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Meeting Abstracts

16-OR: Protein Kinase C d Mediates Cytokine-Induced ß-Cell Death via Upregulation of Pro-apoptotic Signaling

JILLIAN COLLINS, NIKKI L. FARNSWORTH, RICHARD K. BENNINGER
Journal: Diabetes
Diabetes 2022;71(Supplement_1):16-OR
https://doi.org/10.2337/db22-16-OR
Published: 01 June 2022
View article titled, 16-OR: Protein Kinase C d Mediates Cytokine-Induced ß-Cell Death via Upregulation of Pro-apoptotic Signaling
Meeting Abstracts

289-OR: Cleavage of Protein Kinase C d by Caspase-3 Mediates Cytokine-Induced ß-Cell Death

JILLIAN COLLINS, RICHARD K. BENNINGER, NIKKI L. FARNSWORTH
Journal: Diabetes
Diabetes 2021;70(Supplement_1):289-OR
https://doi.org/10.2337/db21-289-OR
Published: 01 June 2021
View article titled, 289-OR: Cleavage of Protein Kinase C d by Caspase-3 Mediates Cytokine-Induced ß-Cell Death
Meeting Abstracts

720-P: Exercise Training Causes Vast Changes in the Circulating Factor Profile of Human Subjects

ROELAND MIDDELBEEK, JEFFREY J. RICHARD, LESLIE A. ROWLAND, PASQUALE NIGRO, HUI PAN, JONATHAN DREYFUSS, LAURIE J. GOODYEAR
Journal: Diabetes
Diabetes 2019;68(Supplement_1):720-P
https://doi.org/10.2337/db19-720-P
Published: 01 June 2019
View article titled, 720-P: Exercise Training Causes Vast Changes in the Circulating Factor Profile of Human Subjects
Meeting Abstracts

1787-P: Protein Kinase C (PKC) Negatively Regulate Neuronal Insulin Signaling In Vitro

DEVANSHI MISHRA, CHINMOY S. DEY
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1787-P
https://doi.org/10.2337/db19-1787-P
Published: 01 June 2019
View article titled, 1787-P: Protein Kinase C (PKC) Negatively Regulate Neuronal Insulin Signaling In Vitro
Journal Articles

Statement of Retraction. Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano, and Francesco Beguinot. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323

American Diabetes Association
Journal: Diabetes
Diabetes 2019;68(2):464–465
https://doi.org/10.2337/db19-rt02b
Published: 14 January 2019
View article titled, Statement of Retraction. Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano, and Francesco Beguinot. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323
Open the PDF for Statement of Retraction. Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano, and Francesco Beguinot. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323 in another window
Journal Articles

Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323

Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano, Francesco Beguinot
Journal: Diabetes
Diabetes 2018;67(2):345–346
https://doi.org/10.2337/db17-ec2017b
Published: 06 November 2017
View article titled, Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323
Open the PDF for Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50: 1244–1252 . DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323 in another window
Journal Articles

Hyperglycemia-Induced Protein Kinase C β2 Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling

Shaoqing Lei, Haobo Li, Jinjin Xu, Yanan Liu, Xia Gao, Junwen Wang, Kwok F.J. Ng, Wayne Bond Lau, Xin-liang Ma, Brian Rodrigues, Michael G. Irwin, Zhengyuan Xia
Journal: Diabetes
Diabetes 2013;62(7):2318–2328
https://doi.org/10.2337/db12-1391
Published: 14 June 2013
View article titled, Hyperglycemia-Induced Protein Kinase C β<sub>2</sub> Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling
Open the PDF for Hyperglycemia-Induced Protein Kinase C β<sub>2</sub> Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling in another window
Journal Articles

Hypothalamic Protein Kinase C Regulates Glucose Production

Rachel Ross, Penny Y.T. Wang, Madhu Chari, Carol K.L. Lam, Liora Caspi, Hiraku Ono, Evan D. Muse, Xiaosong Li, Roger Gutierrez-Juarez, Peter E. Light, Gary J. Schwartz, Luciano Rossetti, Tony K.T. Lam
Journal: Diabetes
Diabetes 2008;57(8):2061–2065
https://doi.org/10.2337/db08-0206
Published: 01 August 2008
View article titled, Hypothalamic Protein Kinase C Regulates Glucose Production
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Journal Articles

Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes

Carsten Schmitz-Peiffer, Trevor J. Biden
Journal: Diabetes
Diabetes 2008;57(7):1774–1783
https://doi.org/10.2337/db07-1769
Published: 01 July 2008
View article titled, Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes
Open the PDF for Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes in another window
Journal Articles

The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic

Farah S.L. Thong, Philip J. Bilan, Amira Klip
Journal: Diabetes
Diabetes 2007;56(2):414–423
https://doi.org/10.2337/db06-0900
Published: 01 February 2007
View article titled, The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic
Open the PDF for The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic in another window
Journal Articles

