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Meeting Abstracts

1855-PUB: Generation and Identification of Pik3r3 Gene Pancreatic Beta-Cell Knockout Mice Model

XIAO-RONG ZHU

Diabetes 2023;72(Supplement_1):1855-PUB

https://doi.org/10.2337/db23-1855-PUB

Published: 23 June 2023

View article titled, 1855-PUB: Generation and Identification of Pik3r3 Gene Pancreatic Beta-Cell Knockout Mice Model

Meeting Abstracts

1608-P: Phenotype of Liver-Specific MC3R Knockout Mice

JOCELYN CHEN, TUSHAR P. PATEL, ARAD JAIN, DIANA ELIZONDO, ELIZABETH K. ALTMAN, NICOL TUGARINOV, MELANIE HOLLIS, ROBIN ROBERSON, ALEXANDRE CARON, JOEL K. ELMQUIST, JACK A. YANOVSKI

Diabetes 2023;72(Supplement_1):1608-P

https://doi.org/10.2337/db23-1608-P

Published: 20 June 2023

View article titled, 1608-P: Phenotype of Liver-Specific MC3R Knockout Mice

Meeting Abstracts

1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

FELIPE SUCUPIRA, LAYANNE ARAUJO, JOAO PAULO CAMPOREZ

Diabetes 2023;72(Supplement_1):1577-P

https://doi.org/10.2337/db23-1577-P

Published: 20 June 2023

View article titled, 1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

Meeting Abstracts

1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

OLIVER STOEHR, KYLE D. COPPS, RONGYA TAO, MORRIS F. WHITE

Diabetes 2023;72(Supplement_1):1632-P

https://doi.org/10.2337/db23-1632-P

Published: 20 June 2023

View article titled, 1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

Meeting Abstracts

1447-P: The Snd1 Coregulator Controls ß-Cell Function

SUKRATI KANOJIA, REBECCA K. DAVIDSON, JASON SPAETH, NOLAN CASEY

Diabetes 2022;71(Supplement_1):1447-P

https://doi.org/10.2337/db22-1447-P

Published: 01 June 2022

View article titled, 1447-P: The Snd1 Coregulator Controls ß-Cell Function

Meeting Abstracts

204-OR: The Chd4 Helicase Modulates ß-Cell Function In Vivo

REBECCA K. DAVIDSON, NOLAN CASEY, SUKRATI KANOJIA, JASON SPAETH

Diabetes 2022;71(Supplement_1):204-OR

https://doi.org/10.2337/db22-204-OR

Published: 01 June 2022

View article titled, 204-OR: The Chd4 Helicase Modulates ß-Cell Function In Vivo

Meeting Abstracts

207-LB: Simultaneous 2H/13C Assessment of Liver and Kidney Metabolic Fluxes Reveals Reciprocal Upregulation of Renal Gluconeogenesis in Hepatic PEPCK-C Knockout Mice

MOHSIN RAHIM, CLINTON M. HASENOUR, TOMASZ BEDNARSKI, CURTIS C. HUGHEY, DAVID WASSERMAN, JAMEY YOUNG

Diabetes 2021;70(Supplement_1):207-LB

https://doi.org/10.2337/db21-207-LB

Published: 01 June 2021

View article titled, 207-LB: Simultaneous 2H/13C Assessment of Liver and Kidney Metabolic Fluxes Reveals Reciprocal Upregulation of Renal Gluconeogenesis in Hepatic PEPCK-C Knockout Mice

Meeting Abstracts

1149-P: A Comparison between One Month vs. Two Months on a High-Fat Diet on the Impact on Glucose Metabolism in Male and Female Liver Androgen Receptor Knockout Mice

ADJOA OSEI-NTANSAH, TRINITEE R. OLIVER, CLAIRE FALZARANO, TAYLOR LOFTON, STANLEY ANDRISSE

Diabetes 2021;70(Supplement_1):1149-P

https://doi.org/10.2337/db21-1149-P

Published: 01 June 2021

View article titled, 1149-P: A Comparison between One Month vs. Two Months on a High-Fat Diet on the Impact on Glucose Metabolism in Male and Female Liver Androgen Receptor Knockout Mice

