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Journal Articles

The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton, Michael W. Schwartz
Journal: Diabetes
Diabetes 2019;68(5):1054–1061
https://doi.org/10.2337/db19-0025
Published: 22 February 2019
View article titled, The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1
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Journal Articles

CRISPR-Cas9–Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes

Xiaotian Lin, Stephane Pelletier, Sebastien Gingras, Stephanie Rigaud, Christian J. Maine, Kristi Marquardt, Yang D. Dai, Karsten Sauer, Alberto R. Rodriguez, Greg Martin, Sergey Kupriyanov, Ling Jiang, Liping Yu, Douglas R. Green, Linda A. Sherman
Journal: Diabetes
Diabetes 2016;65(8):2134–2138
https://doi.org/10.2337/db16-0061
Published: 26 April 2016
View article titled, CRISPR-Cas9–Mediated Modification of the NOD Mouse Genome With <em>Ptpn22<sup>R619W</sup></em> Mutation Increases Autoimmune Diabetes
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Includes: Supplementary data
Journal Articles

Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction

Philip T. Pauerstein, Takuya Sugiyama, Susan E. Stanley, Graeme W. McLean, Jing Wang, Martín G. Martín, Seung K. Kim
Journal: Diabetes
Diabetes 2015;64(8):3037–3049
https://doi.org/10.2337/db15-0042
Published: 21 April 2015
View article titled, Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction
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Journal Articles

Orexinergic Activation of Medullary Premotor Neurons Modulates the Adrenal Sympathoexcitation to Hypothalamic Glucoprivation

Willian S. Korim, Lama Bou Farah, Simon McMullan, Anthony J.M. Verberne
Journal: Diabetes
Diabetes 2014;63(6):1895–1906
https://doi.org/10.2337/db13-1073
Published: 15 May 2014
View article titled, Orexinergic Activation of Medullary Premotor Neurons Modulates the Adrenal Sympathoexcitation to Hypothalamic Glucoprivation
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Includes: Supplementary data
Journal Articles

Role of Synaptic Plasticity and EphA5-EphrinA5 Interaction Within the Ventromedial Hypothalamus in Response to Recurrent Hypoglycemia

Barbara Szepietowska, Tamas L. Horvath, Robert S. Sherwin
Journal: Diabetes
Diabetes 2014;63(3):1140–1147
https://doi.org/10.2337/db13-1259
Published: 13 February 2014
View article titled, Role of Synaptic Plasticity and EphA5-EphrinA5 Interaction Within the Ventromedial Hypothalamus in Response to Recurrent Hypoglycemia
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Journal Articles

EphA5-EphrinA5 Interactions Within the Ventromedial Hypothalamus Influence Counterregulatory Hormone Release and Local Glutamine/Glutamate Balance During Hypoglycemia

Barbara Szepietowska, Wanling Zhu, Jan Czyzyk, Tore Eid, Robert S. Sherwin
Journal: Diabetes
Diabetes 2013;62(4):1282–1288
https://doi.org/10.2337/db12-0982
Published: 14 March 2013
View article titled, EphA5-EphrinA5 Interactions Within the Ventromedial Hypothalamus Influence Counterregulatory Hormone Release and Local Glutamine/Glutamate Balance During Hypoglycemia
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Journal Articles

Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia

Barbara Szepietowska, Wanling Zhu, Owen Chan, Adam Horblitt, James Dziura, Robert S. Sherwin
Journal: Diabetes
Diabetes 2011;60(12):3154–3158
https://doi.org/10.2337/db11-0432
Published: 13 November 2011
View article titled, Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia
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Journal Articles

Increased GABAergic Tone in the Ventromedial Hypothalamus Contributes to Suppression of Counterregulatory Reponses After Antecedent Hypoglycemia

Owen Chan, Haiying Cheng, Raimund Herzog, Daniel Czyzyk, Wanling Zhu, Ajin Wang, Rory J. McCrimmon, Margretta R. Seashore, Robert S. Sherwin
Journal: Diabetes
Diabetes 2008;57(5):1363–1370
https://doi.org/10.2337/db07-1559
Published: 01 May 2008
View article titled, Increased GABAergic Tone in the Ventromedial Hypothalamus Contributes to Suppression of Counterregulatory Reponses After Antecedent Hypoglycemia
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Includes: Supplementary data
Journal Articles

Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia

Rory J. McCrimmon, Margaret Shaw, Xiaoning Fan, Haiying Cheng, Yuyan Ding, Monica C. Vella, Ligang Zhou, Ewan C. McNay, Robert S. Sherwin
Journal: Diabetes
Diabetes 2008;57(2):444–450
https://doi.org/10.2337/db07-0837
Published: 01 February 2008
View article titled, Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia
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Journal Articles

ATP-Sensitive K+ Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia

Owen Chan, Marcus Lawson, Wanling Zhu, Joseph Lee Beverly, Robert S. Sherwin
Journal: Diabetes
Diabetes 2007;56(4):1120–1126
https://doi.org/10.2337/db06-1102
Published: 01 April 2007
View article titled, ATP-Sensitive K<sup>+</sup> Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia
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Journal Articles

Activation of AMP-Activated Protein Kinase Within the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses in Rats With Defective Counterregulation

Rory J. McCrimmon, Xiaoning Fan, Haiying Cheng, Ewan McNay, Owen Chan, Margaret Shaw, Yuyan Ding, Wanling Zhu, Robert S. Sherwin
Journal: Diabetes
Diabetes 2006;55(6):1755–1760
https://doi.org/10.2337/db05-1359
Published: 01 June 2006
View article titled, Activation of AMP-Activated Protein Kinase Within the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses in Rats With Defective Counterregulation
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Journal Articles

Activation of ATP-Sensitive K+ Channels in the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses to Hypoglycemia in Normal and Recurrently Hypoglycemic Rats

Rory J. McCrimmon, Mark L. Evans, Xiaoning Fan, Ewan C. McNay, Owen Chan, Yuyan Ding, Wanling Zhu, Dorte X. Gram, Robert S. Sherwin
Journal: Diabetes
Diabetes 2005;54(11):3169–3174
https://doi.org/10.2337/diabetes.54.11.3169
Published: 01 November 2005
View article titled, Activation of ATP-Sensitive K<sup>+</sup> Channels in the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses to Hypoglycemia in Normal and Recurrently Hypoglycemic Rats
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Journal Articles

Potential Role for AMP-Activated Protein Kinase in Hypoglycemia Sensing in the Ventromedial Hypothalamus

Rory J. McCrimmon, Xiaoning Fan, Yuyan Ding, Wanling Zhu, Ralph J. Jacob, Robert S. Sherwin
Journal: Diabetes
Diabetes 2004;53(8):1953–1958
https://doi.org/10.2337/diabetes.53.8.1953
Published: 01 August 2004
View article titled, Potential Role for AMP-Activated Protein Kinase in Hypoglycemia Sensing in the Ventromedial Hypothalamus
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Journal Articles

Dynamic Imaging of Endoplasmic Reticulum Ca2+ Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: Roles of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2 and Ryanodine Receptors

Aniko Varadi, Guy A. Rutter
Journal: Diabetes
Diabetes 2002;51(suppl_1):S190–S201
https://doi.org/10.2337/diabetes.51.2007.S190
Published: 01 February 2002
View article titled, Dynamic Imaging of Endoplasmic Reticulum Ca<sup>2+</sup> Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: <subtitle>Roles of Sarco(endo)plasmic Reticulum Ca<sup>2+</sup>-ATPase (SERCA)-2 and Ryanodine Receptors </subtitle>
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Meeting Abstracts

Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats.

Y Minokoshi, M S Haque, T Shimazu
Journal: Diabetes
Diabetes 1999;48(2):287–291
https://doi.org/10.2337/diabetes.48.2.287
Published: 01 February 1999
View article titled, Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats.
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Journal Articles

The Effect of Leptin Is Enhanced by Microinjection Into the Ventromedial Hypothalamus

Ralph J Jacob, James Dziura, Matthew B Medwick, Paola Leone, Sonia Caprio, Matthew During, Gerald I Shulman, Robert Sherwin
Journal: Diabetes
Diabetes 1997;46(1):150–152
https://doi.org/10.2337/diab.46.1.150
Published: 01 January 1997
View article titled, The Effect of Leptin Is Enhanced by Microinjection Into the Ventromedial Hypothalamus
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