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Journal Articles

Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes

Yong Lin, Jelena Perovanovic, Yuelin Kong, Botond Z. Igyarto, Sandra Zurawski, Dean Tantin, Gerard Zurawski, Maria Bettini, Matthew L. Bettini

Diabetes 2022;71(8):1735–1745

DOI: https://doi.org/10.2337/db21-1069

Published: 21 August 2022

View article titled, Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes

Meeting Abstracts

673-P: Successful Use of Dexcom G6 in Neonate with SGA and Chromosome 6q24-Related Transient Neonatal Diabetes Mellitus

EVAN A. LOS, EVELYN ARTZ, CASSANDRA SAUNDERS, KAITLYN WISE, JOHN WELSH

Diabetes 2022;71(Supplement_1):673-P

DOI: https://doi.org/10.2337/db22-673-P

Published: 01 June 2022

View article titled, 673-P: Successful Use of Dexcom G6 in Neonate with SGA and Chromosome 6q24-Related Transient Neonatal Diabetes Mellitus

Meeting Abstracts

1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

JINCY IMMANUEL, GERNOT DESOYE, MIREILLE VANPOPPEL, ALEXANDRA KAUTZKY-WILLER, ROSA CORCOY, ALESSANDRA BERTOLOTTO, FIDELMA P. DUNNE, JÜRGEN HARREITER, LISE LOTTE TORVIN ANDERSEN, DORTE M. JENSEN, ELISABETH R. MATHIESEN, DAVID J. HILL, PETER DAMM, FRANK J. SNOEK, JUAN M. ADELANTADO, EWA WENDER-OZEGOWSKA, DAVID SIMMONS

Diabetes 2022;71(Supplement_1):1045-P

DOI: https://doi.org/10.2337/db22-1045-P

Published: 01 June 2022

View article titled, 1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

Meeting Abstracts

248-LB: Nrf2 Is Essential for Expanding Neonatal Pancreatic Beta-Cell Mass

SHARON BAUMEL-ALTERZON, ADOLFO GARCIA-OCANA, DONALD SCOTT

Diabetes 2022;71(Supplement_1):248-LB

DOI: https://doi.org/10.2337/db22-248-LB

Published: 01 June 2022

View article titled, 248-LB: Nrf2 Is Essential for Expanding Neonatal Pancreatic Beta-Cell Mass

Meeting Abstracts

246-LB: Neonatal Microbes Stimulate Beta-Cell Development

JENNIFER H. HILL, KAREN GUILLEMIN, CHARLES L. MURTAUGH, JUNE ROUND

Diabetes 2022;71(Supplement_1):246-LB

DOI: https://doi.org/10.2337/db22-246-LB

Published: 01 June 2022

View article titled, 246-LB: Neonatal Microbes Stimulate Beta-Cell Development

Journal Articles

YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

Di Liu, Kevin Y. Yang, Vicken W. Chan, Wenchu Ye, Charing C.N. Chong, Chi Chiu Wang, Huating Wang, Bin Zhou, Kenneth K.Y. Cheng, Kathy O. Lui

Diabetes 2022;71(5):961–977

DOI: https://doi.org/10.2337/db21-0695

Published: 03 February 2022

View article titled, YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

Journal Articles

Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Diabetes 2022;71(4):821–836

DOI: https://doi.org/10.2337/db21-0479

Published: 21 January 2022

View article titled, Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Meeting Abstracts

943-P: Glycated Albumin as a Predictor of Adverse Neonatal Events in Pregnant Women with Diabetes

JENNIFER L. POWERS CARSON, EBONY B. CARTER

Diabetes 2021;70(Supplement_1):943-P

DOI: https://doi.org/10.2337/db21-943-P

Published: 01 June 2021

View article titled, 943-P: Glycated Albumin as a Predictor of Adverse Neonatal Events in Pregnant Women with Diabetes

Meeting Abstracts

79-LB: Pharmacokinetics and Pharmacodynamics of Avexitide (Exendin 9-39) in Neonates and Infants with Congenital Hyperinsulinism

COLLEEN CRAIG, DIVA D. DE LEON

Diabetes 2021;70(Supplement_1):79-LB

DOI: https://doi.org/10.2337/db21-79-LB

Published: 01 June 2021

View article titled, 79-LB: Pharmacokinetics and Pharmacodynamics of Avexitide (Exendin 9-39) in Neonates and Infants with Congenital Hyperinsulinism

