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Journal Articles

β-Cell–Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion

Diabetes 2023;72(8):1112–1126

Published: 22 May 2023

View article titled, β-Cell–Specific <em>E2f1</em> Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion

Meeting Abstracts

300-OR: A Modular Massively Parallel Reporter Assay Uncovers Context-Specific Activity of Diabetes-Associated Regulatory Elements

ADELAIDE TOVAR

Diabetes 2022;71(Supplement_1):300-OR

https://doi.org/10.2337/db22-300-OR

Published: 01 June 2022

View article titled, 300-OR: A Modular Massively Parallel Reporter Assay Uncovers Context-Specific Activity of Diabetes-Associated Regulatory Elements

Journal Articles

Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation

Joji Kusuyama, Nathan S. Makarewicz, Brent G. Albertson, Ana Barbara Alves-Wagner, Royce H. Conlin, Noah B. Prince, Christiano R.R. Alves, Krithika Ramachandran, Chisayo Kozuka, Yang Xiudong, Yang Xia, Michael F. Hirshman, Toshihisa Hatta, Ryoichi Nagatomi, Eva S. Nozik, Laurie J. Goodyear

Diabetes 2022;71(6):1170–1181

https://doi.org/10.2337/db21-0706

Published: 15 March 2022

View article titled, Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation

Meeting Abstracts

1199-P: The Oncogene MDM2 Induces M1 Macrophage Polarization and Adipose Tissue Inflammation in Obesity

KENNETH KING YIP CHENG

Diabetes 2021;70(Supplement_1):1199-P

https://doi.org/10.2337/db21-1199-P

Published: 01 June 2021

View article titled, 1199-P: The Oncogene MDM2 Induces M1 Macrophage Polarization and Adipose Tissue Inflammation in Obesity

Meeting Abstracts

700-P: Mechanism for the Beneficial Effects of Maternal Exercise to Improve Offspring Metabolic Health

JOJI KUSUYAMA, ANA B. WAGNER, ROYCE H. CONLIN, NATHAN S. MAKAREWICZ, MAGNUS MØLLER, EMILY M. MIELE, ROELAND MIDDELBEEK, NIELS JESSEN, PER G. OVESEN, MICHAEL F. HIRSHMAN, KRISTI B. ADAMO, EVA N. GRAYCK, LAURIE J. GOODYEAR

Diabetes 2020;69(Supplement_1):700-P

https://doi.org/10.2337/db20-700-P

Published: 01 June 2020

View article titled, 700-P: Mechanism for the Beneficial Effects of Maternal Exercise to Improve Offspring Metabolic Health

Meeting Abstracts

1887-P: Intermittent Hypoxia Increased the Expressions of Interleukin (IL)-8, Osteonectin, and Myonectin via OCT1 and Nrf2 Binding to the Promoters in Muscle Cells

SHIN TAKASAWA, RYOGO SHOBATAKE, ASAKO ITAYA-HIRONAKA, MAI MAKINO, SUMIYO SAKURAMOTO-TSUCHIDA, TOMOKO UCHIYAMA, HIROYO OTA, AKIYO YAMAUCHI

Diabetes 2020;69(Supplement_1):1887-P

https://doi.org/10.2337/db20-1887-P

Published: 01 June 2020

View article titled, 1887-P: Intermittent Hypoxia Increased the Expressions of Interleukin (IL)-8, Osteonectin, and Myonectin via OCT1 and Nrf2 Binding to the Promoters in Muscle Cells

Journal Articles

Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes

Liheng Wang, Qiongming Liu, Takumi Kitamoto, Junjie Hou, Jun Qin, Domenico Accili

Diabetes 2019;68(6):1156–1167

https://doi.org/10.2337/db18-1236

Published: 01 April 2019

View article titled, Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes

Includes: Supplementary data

Meeting Abstracts

Promoters of and Barriers to Engagement in Type 2 Diabetes Mellitus (T2DM) Populations with Real-World Technological Interventions

KEVIN R. DUVALL, ANJALI TRASY, ERIN MURRAY, ROBERT MILAM, TOBIAS SAYRE, ANNE C. BEAL

Diabetes 2018;67(Supplement_1):660-P

https://doi.org/10.2337/db18-660-P

Published: 01 July 2018

View article titled, Promoters of and Barriers to Engagement in Type 2 Diabetes Mellitus (T2DM) Populations with Real-World Technological Interventions

Journal Articles

Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

Zongzhe Jiang, Diwen Shi, Yifan Tu, Jingjing Tian, Wenjian Zhang, Bowen Xing, Jihua Wang, Suhuan Liu, Jinning Lou, Jan-Åke Gustafsson, Xianxin Hua, Xiaosong Ma

Diabetes 2018;67(7):1345–1355

https://doi.org/10.2337/db17-0885

Published: 01 May 2018

View article titled, Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

Includes: Supplementary data

Journal Articles

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution

Diabetes 2017;66(1):218–230

https://doi.org/10.2337/db16-0631

Published: 01 November 2016

View article titled, Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution

Includes: Supplementary data

Journal Articles

The Histone Acetylase Activator Pentadecylidenemalonate 1b Rescues Proliferation and Differentiation in the Human Cardiac Mesenchymal Cells of Type 2 Diabetic Patients

Diabetes 2014;63(6):2132–2147

https://doi.org/10.2337/db13-0731

Published: 15 May 2014

View article titled, The Histone Acetylase Activator Pentadecylidenemalonate 1b Rescues Proliferation and Differentiation in the Human Cardiac Mesenchymal Cells of Type 2 Diabetic Patients

