Limits DNL in High-Fat Fed C57BL6/J Mice

122-LB: Effect of Dapagliflozin on Mitochondrial Metabolism and Cardiac Function in the Failing Heart

553-P: Changes in Circulating Bile Acids and the Improvements in Glucose and Insulin Metabolism in Response to Weight-Loss Diets: The POUNDS Lost Trial

299-OR: Molecular and Physiological Consequences of the Diabetes-Related PGC1A Gly482Ser Polymorphism

1462-P: Effect of Energy Restriction on the Intracellular Metabolism of Rodent Pancreatic ß-Cells In Vitro and Obese Mice

145-OR: Selenite Treatment Impacts Adipocyte Metabolism and Counteracts Detrimental Effects of Diet-Induced Insulin Resistance

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