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Meeting Abstracts

260-LB: Elucidating the Role of NTPDase3 and Purinergic Signaling in Islet Hormone Secretion

TIFFANY M. RICHARDSON, CHUNHUA DAI, RADHIKA ARAMANDLA, HEATHER H. DURAI, CONRAD REIHSMANN, COREY DAVIS, SHAOJUN MEI, DANNIELLE GIBSON, SHRISTI SHRESTHA, DIANE C. SAUNDERS, KATIE C. COATE, SIMON C. ROBSON, ALVIN C. POWERS, MARCELA BRISSOVA

Diabetes 2022;71(Supplement_1):260-LB

https://doi.org/10.2337/db22-260-LB

Published: 01 June 2022

View article titled, 260-LB: Elucidating the Role of NTPDase3 and Purinergic Signaling in Islet Hormone Secretion

Meeting Abstracts

1242-P: Defining the Nkx6.1 Interactome in Beta Cells Reveals a Novel Interaction with Pdx1

CONNOR C. LITTLEFIELD, NATHANAEL C. JENSEN, JONATHON T. HILL, JOHN C. PRICE, JEFFERY S. TESSEM

Diabetes 2021;70(Supplement_1):1242-P

https://doi.org/10.2337/db21-1242-P

Published: 01 June 2021

View article titled, 1242-P: Defining the Nkx6.1 Interactome in Beta Cells Reveals a Novel Interaction with Pdx1

Journal Articles

Nucleotides Released From Palmitate-Challenged Muscle Cells Through Pannexin-3 Attract Monocytes

Nicolas J. Pillon, Yujin E. Li, Lisbeth N. Fink, Joseph T. Brozinick, Alexander Nikolayev, Ming-Shang Kuo, Philip J. Bilan, Amira Klip

Diabetes 2014;63(11):3815–3826

https://doi.org/10.2337/db14-0150

Published: 13 October 2014

View article titled, Nucleotides Released From Palmitate-Challenged Muscle Cells Through Pannexin-3 Attract Monocytes

Includes: Supplementary data

Journal Articles

Molecular Mechanism of Sulphonylurea Block of K_ATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes

Peter Proks, Heidi de Wet, Frances M. Ashcroft

Diabetes 2013;62(11):3909–3919

https://doi.org/10.2337/db13-0531

Published: 18 October 2013

View article titled, Molecular Mechanism of Sulphonylurea Block of KATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes

Journal Articles

Mutations of the Same Conserved Glutamate Residue in NBD2 of the Sulfonylurea Receptor 1 Subunit of the K_ATP Channel Can Result in Either Hyperinsulinism or Neonatal Diabetes

Roope Männikkö, Sarah E. Flanagan, Xiuli Sim, David Segal, Khalid Hussain, Sian Ellard, Andrew T. Hattersley, Frances M. Ashcroft

Diabetes 2011;60(6):1813–1822

https://doi.org/10.2337/db10-1583

Published: 21 May 2011

View article titled, Mutations of the Same Conserved Glutamate Residue in NBD2 of the Sulfonylurea Receptor 1 Subunit of the KATP Channel Can Result in Either Hyperinsulinism or Neonatal Diabetes

Includes: Supplementary data

Journal Articles

Attenuated Purinergic Receptor Function in Patients With Type 2 Diabetes

Pia Thaning, Laurids T. Bune, Ylva Hellsten, Henriette Pilegaard, Bengt Saltin, Jaya B. Rosenmeier

Diabetes 2010;59(1):182–189

https://doi.org/10.2337/db09-1068

Published: 06 October 2009

View article titled, Attenuated Purinergic Receptor Function in Patients With Type 2 Diabetes

Journal Articles

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K⁺ Channel

Kevin S.C. Hamming, Daniel Soliman, Laura C. Matemisz, Omid Niazi, Yiqiao Lang, Anna L. Gloyn, Peter E. Light