Meeting Abstracts

1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice

YUKI ISHINODA, YASUO IDO, MIDORI NOGUCHI, YUSUKE YUMITA, KAZUKI KAGAMI, AYUMU OSAKI, YASUSHI SATOH, SHOGO ENDO, AKIRA KASUGA, TAKESHI ADACHI, HIROO KUMAGAI

Diabetes 2021;70(Supplement_1):1210-P

https://doi.org/10.2337/db21-1210-P

Published: 01 June 2021

View article titled, 1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice

Journal Articles

DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation

Lin Shuai, Bo-Han Li, Hao-Wen Jiang, Lin Yang, Jia Li, Jing-Ya Li

Diabetes 2021;70(6):1317–1333

https://doi.org/10.2337/db20-1110

Published: 01 April 2021

View article titled, DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation

Meeting Abstracts

463-P: Deterioration of Atherosclerosis via Dysbiosis in ApoE Null Mice Fed with High-Salt Diet

TOMONORI KIMURA, YOSHITAKA HASHIMOTO, TAKAFUMI SENMARU, EMI USHIGOME, MASAHIDE HAMAGUCHI, MASAHIRO YAMAZAKI, MICHIAKI FUKUI

Diabetes 2020;69(Supplement_1):463-P

https://doi.org/10.2337/db20-463-P

Published: 01 June 2020

View article titled, 463-P: Deterioration of Atherosclerosis via Dysbiosis in ApoE Null Mice Fed with High-Salt Diet

Meeting Abstracts

1809-P: Liver Pyruvate Carboxylase Knockout Mice Suggest Noncanonical Sources of Acetyl-CoA for Hepatic Lipid Synthesis

MELISSA MAE R. INIGO, STANISLAW DEJA, BLANKA KUCEJOVA, JUSTIN A. FLETCHER, XIAORONG FU, SHAWN C. BURGESS

Diabetes 2020;69(Supplement_1):1809-P

https://doi.org/10.2337/db20-1809-P

Published: 01 June 2020

View article titled, 1809-P: Liver Pyruvate Carboxylase Knockout Mice Suggest Noncanonical Sources of Acetyl-CoA for Hepatic Lipid Synthesis

Meeting Abstracts

1814-P: JAZF1 Knockout Mice Are Protected against Diet-Induced Metabolic Syndrome

CHITRANGDA SRIVASTAVA, KERRY DORR, SARA GRIMM, LAURA M. DEGRAFF, ARTIOM GRUZDEV, ANTON M. JETTEN

Diabetes 2020;69(Supplement_1):1814-P

https://doi.org/10.2337/db20-1814-P

Published: 01 June 2020

View article titled, 1814-P: JAZF1 Knockout Mice Are Protected against Diet-Induced Metabolic Syndrome

Meeting Abstracts

1753-P: Insulin Sensitivity in Long-Lived Growth Hormone–Releasing Hormone Knockout Mice

FANG ZHANG, MERT ICYUZ, LIOU SUN

Diabetes 2020;69(Supplement_1):1753-P

https://doi.org/10.2337/db20-1753-P

Published: 01 June 2020

View article titled, 1753-P: Insulin Sensitivity in Long-Lived Growth Hormone–Releasing Hormone Knockout Mice

Meeting Abstracts

214-LB: Brain Mitochondrial Function and Cognition Are Impaired in Brain Insulin Receptor Knockout Mice

MARK W. PATAKY, GREGORY RUEGSEGGER, KATHERINE KLAUS, PHILLIP STARSKI, K. SREEKUMARAN NAIR

Diabetes 2020;69(Supplement_1):214-LB

https://doi.org/10.2337/db20-214-LB

Published: 01 June 2020

View article titled, 214-LB: Brain Mitochondrial Function and Cognition Are Impaired in Brain Insulin Receptor Knockout Mice

Journal Articles

In This Issue of Diabetes

Diabetes 2020;69(6):1085–1086

https://doi.org/10.2337/db20-ti06

Published: 14 May 2020

View article titled, In This Issue of <em>Diabetes</em>

Meeting Abstracts

2195-P: Identification of the Regulatory Mechanism of mTORC1 Signaling Activity in Pancreatic Beta Cells in GCN2 Knockout Mice

