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Journal Articles

An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians

Sascha Heinitz, Michael Traurig, Jonathan Krakoff, Philipp Rabe, Claudia Stäubert, Sayuko Kobes, Robert L. Hanson, Michael Stumvoll, Matthias Blüher, Clifton Bogardus, Leslie Baier, Paolo Piaggi
Journal: Diabetes
Diabetes 2024;73(8):1361–1371
https://doi.org/10.2337/db23-0690
Published: 22 May 2024
View article titled, An E115A Missense Variant in <em>CERS2</em> Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians
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Journal Articles

Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance

Soyoung Park, Hye-Na Cha, Min-Gyeong Shin, Sanghee Park, Yeongmin Kim, Min-Seob Kim, Kyung-Hoon Shin, Themis Thoudam, Eun Ju Lee, Robert R. Wolfe, Jinmyoung Dan, Jin-Ho Koh, Il-Young Kim, Inho Choi, In-Kyu Lee, Hoon-Ki Sung, So-Young Park
Journal: Diabetes
Diabetes 2024;73(7):1084–1098
https://doi.org/10.2337/db23-0432
Published: 24 April 2024
View article titled, Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance
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Journal Articles

Glucose Regulation of β-Cell KATP Channels: Is a New Model Needed?

Guy A. Rutter, Ian R. Sweet
Journal: Diabetes
Diabetes 2024;73(6):849–855
https://doi.org/10.2337/dbi23-0031
Published: 19 April 2024
View article titled, Glucose Regulation of β-Cell K<sub>ATP</sub> Channels: Is a New Model Needed?
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Journal Articles

Do We Need a New Hypothesis for KATP Closure in β-Cells? Distinguishing the Baby From the Bathwater

Leslie Sherwin Satin, Jeremías Corradi, Arthur Stewart Sherman
Journal: Diabetes
Diabetes 2024;73(6):844–848
https://doi.org/10.2337/db24-0131
Published: 19 April 2024
View article titled, Do We Need a New Hypothesis for K<sub>ATP</sub> Closure in β-Cells? Distinguishing the Baby From the Bathwater
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Journal Articles

Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model!

Matthew J. Merrins, Richard G. Kibbey
Journal: Diabetes
Diabetes 2024;73(6):856–863
https://doi.org/10.2337/dbi23-0032
Published: 19 April 2024
View article titled, Glucose Regulation of β-Cell K<sub>ATP</sub> Channels: It Is Time for a New Model!
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Journal Articles

Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults With Diabetes

Sofhia V. Ramos, Giovanna Distefano, Li-Yung Lui, Peggy M. Cawthon, Philip Kramer, Ian J. Sipula, Fiona M. Bello, Theresa Mau, Michael J. Jurczak, Anthony J. Molina, Erin E. Kershaw, David J. Marcinek, Eric Shankland, Frederico G.S. Toledo, Anne B. Newman, Russell T. Hepple, Stephen B. Kritchevsky, Bret H. Goodpaster, Steven R. Cummings, Paul M. Coen
Journal: Diabetes
Diabetes 2024;73(7):1048–1057
https://doi.org/10.2337/db23-0827
Published: 29 March 2024
View article titled, Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults With Diabetes
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Journal Articles

CPT1A Protects Podocytes From Lipotoxicity and Apoptosis In Vitro and Alleviates Diabetic Nephropathy In Vivo

Yajuan Xie, Qian Yuan, Ben Tang, Yaru Xie, Yiling Cao, Yang Qiu, Jieyu Zeng, Zhiwen Wang, Hua Su, Chun Zhang
Journal: Diabetes
Diabetes 2024;73(6):879–895
https://doi.org/10.2337/db23-0811
Published: 20 March 2024
View article titled, CPT1A Protects Podocytes From Lipotoxicity and Apoptosis In Vitro and Alleviates Diabetic Nephropathy In Vivo
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Journal Articles

Metabolic Fluxes in the Renal Cortex Are Dysregulated In Vivo in Response to High-Fat Diet

Clinton M. Hasenour, Deveena R. Banerjee, Jamey D. Young
Journal: Diabetes
Diabetes 2024;73(6):903–908
https://doi.org/10.2337/db23-0710
Published: 19 March 2024
View article titled, Metabolic Fluxes in the Renal Cortex Are Dysregulated In Vivo in Response to High-Fat Diet
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Journal Articles

Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology

Lisa C. Heather, Keshav Gopal, Nikola Srnic, John R. Ussher
Journal: Diabetes
Diabetes 2024;73(5):659–670
https://doi.org/10.2337/dbi23-0019
Published: 22 February 2024
View article titled, Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology
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Journal Articles

A New Mitochondrial Uncoupler Improves Metabolic Homeostasis in Mice

Gautham Ramshankar, Rachel J. Perry
Journal: Diabetes
Diabetes 2024;73(3):357–358
https://doi.org/10.2337/dbi23-0033
Published: 20 February 2024
View article titled, A New Mitochondrial Uncoupler Improves Metabolic Homeostasis in Mice
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Journal Articles

