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Journal Articles

The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Carmella Evans-Molina

Diabetes 2024;73(4):545–553

https://doi.org/10.2337/dbi23-0030

Published: 20 March 2024

View article titled, The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Journal Articles

Daniel Porte Jr., 13 August 1931–13 May 2023

Steven E. Kahn, Stephen C. Woods, Jeffrey B. Halter, Gerald J. Taborsky, Michael W. Schwartz

Diabetes 2024;73(1):5–10

https://doi.org/10.2337/db23-0787

Published: 20 December 2023

View article titled, Daniel Porte Jr., 13 August 1931–13 May 2023

Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(9):1177–1178

https://doi.org/10.2337/db23-ti09

Published: 21 August 2023

View article titled, In This Issue of <em>Diabetes</em>

Journal Articles

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

Yi-Chun Chen, Austin J. Taylor, James M. Fulcher, Adam C. Swensen, Xiao-Qing Dai, Mitsuhiro Komba, Kenzie L.C. Wrightson, Kenny Fok, Annette E. Patterson, Ramon I. Klein Geltink, Patrick E. MacDonald, Wei-Jun Qian, C. Bruce Verchere

Diabetes 2023;72(9):1277–1288

https://doi.org/10.2337/db22-0945

Published: 26 June 2023

View article titled, Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

Meeting Abstracts

743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

TIMOTHY P. FOSTER, MICHAEL J. HALLER, DESMOND SCHATZ, CLIVE WASSERFALL, ELIAS SAYOUR

Diabetes 2023;72(Supplement_1):743-P

https://doi.org/10.2337/db23-743-P

Published: 20 June 2023

View article titled, 743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

Meeting Abstracts

1345-P: Proinsulin–to–C-Peptide Ratio Is Associated with the Time above the Target Glucose Range and the Duration of Type 2 Diabetes

AIKA MIYA, AKINOBU NAKAMURA, HIROSHI NOMOTO, HIRAKU KAMEDA, TATSUYA ATSUMI

Diabetes 2023;72(Supplement_1):1345-P

https://doi.org/10.2337/db23-1345-P

Published: 20 June 2023

View article titled, 1345-P: Proinsulin–to–C-Peptide Ratio Is Associated with the Time above the Target Glucose Range and the Duration of Type 2 Diabetes

Meeting Abstracts

1751-P: SERCA2 Regulates ER Lipid Composition and Proinsulin Processing

MARYALICE HARTLEY, MACKENZIE J. PEARSON, FAROOQ SYED, HAI BUI, TATSUYOSHI KONO, KENNETH D. ROTH, CARMELLA EVANS-MOLINA

Diabetes 2023;72(Supplement_1):1751-P

https://doi.org/10.2337/db23-1751-P

Published: 20 June 2023

View article titled, 1751-P: SERCA2 Regulates ER Lipid Composition and Proinsulin Processing

Journal Articles

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo

Rebecca K. Davidson, Sukrati Kanojia, Wenting Wu, Tatsuyoshi Kono, Jerry Xu, Meredith Osmulski, Robert N. Bone, Nolan Casey, Carmella Evans-Molina, Emily K. Sims, Jason M. Spaeth

Diabetes 2023;72(6):746–757

https://doi.org/10.2337/db22-0939

Published: 13 March 2023

View article titled, The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo

Journal Articles

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Mei-Ling Yang, Sean E. Connolly, Renelle J. Gee, TuKiet T. Lam, Jean Kanyo, Jian Peng, Perrin Guyer, Farooq Syed, Hubert M. Tse, Steven G. Clarke, Catherine F. Clarke, Eddie A. James, Cate Speake, Carmella Evans-Molina, Peter Arvan, Kevan C. Herold, Li Wen, Mark J. Mamula

Diabetes 2022;71(9):1979–1993

https://doi.org/10.2337/db21-0989

Published: 22 June 2022

View article titled, Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Meeting Abstracts

1302-P: Inhibitory Effect of Advanced Glycation End Products on Proinsulin Processing

SEBASTIAN BRINGS, WALTER MIER, BARBRO BEIJER, JULIA M. SZENDROEDI, PETER P. NAWROTH, THOMAS H. FLEMING

Diabetes 2022;71(Supplement_1):1302-P

https://doi.org/10.2337/db22-1302-P

Published: 01 June 2022

View article titled, 1302-P: Inhibitory Effect of Advanced Glycation End Products on Proinsulin Processing