MICHIYO KUDO, SHUN-ICHIRO ASAHARA, AYUMI KANNO, YOSHIAKI KIDO

Diabetes 2019;68(Supplement_1):2195-P

https://doi.org/10.2337/db19-2195-P

Published: 01 June 2019

View article titled, 2195-P: Identification of the Regulatory Mechanism of mTORC1 Signaling Activity in Pancreatic Beta Cells in GCN2 Knockout Mice

Journal Articles

Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production

Zhuo Mao, Hui Lin, Wen Su, Jinghui Li, Minsi Zhou, Zhuoran Li, Beibei Zhou, Qing Yang, Mingyan Zhou, Ke Pan, Jinhan He, Weizhen Zhang

Diabetes 2019;68(6):1197–1209

https://doi.org/10.2337/db18-1321

Published: 01 April 2019

View article titled, Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production

Includes: Supplementary data

Meeting Abstracts

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) Knockout Mice Exhibits Hepatosteatosis Mediated by Enhanced Cd36 Hepatic Expression as a Result of Hyperinsulinemia

SUNIL KUMAR, THOMAS PALAIA, CHRIS HALL, JENNY LEE, MATTHEW STEVENSON, LOUIS RAGOLIA

Diabetes 2018;67(Supplement_1):39-LB

https://doi.org/10.2337/db18-39-LB

Published: 01 July 2018

View article titled, Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) Knockout Mice Exhibits Hepatosteatosis Mediated by Enhanced Cd36 Hepatic Expression as a Result of Hyperinsulinemia

Meeting Abstracts

Altered Gonadal Fat Stromal Cell Populations in Adipocyte-Specific Oncostatin M Receptor Knockout Mice—A Possible Role for Local SDF1

CARRIE M. ELKS

Diabetes 2018;67(Supplement_1):230-LB

https://doi.org/10.2337/db18-230-LB

Published: 01 July 2018

View article titled, Altered Gonadal Fat Stromal Cell Populations in Adipocyte-Specific Oncostatin M Receptor Knockout Mice—A Possible Role for Local SDF1

NARROW

1855-PUB: Generation and Identification of Pik3r3 Gene Pancreatic Beta-Cell Knockout Mice Model

1608-P: Phenotype of Liver-Specific MC3R Knockout Mice

1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

1447-P: The Snd1 Coregulator Controls ß-Cell Function

204-OR: The Chd4 Helicase Modulates ß-Cell Function In Vivo

207-LB: Simultaneous 2H/13C Assessment of Liver and Kidney Metabolic Fluxes Reveals Reciprocal Upregulation of Renal Gluconeogenesis in Hepatic PEPCK-C Knockout Mice

1149-P: A Comparison between One Month vs. Two Months on a High-Fat Diet on the Impact on Glucose Metabolism in Male and Female Liver Androgen Receptor Knockout Mice

1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice

DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation

463-P: Deterioration of Atherosclerosis via Dysbiosis in ApoE Null Mice Fed with High-Salt Diet

1809-P: Liver Pyruvate Carboxylase Knockout Mice Suggest Noncanonical Sources of Acetyl-CoA for Hepatic Lipid Synthesis

1814-P: JAZF1 Knockout Mice Are Protected against Diet-Induced Metabolic Syndrome

1753-P: Insulin Sensitivity in Long-Lived Growth Hormone–Releasing Hormone Knockout Mice

214-LB: Brain Mitochondrial Function and Cognition Are Impaired in Brain Insulin Receptor Knockout Mice

In This Issue of Diabetes

2195-P: Identification of the Regulatory Mechanism of mTORC1 Signaling Activity in Pancreatic Beta Cells in GCN2 Knockout Mice

Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) Knockout Mice Exhibits Hepatosteatosis Mediated by Enhanced Cd36 Hepatic Expression as a Result of Hyperinsulinemia

Altered Gonadal Fat Stromal Cell Populations in Adipocyte-Specific Oncostatin M Receptor Knockout Mice—A Possible Role for Local SDF1

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