Includes: Supplementary data

Journal Articles

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

Feng Miao, Zhuo Chen, Saul Genuth, Andrew Paterson, Lingxiao Zhang, Xiwei Wu, Sierra Min Li, Patricia Cleary, Arthur Riggs, David M. Harlan, Gayle Lorenzi, Orville Kolterman, Wanjie Sun, John M. Lachin, Rama Natarajan, the DCCT/EDIC Research Group

Diabetes 2014;63(5):1748–1762

https://doi.org/10.2337/db13-1251

Published: 12 April 2014

View article titled, Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

Louisa M. Villeneuve, Mitsuo Kato, Marpadga A. Reddy, Mei Wang, Linda Lanting, Rama Natarajan

Diabetes 2010;59(11):2904–2915

https://doi.org/10.2337/db10-0208

Published: 10 August 2010

View article titled, Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic <em>db/db</em> Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

Includes: Supplementary data

Journal Articles

Comparative Analysis of Insulin Gene Promoters : Implications for Diabetes Research

Colin W. Hay, Kevin Docherty

Diabetes 2006;55(12):3201–3213

https://doi.org/10.2337/db06-0788

Published: 01 December 2006

View article titled, Comparative Analysis of Insulin Gene Promoters : <subtitle>Implications for Diabetes Research</subtitle>

Journal Articles

Polymorphisms in Both Promoters of Hepatocyte Nuclear Factor 4-α Are Associated With Type 2 Diabetes in the Amish

Coleen M. Damcott, Nicole Hoppman, Sandra H. Ott, Laurie J. Reinhart, Jian Wang, Toni I. Pollin, Jeffrey R. O’Connell, Braxton D. Mitchell, Alan R. Shuldiner

Diabetes 2004;53(12):3337–3341

https://doi.org/10.2337/diabetes.53.12.3337

Published: 01 December 2004

View article titled, Polymorphisms in Both Promoters of Hepatocyte Nuclear Factor 4-α Are Associated With Type 2 Diabetes in the Amish

Journal Articles

Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ

Knut Tomas Dalen, Kristina Schoonjans, Stine M. Ulven, Mina Susanne Weedon-Fekjaer, Trine Gjesti Bentzen, Hana Koutnikova, Johan Auwerx, Hilde I. Nebb

Diabetes 2004;53(5):1243–1252

https://doi.org/10.2337/diabetes.53.5.1243

Published: 01 May 2004

View article titled, Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ

Includes: Supplementary data

Journal Articles

Inducible and Reversible β-Cell Autoimmunity and Hyperplasia in Transgenic Mice Expressing a Conditional Oncogene

Irina Berkovich, Shimon Efrat

Diabetes 2001;50(10):2260–2267

https://doi.org/10.2337/diabetes.50.10.2260

Published: 01 October 2001

View article titled, Inducible and Reversible β-Cell Autoimmunity and Hyperplasia in Transgenic Mice Expressing a Conditional Oncogene

Meeting Abstracts

Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.

J E Ayala, R S Streeper, J S Desgrosellier, S K Durham, A Suwanichkul, C A Svitek, J K Goldman, F G Barr, D R Powell, R M O'Brien

Diabetes 1999;48(9):1885–1889

https://doi.org/10.2337/diabetes.48.9.1885

Published: 01 September 1999

View article titled, Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.

Journal Articles

Cloning of the Promoters for the β-Cell ATP-Sensitive K-Channel Subunits Kir6.2 and SUR1

Rebecca Ashfield, Stephen J H Ashcroft

Diabetes 1998;47(8):1274–1280

https://doi.org/10.2337/diab.47.8.1274

Published: 01 August 1998

View article titled, Cloning of the Promoters for the β-Cell ATP-Sensitive K-Channel Subunits Kir6.2 and SUR1

Journal Articles

Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM

Christian Bjørbæk, Søren M Echwald, Peter Hubricht, Henrik Vestergaard, Torben Hansen, Juleen Zierath, Oluf Pedersen

Diabetes 1994;43(8):976–983

https://doi.org/10.2337/diab.43.8.976

Published: 01 August 1994

View article titled, Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM

NARROW

β-Cell–Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion

300-OR: A Modular Massively Parallel Reporter Assay Uncovers Context-Specific Activity of Diabetes-Associated Regulatory Elements

Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation

1199-P: The Oncogene MDM2 Induces M1 Macrophage Polarization and Adipose Tissue Inflammation in Obesity

700-P: Mechanism for the Beneficial Effects of Maternal Exercise to Improve Offspring Metabolic Health

1887-P: Intermittent Hypoxia Increased the Expressions of Interleukin (IL)-8, Osteonectin, and Myonectin via OCT1 and Nrf2 Binding to the Promoters in Muscle Cells

Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes

Promoters of and Barriers to Engagement in Type 2 Diabetes Mellitus (T2DM) Populations with Real-World Technological Interventions

Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution

The Histone Acetylase Activator Pentadecylidenemalonate 1b Rescues Proliferation and Differentiation in the Human Cardiac Mesenchymal Cells of Type 2 Diabetic Patients

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

Comparative Analysis of Insulin Gene Promoters : Implications for Diabetes Research

Polymorphisms in Both Promoters of Hepatocyte Nuclear Factor 4-α Are Associated With Type 2 Diabetes in the Amish

Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ

Inducible and Reversible β-Cell Autoimmunity and Hyperplasia in Transgenic Mice Expressing a Conditional Oncogene

Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.

Cloning of the Promoters for the β-Cell ATP-Sensitive K-Channel Subunits Kir6.2 and SUR1

Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM

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