Mitochondrial Dynamics, Diabetes, and Cardiovascular Disease

Luis Miguel García-Peña, E. Dale Abel, Renata O. Pereira
Journal: Diabetes
Diabetes 2024;73(2):151–161
https://doi.org/10.2337/dbi23-0003
Published: 19 January 2024
View article titled, Mitochondrial Dynamics, Diabetes, and Cardiovascular Disease
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Journal Articles

Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Mi Huang, Rashmi B. Prasad, Daniel E. Coral, Line Hjort, Daniel T.R. Minja, Hindrik Mulder, Paul W. Franks, Sebastian Kalamajski
Journal: Diabetes
Diabetes 2024;73(4):637–645
https://doi.org/10.2337/db23-0531
Published: 08 January 2024
View article titled, Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates <em>PPARGC1B</em> Expression, and Alters Brown Adipocyte Function
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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD
Journal: Diabetes
Diabetes 2024;73(1):1–2
https://doi.org/10.2337/db24-ti01
Published: 20 December 2023
View article titled, In This Issue of <em>Diabetes</em>
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Journal Articles

PTPN2 Regulates Metabolic Flux to Affect β-Cell Susceptibility to Inflammatory Stress

Yong Kyung Kim, Youngjung Rachel Kim, Kristen L. Wells, Dylan Sarbaugh, Michelle Guney, Chia-Feng Tsai, Tiffany Zee, Gerard Karsenty, Ernesto S. Nakayasu, Lori Sussel
Journal: Diabetes
Diabetes 2024;73(3):434–447
https://doi.org/10.2337/db23-0355
Published: 28 November 2023
View article titled, PTPN2 Regulates Metabolic Flux to Affect β-Cell Susceptibility to Inflammatory Stress
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Journal Articles

Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice

Martina Beretta, Yumin Dai, Ellen M. Olzomer, Calum S. Vancuylenburg, José A. Santiago-Rivera, Ashleigh M. Philp, Stefan R. Hargett, Keyong Li, Divya P. Shah, Sing-Young Chen, Stephanie J. Alexopoulos, Catherine Li, Thurl E. Harris, Brendan Lee, Michel Wathier, Jennifer M. Cermak, Simon P. Tucker, Nigel Turner, Douglas A. Bayliss, Andrew Philp, Frances L. Byrne, Webster L. Santos, Kyle L. Hoehn
Journal: Diabetes
Diabetes 2024;73(3):374–384
https://doi.org/10.2337/db23-0233
Published: 23 October 2023
View article titled, Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice
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Journal Articles

Dissecting the Roles of the Nuclear and Mitochondrial Genomes in a Mouse Model of Autoimmune Diabetes

Weiwei Zou, Janaki Chezhian, Tenghui Yu, Wensheng Liu, Jimmy Vu, Jesse Slone, Taosheng Huang
Journal: Diabetes
Diabetes 2024;73(1):108–119
https://doi.org/10.2337/db23-0430
Published: 17 October 2023
View article titled, Dissecting the Roles of the Nuclear and Mitochondrial Genomes in a Mouse Model of Autoimmune Diabetes
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Journal Articles

Obesity Enables NLRP3 Activation and Induces Myocardial Fibrosis via Hyperacetylation of HADHa

Yan Deng, Xin Liu, Min Xie, Rui Zhao, Liwei Ji, Kuo Tang, Wei Yang, Wei Ou, Maodi Xie, Tao Li
Journal: Diabetes
Diabetes 2023;72(11):1597–1608
https://doi.org/10.2337/db23-0264
Published: 25 August 2023
View article titled, Obesity Enables NLRP3 Activation and Induces Myocardial Fibrosis via Hyperacetylation of HADHa
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Journal Articles

A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice

Anna L. Lang, Nadee Nissanka, Ruy A. Louzada, Alejandro Tamayo, Elizabeth Pereira, Carlos T. Moraes, Alejandro Caicedo
Journal: Diabetes
Diabetes 2023;72(9):1262–1276
https://doi.org/10.2337/db22-0728
Published: 21 June 2023
View article titled, A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice
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Meeting Abstracts

275-LB: Mitochondrial Fission Factor Can Be a Key Factor in the Regulation of Hepatic Lipid Metabolism

YUKINA TAKEICHI, TAKASHI MIYAZAWA, YOSHIHIRO OGAWA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):275-LB
https://doi.org/10.2337/db23-275-LB
Published: 20 June 2023
View article titled, 275-LB: Mitochondrial Fission Factor Can Be a Key Factor in the Regulation of Hepatic Lipid Metabolism
Meeting Abstracts

75-OR: Cold-Responsive Proteolytic Rewiring of Mitochondria Safeguards White Fat Thermogenic Remodeling

TINGTING FU, WANPING SUN, ZHENG ZHOU, ZHISHENG XU, MAO YAN, LIKUN YANG, YUJING YIN, ZHENJI GAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):75-OR
https://doi.org/10.2337/db23-75-OR
Published: 20 June 2023
View article titled, 75-OR: Cold-Responsive Proteolytic Rewiring of Mitochondria Safeguards White Fat Thermogenic Remodeling