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Meeting Abstracts

1569-P: Lysophosphatidic Acid Mediates Inflammation in Liver and White Adipose Tissue in a Rat Model of 1-acyl-sn-glycerol-3-phosphate Acyltransferase 2 Deficiency

IKKI SAKUMA, RAFAEL C. GASPAR, PANU LUUKKONEN, MARIO KAHN, SUE MURRAY, VARMAN SAMUEL, KITT PETERSEN, GERALD I. SHULMAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1569-P
https://doi.org/10.2337/db23-1569-P
Published: 20 June 2023
View article titled, 1569-P: Lysophosphatidic Acid Mediates Inflammation in Liver and White Adipose Tissue in a Rat Model of 1-acyl-sn-glycerol-3-phosphate Acyltransferase 2 Deficiency
Journal Articles

Metformin’s Therapeutic Efficacy in the Treatment of Diabetes Does Not Involve Inhibition of Mitochondrial Glycerol Phosphate Dehydrogenase

Michael J. MacDonald, Israr-ul H. Ansari, Melissa J. Longacre, Scott W. Stoker
Journal: Diabetes
Diabetes 2021;70(7):1575–1580
https://doi.org/10.2337/db20-1143
Published: 13 April 2021
View article titled, Metformin’s Therapeutic Efficacy in the Treatment of Diabetes Does Not Involve Inhibition of Mitochondrial Glycerol Phosphate Dehydrogenase
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Journal Articles

Lifting the Veil on the “Phosphate Flush,” a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology

Franz Matschinsky, David Wilson
Journal: Diabetes
Diabetes 2021;70(1):27–28
https://doi.org/10.2337/dbi20-0038
Published: 15 December 2020
View article titled, Lifting the Veil on the “Phosphate Flush,” a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology
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Journal Articles

XPR1 Mediates the Pancreatic β-Cell Phosphate Flush

Christopher J. Barker, Fernando Henrique Galvão Tessaro, Sabrina de Souza Ferreira, Rafael Simas, Thais S. Ayala, Martin Köhler, Subu Surendran Rajasekaran, Joilson O. Martins, Elisabetta Darè, Per-Olof Berggren
Journal: Diabetes
Diabetes 2021;70(1):111–118
https://doi.org/10.2337/db19-0633
Published: 21 August 2020
View article titled, XPR1 Mediates the Pancreatic β-Cell Phosphate Flush
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Meeting Abstracts

308-OR: Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Accelerates the Progression of Diabetic Glomerular Pathology

HUA QU, YI ZHENG
Journal: Diabetes
Diabetes 2020;69(Supplement_1):308-OR
https://doi.org/10.2337/db20-308-OR
Published: 01 June 2020
View article titled, 308-OR: Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Accelerates the Progression of Diabetic Glomerular Pathology
Meeting Abstracts

2031-P: Adipose-Specific Lack of Hexose-6-Phosphate Dehydrogenase Causes Inactivation of Adipose Glucocorticoids and Improves Metabolic Phenotype in Male Mice

JIAN WANG, XINXIANG WANG, KABIRULLAH LUTFY, THEODORE FRIEDMAN, MEISHENG JIANG, YANJUN LIU
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2031-P
https://doi.org/10.2337/db19-2031-P
Published: 01 June 2019
View article titled, 2031-P: Adipose-Specific Lack of Hexose-6-Phosphate Dehydrogenase Causes Inactivation of Adipose Glucocorticoids and Improves Metabolic Phenotype in Male Mice
Meeting Abstracts

Mitochondrial Glycerol 3-Phosphate Dehydrogenase Improves Skeletal Muscle Regeneration in Obesity and Diabetes

HUA QU, YI ZHENG
Journal: Diabetes
Diabetes 2018;67(Supplement_1):155-OR
https://doi.org/10.2337/db18-155-OR
Published: 01 July 2018
View article titled, Mitochondrial Glycerol 3-Phosphate Dehydrogenase Improves Skeletal Muscle Regeneration in Obesity and Diabetes
Meeting Abstracts

Identification of >150 Novel Exercise-Regulated Circulating Factors

LESLIE ROWLAND, ROELAND MIDDELBEEK, HUI PAN, JONATHAN DREYFUSS, LAURIE J. GOODYEAR
Journal: Diabetes
Diabetes 2018;67(Supplement_1):739-P
https://doi.org/10.2337/db18-739-P
Published: 01 July 2018
View article titled, Identification of >150 Novel Exercise-Regulated Circulating Factors
Journal Articles

Blunted Brain Energy Consumption Relates to Insula Atrophy and Impaired Glucose Tolerance in Obesity

Kamila Jauch-Chara, Ferdinand Binkofski, Michaela Loebig, Kathrin Reetz, Gianna Jahn, Uwe H. Melchert, Ulrich Schweiger, Kerstin M. Oltmanns
Journal: Diabetes
Diabetes 2015;64(6):2082–2091
https://doi.org/10.2337/db14-0421
Published: 09 January 2015
View article titled, Blunted Brain Energy Consumption Relates to Insula Atrophy and Impaired Glucose Tolerance in Obesity
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Includes: Supplementary data
Journal Articles

31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism

Douglas E. Befroy, Douglas L. Rothman, Kitt Falk Petersen, Gerald I. Shulman
Journal: Diabetes
Diabetes 2012;61(11):2669–2678
https://doi.org/10.2337/db12-0558
Published: 16 October 2012
View article titled, <sup>31</sup>P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism
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Journal Articles

Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

Catherine Arden, John L. Petrie, Susan J. Tudhope, Ziad Al-Oanzi, Amy J. Claydon, Robert J. Beynon, Howard C. Towle, Loranne Agius
Journal: Diabetes
Diabetes 2011;60(12):3110–3120
https://doi.org/10.2337/db11-0061
Published: 13 November 2011
View article titled, Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis
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Includes: Supplementary data
Journal Articles

Phosphatidylinositol-4-Phosphate-5-Kinase α Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice

Ping Huang, Oladapo Yeku, Haihong Zong, Phyllis Tsang, Wenjuan Su, Xiao Yu, Shuzhi Teng, Mary Osisami, Yasunori Kanaho, Jeffrey E. Pessin, Michael A. Frohman
Journal: Diabetes
Diabetes 2011;60(2):454–463
https://doi.org/10.2337/db10-0614
Published: 21 January 2011
View article titled, Phosphatidylinositol-4-Phosphate-5-Kinase α Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice
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Includes: Multimedia, Supplementary data
Journal Articles

Noninvasive Analysis of Hepatic Glycogen Kinetics Before and After Breakfast with Deuterated Water and Acetaminophen

John G. Jones, Ana Fagulha, Cristina Barosa, Margarida Bastos, Luisa Barros, Carla Baptista, M. Madalena Caldeira, Manuela Carvalheiro
Journal: Diabetes
Diabetes 2006;55(8):2294–2300
https://doi.org/10.2337/db06-0304
Published: 01 August 2006
View article titled, Noninvasive Analysis of Hepatic Glycogen Kinetics Before and After Breakfast with Deuterated Water and Acetaminophen
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Journal Articles

Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity

Chia-Wei Lin, Feifei Yan, Satoko Shimamura, Sebastian Barg, Show-Ling Shyng
Journal: Diabetes
Diabetes 2005;54(10):2852–2858
https://doi.org/10.2337/diabetes.54.10.2852
Published: 01 October 2005
View article titled, Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K<sup>+</sup> Channel Activity
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Journal Articles

Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic Islets and INS-1 Cells: Response to Cytokines

Lucy D. Mastrandrea, Shawn M. Sessanna, Suzanne G. Laychock
Journal: Diabetes
Diabetes 2005;54(5):1429–1436
https://doi.org/10.2337/diabetes.54.5.1429
Published: 01 May 2005
View article titled, Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic Islets and INS-1 Cells: <subtitle>Response to Cytokines</subtitle>
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Journal Articles

Scrutiny of the Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1) Locus Reveals Conserved Haplotype Block Structure not Associated With Diabetic Nephropathy

Daniel P.K. Ng, William H. Walker, Kee-Seng Chia, Serena Choo, James H. Warram, Andrzej S. Krolewski
Journal: Diabetes
Diabetes 2004;53(3):865–869
https://doi.org/10.2337/diabetes.53.3.865
Published: 01 March 2004
View article titled, Scrutiny of the Glutamine-Fructose-6-Phosphate Transaminase 1 (<em>GFPT1</em>) Locus Reveals Conserved Haplotype Block Structure not Associated With Diabetic Nephropathy
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Includes: Supplementary data
Journal Articles

Stimulation of Hepatocyte Glucose Metabolism by Novel Small Molecule Glucokinase Activators

Katy J. Brocklehurst, Victoria A. Payne, Rick A. Davies, Debra Carroll, Helen L. Vertigan, Heather J. Wightman, Susan Aiston, Ian D. Waddell, Brendan Leighton, Matthew P. Coghlan, Loranne Agius
Journal: Diabetes
Diabetes 2004;53(3):535–541
https://doi.org/10.2337/diabetes.53.3.535
Published: 01 March 2004
View article titled, Stimulation of Hepatocyte Glucose Metabolism by Novel Small Molecule Glucokinase Activators
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Journal Articles

A Mammalian Protein Homologous to Fructosamine-3-Kinase Is a Ketosamine-3-Kinase Acting on Psicosamines and Ribulosamines but not on Fructosamines

François Collard, Ghislain Delpierre, Vincent Stroobant, Gert Matthijs, Emile Van Schaftingen
Journal: Diabetes
Diabetes 2003;52(12):2888–2895
https://doi.org/10.2337/diabetes.52.12.2888
Published: 01 December 2003
View article titled, A Mammalian Protein Homologous to Fructosamine-3-Kinase Is a Ketosamine-3-Kinase Acting on Psicosamines and Ribulosamines but not on Fructosamines
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Journal Articles

Palmitate-Induced Activation of the Hexosamine Pathway in Human Myotubes: Increased Expression of Glutamine:Fructose-6-Phosphate Aminotransferase

Cora Weigert, Karsten Klopfer, Christiana Kausch, Katrin Brodbeck, Michael Stumvoll, Hans U. Häring, Erwin D. Schleicher
Journal: Diabetes
Diabetes 2003;52(3):650–656
https://doi.org/10.2337/diabetes.52.3.650
Published: 01 March 2003
View article titled, Palmitate-Induced Activation of the Hexosamine Pathway in Human Myotubes: <subtitle>Increased Expression of Glutamine:Fructose-6-Phosphate Aminotransferase </subtitle>
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Journal Articles

Glutaminolysis and Insulin Secretion: From Bedside to Bench and Back

Andrea Kelly, Changhong Li, Zhiyong Gao, Charles A. Stanley, Franz M. Matschinsky
Journal: Diabetes
Diabetes 2002;51(suppl_3):S421–S426
https://doi.org/10.2337/diabetes.51.2007.S421
Published: 01 December 2002
View article titled, Glutaminolysis and Insulin Secretion: <subtitle>From Bedside to Bench and Back </subtitle>
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