Meeting Abstracts

164-LB: Association of Maternal Insulin Sensitivity during Gestation and Neonatal Size

SAYALI DESHPANDE-JOSHI, HEMANT DAMLE, MADHURA K. DESHMUKH, DATTATRAY BHAT, NILAM S. MEMANE, ABOLI A. BHALERAO, RASIKA LADKAT, PRADEEP TIWARI, SUHAS R. OTIV, OTILIA PERICHART-PERERA, MIREILLE VAN POPPEL, CHRISTINA A. VINTER, DORTE M. JENSEN, GERNOT DESOYE, PATRICK CATALANO, CHITTARANJAN S. YAJNIK

Diabetes 2021;70(Supplement_1):164-LB

DOI: https://doi.org/10.2337/db21-164-LB

Published: 01 June 2021

View article titled, 164-LB: Association of Maternal Insulin Sensitivity during Gestation and Neonatal Size

Journal Articles

De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction

Elisa De Franco, Richard Caswell, Matthew B. Johnson, Matthew N. Wakeling, Amnon Zung, Vũ Chí Dũng, Cấn Thị Bích Ngọc, Rajiv Goonetilleke, Maritza Vivanco Jury, Mohammed El-Khateeb, Sian Ellard, Sarah E. Flanagan, David Ron, Andrew T. Hattersley

Diabetes 2020;69(3):477–483

DOI: https://doi.org/10.2337/db19-1029

Published: 27 December 2020

View article titled, De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction

Meeting Abstracts

97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

TERI L. HERNANDEZ, SARAH S. FARABI, JARON ARBET, NICOLE HIRSCH, EMILY Z. DUNN, KRISTY P. HEISS, JAYNE MARTIN CARLI, NANCY F. KREBS, THERESA L. POWELL, REGINA REYNOLDS, RACHAEL E. VAN PELT, JACOB E. FRIEDMAN, LINDA (LYNN) A. BARBOUR

Diabetes 2020;69(Supplement_1):97-OR

DOI: https://doi.org/10.2337/db20-97-OR

Published: 01 June 2020

View article titled, 97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

Meeting Abstracts

1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

TAKAO TAKIYAMA, RYOICHI BESSHO, KAZUKI SAWAMOTO, YUMI TAKIYAMA

Diabetes 2020;69(Supplement_1):1845-P

DOI: https://doi.org/10.2337/db20-1845-P

Published: 01 June 2020

View article titled, 1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

Meeting Abstracts

1801-P: Novel De Novo INS P.T97P Variant Presenting with Severe Neonatal DKA

RAYHAN LAL, HANNAH P. MOELLER, RAQUEL FREEMAN, PRIYA PRAHALAD, JUSTIN P. ANNES

Diabetes 2020;69(Supplement_1):1801-P

DOI: https://doi.org/10.2337/db20-1801-P

Published: 01 June 2020

View article titled, 1801-P: Novel De Novo INS P.T97P Variant Presenting with Severe Neonatal DKA

Meeting Abstracts

194-OR: Impaired Awareness of Hypoglycemia and Maternal/Neonatal Outcomes in the CONCEPTT Trial

JASMINE BAHRAMI, GEORGE TOMLINSON, HELEN R. MURPHY, DENICE FEIG

Diabetes 2020;69(Supplement_1):194-OR

DOI: https://doi.org/10.2337/db20-194-OR

Published: 01 June 2020

View article titled, 194-OR: Impaired Awareness of Hypoglycemia and Maternal/Neonatal Outcomes in the CONCEPTT Trial

Meeting Abstracts

1958-P: Neonatal Il-4 Induces a Persistent Decrease in Adipocyte Maturation

TAMMY YING, PATRICK SEALE, REBECCA A. SIMMONS

Diabetes 2020;69(Supplement_1):1958-P

DOI: https://doi.org/10.2337/db20-1958-P

Published: 01 June 2020

View article titled, 1958-P: Neonatal Il-4 Induces a Persistent Decrease in Adipocyte Maturation