Meeting Abstracts

1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

LAUREN A. FOWLER, VIBHU PARCHA, CATHARINE COUCH, W. TIMOTHY GARVEY, BARBARA GOWER

Diabetes 2022;71(Supplement_1):1118-P

https://doi.org/10.2337/db22-1118-P

Published: 01 June 2022

View article titled, 1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

Meeting Abstracts

361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D

TAMARA S. HANNON, SUSAN SAM, ASHLEY H. TJADEN, SHARON EDELSTEIN, KRISTEN J. NADEAU, SILVA A. ARSLANIAN, MELANIE CREE-GREEN, DAVID A. EHRMANN, KIEREN J. MATHER, STEVEN E. KAHN, THE RISE CONSORTIUM

Diabetes 2022;71(Supplement_1):361-OR

https://doi.org/10.2337/db22-361-OR

Published: 01 June 2022

View article titled, 361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D

Meeting Abstracts

1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

ANOOP ARUNAGIRI, MD MAROOF ALAM, LEENA HAATAJA, PRAVEEN J. SAMY, SCOTT SOLEIMANPOUR, LESLIE S. SATIN, PAMELA ITKIN-ANSARI, MING LIU, PETER ARVAN

Diabetes 2022;71(Supplement_1):1461-P

https://doi.org/10.2337/db22-1461-P

Published: 01 June 2022

View article titled, 1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

Meeting Abstracts

1456-P: Molecular Architecture of AR Action in Insulin Secretion in Male Pancreatic ß-Cells

PAULA MOTA DE SA, MIRZA MUHAMMAD FAHD QADIR, MANUEL BLANDINO-ROSANO, JIA FAN, WEIWEI XU, ERNESTO BERNAL-MIZRACHI, FRANCK MAUVAIS-JARVIS

Diabetes 2022;71(Supplement_1):1456-P

https://doi.org/10.2337/db22-1456-P

Published: 01 June 2022

View article titled, 1456-P: Molecular Architecture of AR Action in Insulin Secretion in Male Pancreatic ß-Cells

Journal Articles

Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580–2594

Maroof Alam, Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John Kappler, Niyun Jin, Peter Arvan

Diabetes 2022;71(4):870

https://doi.org/10.2337/db22-er04a

Published: 07 January 2022

View article titled, Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580–2594

Journal Articles

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Xiaoxi Xu, Yumeng Huang, Xin Li, Peter Arvan, Ming Liu

Diabetes 2022;71(3):440–452

https://doi.org/10.2337/db21-0638

Published: 02 December 2021

View article titled, The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Journal Articles

Diabetes: Concepts of β-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention

M. Arthur Charles, R. David Leslie

Diabetes 2021;70(11):2444–2456

https://doi.org/10.2337/dbi21-0012

Published: 22 October 2021

View article titled, Diabetes: Concepts of β-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention

Journal Articles

Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells

Rohit B. Sharma, Huguet V. Landa-Galván, Laura C. Alonso

Diabetes 2021;70(11):2431–2443

https://doi.org/10.2337/dbi20-0033

Published: 22 October 2021

View article titled, Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells

Journal Articles

Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus

Qing-Rong Liu, Min Zhu, Pingbo Zhang, Caio H. Mazucanti, Nicholas S. Huang, Doyle L. Lang, Qinghua Chen, Pavan Auluck, Stefano Marenco, Jennifer F. O’Connell, Luigi Ferrucci, Chee W. Chia, Josephine M. Egan

Diabetes 2021;70(12):2947–2956

https://doi.org/10.2337/db21-0198

Published: 14 October 2021

View article titled, Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus

Journal Articles

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

Maroof Alam, Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John Kappler, Niyun Jin, Peter Arvan

Diabetes 2021;70(11):2580–2594

https://doi.org/10.2337/db21-0422

Published: 30 August 2021

View article titled, Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

NARROW

The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Daniel Porte Jr., 13 August 1931–13 May 2023

In This Issue of Diabetes

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

1345-P: Proinsulin–to–C-Peptide Ratio Is Associated with the Time above the Target Glucose Range and the Duration of Type 2 Diabetes

1751-P: SERCA2 Regulates ER Lipid Composition and Proinsulin Processing

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

1302-P: Inhibitory Effect of Advanced Glycation End Products on Proinsulin Processing

1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D

1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

1456-P: Molecular Architecture of AR Action in Insulin Secretion in Male Pancreatic ß-Cells

Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580–2594

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Diabetes: Concepts of β-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention

Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells

Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

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