Diabetes 2009;58(10):2419–2424

https://doi.org/10.2337/db09-0143

Published: 08 July 2009

View article titled, Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel

Journal Articles

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

Keiichi Enjyoji, Ko Kotani, Chandrashekar Thukral, Benjamin Blumel, Xiaofeng Sun, Yan Wu, Masato Imai, David Friedman, Eva Csizmadia, Wissam Bleibel, Barbara B. Kahn, Simon C. Robson

Diabetes 2008;57(9):2311–2320

https://doi.org/10.2337/db07-1265

Published: 01 September 2008

View article titled, Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

Journal Articles

The Vascular Ectonucleotidase ENTPD1 Is a Novel Renoprotective Factor in Diabetic Nephropathy

David J. Friedman, Helmut G. Rennke, Eva Csizmadia, Keiichi Enjyoji, Simon C. Robson

Diabetes 2007;56(9):2371–2379

https://doi.org/10.2337/db06-1593

Published: 01 September 2007

View article titled, The Vascular Ectonucleotidase ENTPD1 Is a Novel Renoprotective Factor in Diabetic Nephropathy

Journal Articles

The Actions of a Novel Potent Islet β-Cell–Specific ATP-Sensitive K⁺ Channel Opener Can Be Modulated by Syntaxin-1A Acting on Sulfonylurea Receptor 1

Betty Ng, Youhou Kang, Chadwick L. Elias, Yan He, Huanli Xie, John B. Hansen, Philip Wahl, Herbert Y. Gaisano

Diabetes 2007;56(8):2124–2134

https://doi.org/10.2337/db07-0030

Published: 01 August 2007

View article titled, The Actions of a Novel Potent Islet β-Cell–Specific ATP-Sensitive K+ Channel Opener Can Be Modulated by Syntaxin-1A Acting on Sulfonylurea Receptor 1

Includes: Supplementary data

Journal Articles

A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM)

Ricard Masia, Diva D. De Leon, Courtney MacMullen, Heather McKnight, Charles A. Stanley, Colin G. Nichols

Diabetes 2007;56(5):1357–1362

https://doi.org/10.2337/db06-1746

Published: 01 May 2007

View article titled, A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM)

Journal Articles

Errata

Diabetes 2006;55(12):3635

https://doi.org/10.2337/db06-er12

Published: 01 December 2006

View article titled, Errata

Journal Articles

ATP Sensitivity of the ATP-Sensitive K⁺ Channel in Intact and Permeabilized Pancreatic β-Cells

Andrei I. Tarasov, Christophe A.J. Girard, Frances M. Ashcroft

Diabetes 2006;55(9):2446–2454

https://doi.org/10.2337/db06-0360

Published: 01 September 2006

View article titled, ATP Sensitivity of the ATP-Sensitive K+ Channel in Intact and Permeabilized Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

Redox Control of Exocytosis: Regulatory Role of NADPH, Thioredoxin, and Glutaredoxin

Rosita Ivarsson, Roel Quintens, Sandra Dejonghe, Katsura Tsukamoto, Peter in ’t Veld, Erik Renström, Frans C. Schuit

Diabetes 2005;54(7):2132–2142

https://doi.org/10.2337/diabetes.54.7.2132

Published: 01 July 2005

View article titled, Redox Control of Exocytosis: <subtitle>Regulatory Role of NADPH, Thioredoxin, and Glutaredoxin</subtitle>

Journal Articles

Identification of a Functionally Important Negatively Charged Residue Within the Second Catalytic Site of the SUR1 Nucleotide-Binding Domains

Jeff D. Campbell, Peter Proks, Jonathan D. Lippiat, Mark S.P. Sansom, Frances M. Ashcroft

Diabetes 2004;53(suppl_3):S123–S127

https://doi.org/10.2337/diabetes.53.suppl_3.S123

Published: 01 December 2004

View article titled, Identification of a Functionally Important Negatively Charged Residue Within the Second Catalytic Site of the SUR1 Nucleotide-Binding Domains