Meeting Abstracts

1245-P: Maternal HbA1c Is Related to Childhood Fat Mass and Only Partially Mediated by Neonatal Fat Mass

ELLEN C. FRANCIS, BRANDY RINGHAM, DEBORAH H. GLUECK, WEI PERNG, DANA DABELEA

Diabetes 2020;69(Supplement_1):1245-P

DOI: https://doi.org/10.2337/db20-1245-P

Published: 01 June 2020

View article titled, 1245-P: Maternal HbA1c Is Related to Childhood Fat Mass and Only Partially Mediated by Neonatal Fat Mass

Meeting Abstracts

1388-P: Maternal and Neonatal Outcomes in Pregnancies with Preexisting Type 1 Diabetes and Controls

RAVINDER JEET KAUR, SHAFAQ RAZA RIZVI, MARI CHARISSE TRINIDAD, BYRON H. SMITH, SREEDHAR BATTHULA, SHELLY K. MCCRADY-SPITZER, COREY REID, DONNA DESJARDINS, GRENYE O’MALLEY, KRISTIN N. CASTORINO, JORDAN E. PINSKER, WALTER K. KREMERS, EYAL DASSAU, CAROL J. LEVY, YOGISH C. KUDVA

Diabetes 2020;69(Supplement_1):1388-P

DOI: https://doi.org/10.2337/db20-1388-P

Published: 01 June 2020

View article titled, 1388-P: Maternal and Neonatal Outcomes in Pregnancies with Preexisting Type 1 Diabetes and Controls

Meeting Abstracts

1382-P: Does Tight Gestational Diabetes Mellitus Control Have an Impact on the Maternal and Neonatal Outcome Compared with General Populations? Which Factors Predict the Adverse Pregnancy Outcomes?

PETROS THOMAKOS, OLGA KEPAPTSOGLOU, CAROL BARRETO, ANASTASIA TROUVA, DIMITRIS TROUVAS, CHRISTOS S.P. ZOUPAS

Diabetes 2020;69(Supplement_1):1382-P

DOI: https://doi.org/10.2337/db20-1382-P

Published: 01 June 2020

View article titled, 1382-P: Does Tight Gestational Diabetes Mellitus Control Have an Impact on the Maternal and Neonatal Outcome Compared with General Populations? Which Factors Predict the Adverse Pregnancy Outcomes?

Journal Articles

Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions

Yan-Ting Chen, Yun Hu, Qi-Yuan Yang, Jun Seok Son, Xiang-Dong Liu, Jeanene M. de Avila, Mei-Jun Zhu, Min Du

Diabetes 2020;69(8):1662–1674

DOI: https://doi.org/10.2337/db20-0009

Published: 14 May 2020

View article titled, Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions

NARROW

Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes

673-P: Successful Use of Dexcom G6 in Neonate with SGA and Chromosome 6q24-Related Transient Neonatal Diabetes Mellitus

1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

248-LB: Nrf2 Is Essential for Expanding Neonatal Pancreatic Beta-Cell Mass

246-LB: Neonatal Microbes Stimulate Beta-Cell Development

YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

943-P: Glycated Albumin as a Predictor of Adverse Neonatal Events in Pregnant Women with Diabetes

79-LB: Pharmacokinetics and Pharmacodynamics of Avexitide (Exendin 9-39) in Neonates and Infants with Congenital Hyperinsulinism

164-LB: Association of Maternal Insulin Sensitivity during Gestation and Neonatal Size

De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction

97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

1801-P: Novel De Novo INS P.T97P Variant Presenting with Severe Neonatal DKA

194-OR: Impaired Awareness of Hypoglycemia and Maternal/Neonatal Outcomes in the CONCEPTT Trial

1958-P: Neonatal Il-4 Induces a Persistent Decrease in Adipocyte Maturation

1245-P: Maternal HbA1c Is Related to Childhood Fat Mass and Only Partially Mediated by Neonatal Fat Mass

1388-P: Maternal and Neonatal Outcomes in Pregnancies with Preexisting Type 1 Diabetes and Controls

1382-P: Does Tight Gestational Diabetes Mellitus Control Have an Impact on the Maternal and Neonatal Outcome Compared with General Populations? Which Factors Predict the Adverse Pregnancy Outcomes?

Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions

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