Journal Articles

Toward Linking Structure With Function in ATP-Sensitive K+ Channels

Joseph Bryan, Wanda H. Vila-Carriles, Guiling Zhao, Audrey P. Babenko, Lydia Aguilar-Bryan

Diabetes 2004;53(suppl_3):S104–S112

https://doi.org/10.2337/diabetes.53.suppl_3.S104

Published: 01 December 2004

View article titled, Toward Linking Structure With Function in ATP-Sensitive K+ Channels

Journal Articles

Metabolic Regulation of the Pancreatic Beta-Cell ATP-Sensitive K⁺ Channel: A Pas de Deux

Andrei Tarasov, Julien Dusonchet, Frances Ashcroft

Diabetes 2004;53(suppl_3):S113–S122

https://doi.org/10.2337/diabetes.53.suppl_3.S113

Published: 01 December 2004

View article titled, Metabolic Regulation of the Pancreatic Beta-Cell ATP-Sensitive K+ Channel: <subtitle>A Pas de Deux</subtitle>

Journal Articles

Melanocortin 4 Receptor Gene Variation Is Associated With Severe Obesity in Pima Indians

Lijun Ma, P. Antonio Tataranni, Clifton Bogardus, Leslie J. Baier

Diabetes 2004;53(10):2696–2699

https://doi.org/10.2337/diabetes.53.10.2696

Published: 01 October 2004

View article titled, Melanocortin 4 Receptor Gene Variation Is Associated With Severe Obesity in Pima Indians

Journal Articles

Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes

Hannes Oberkofler, Veronika Linnemayr, Raimund Weitgasser, Kerstin Klein, Mingqiang Xie, Bernhard Iglseder, Franz Krempler, Bernhard Paulweber, Wolfgang Patsch

Diabetes 2004;53(5):1385–1393

https://doi.org/10.2337/diabetes.53.5.1385

Published: 01 May 2004

View article titled, Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes

Includes: Supplementary data

Journal Articles

BETA2 Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells

J. Michael Moates, Sarmistha Nanda, Michelle A. Cissell, Ming-Jer Tsai, Roland Stein

Diabetes 2003;52(2):403–408

https://doi.org/10.2337/diabetes.52.2.403

Published: 01 February 2003

View article titled, BETA2 Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells

NARROW

260-LB: Elucidating the Role of NTPDase3 and Purinergic Signaling in Islet Hormone Secretion

1242-P: Defining the Nkx6.1 Interactome in Beta Cells Reveals a Novel Interaction with Pdx1

Nucleotides Released From Palmitate-Challenged Muscle Cells Through Pannexin-3 Attract Monocytes

Molecular Mechanism of Sulphonylurea Block of K_ATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes

Mutations of the Same Conserved Glutamate Residue in NBD2 of the Sulfonylurea Receptor 1 Subunit of the K_ATP Channel Can Result in Either Hyperinsulinism or Neonatal Diabetes

Attenuated Purinergic Receptor Function in Patients With Type 2 Diabetes

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K⁺ Channel

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

The Vascular Ectonucleotidase ENTPD1 Is a Novel Renoprotective Factor in Diabetic Nephropathy

The Actions of a Novel Potent Islet β-Cell–Specific ATP-Sensitive K⁺ Channel Opener Can Be Modulated by Syntaxin-1A Acting on Sulfonylurea Receptor 1

A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM)

Errata

ATP Sensitivity of the ATP-Sensitive K⁺ Channel in Intact and Permeabilized Pancreatic β-Cells

Redox Control of Exocytosis: Regulatory Role of NADPH, Thioredoxin, and Glutaredoxin

Identification of a Functionally Important Negatively Charged Residue Within the Second Catalytic Site of the SUR1 Nucleotide-Binding Domains

Toward Linking Structure With Function in ATP-Sensitive K+ Channels

Metabolic Regulation of the Pancreatic Beta-Cell ATP-Sensitive K⁺ Channel: A Pas de Deux

Melanocortin 4 Receptor Gene Variation Is Associated With Severe Obesity in Pima Indians

Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes

BETA2 Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells

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