The Effect of Ruboxistaurin on Visual Loss in Patients With Moderately Severe to Very Severe Nonproliferative Diabetic Retinopathy : Initial Results of the Protein Kinase C β Inhibitor Diabetic Retinopathy Study (PKC-DRS) Multicenter Randomized Clinical Trial

The PKC-DRS Study Group
Journal: Diabetes
Diabetes 2005;54(7):2188–2197
https://doi.org/10.2337/diabetes.54.7.2188
Published: 01 July 2005
View article titled, The Effect of Ruboxistaurin on Visual Loss in Patients With Moderately Severe to Very Severe Nonproliferative Diabetic Retinopathy : <subtitle>Initial Results of the Protein Kinase C β Inhibitor Diabetic Retinopathy Study (PKC-DRS) Multicenter Randomized Clinical Trial</subtitle>
Open the PDF for The Effect of Ruboxistaurin on Visual Loss in Patients With Moderately Severe to Very Severe Nonproliferative Diabetic Retinopathy : <subtitle>Initial Results of the Protein Kinase C β Inhibitor Diabetic Retinopathy Study (PKC-DRS) Multicenter Randomized Clinical Trial</subtitle> in another window
Journal Articles

Effects of Polyol Pathway Hyperactivity on Protein Kinase C Activity, Nociceptive Peptide Expression, and Neuronal Structure in Dorsal Root Ganglia in Diabetic Mice

Kenji Uehara, Shin-Ichiro Yamagishi, Saori Otsuki, Shyunsuke Chin, Soroku Yagihashi
Journal: Diabetes
Diabetes 2004;53(12):3239–3247
https://doi.org/10.2337/diabetes.53.12.3239
Published: 01 December 2004
View article titled, Effects of Polyol Pathway Hyperactivity on Protein Kinase C Activity, Nociceptive Peptide Expression, and Neuronal Structure in Dorsal Root Ganglia in Diabetic Mice
Open the PDF for Effects of Polyol Pathway Hyperactivity on Protein Kinase C Activity, Nociceptive Peptide Expression, and Neuronal Structure in Dorsal Root Ganglia in Diabetic Mice in another window
Journal Articles

Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway

Vicki Thallas-Bonke, Carsten Lindschau, Bishoy Rizkalla, Leon A. Bach, Geoffrey Boner, Matthias Meier, Hermann Haller, Mark E. Cooper, Josephine M. Forbes
Journal: Diabetes
Diabetes 2004;53(11):2921–2930
https://doi.org/10.2337/diabetes.53.11.2921
Published: 01 November 2004
View article titled, Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway
Open the PDF for Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway in another window
Journal Articles

Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C

Benedek Erdös, James A. Snipes, Allison W. Miller, David W. Busija
Journal: Diabetes
Diabetes 2004;53(5):1352–1359
https://doi.org/10.2337/diabetes.53.5.1352
Published: 01 May 2004
View article titled, Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C
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Journal Articles

Exercise-Induced Protein Kinase C Isoform-Specific Activation in Human Skeletal Muscle

Sebastio Perrini, Jan Henriksson, Juleen R. Zierath, Ulrika Widegren
Journal: Diabetes
Diabetes 2004;53(1):21–24
https://doi.org/10.2337/diabetes.53.1.21
Published: 01 January 2004
View article titled, Exercise-Induced Protein Kinase C Isoform-Specific Activation in Human Skeletal Muscle
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Journal Articles

Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells : The Role of Protein Kinase C and NAD(P)H-Oxidase Activation

Lisa Quagliaro, Ludovica Piconi, Roberta Assaloni, Lucia Martinelli, Enrico Motz, Antonio Ceriello
Journal: Diabetes
Diabetes 2003;52(11):2795–2804
https://doi.org/10.2337/diabetes.52.11.2795
Published: 01 November 2003
View article titled, Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells : <subtitle>The Role of Protein Kinase C and NAD(P)H-Oxidase Activation</subtitle>
Open the PDF for Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells : <subtitle>The Role of Protein Kinase C and NAD(P)H-Oxidase Activation</subtitle> in another window
Journal Articles

Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction

Young-Bum Kim, Ko Kotani, Theodore P. Ciaraldi, Robert R. Henry, Barbara B. Kahn
Journal: Diabetes
Diabetes 2003;52(8):1935–1942
https://doi.org/10.2337/diabetes.52.8.1935
Published: 01 August 2003
View article titled, Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: <subtitle>Reversal With Weight Reduction</subtitle>
Open the PDF for Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: <subtitle>Reversal With Weight Reduction</subtitle> in another window
Journal Articles

Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells

Katrin Eitel, Harald Staiger, Johannes Rieger, Harald Mischak, Heide Brandhorst, Mathias D. Brendel, Reinhard G. Bretzel, Hans-Ulrich Häring, Monika Kellerer
Journal: Diabetes
Diabetes 2003;52(4):991–997
https://doi.org/10.2337/diabetes.52.4.991
Published: 01 April 2003
View article titled, Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells
Open the PDF for Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells in another window
Journal Articles

Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension

Darren J. Kelly, Yuan Zhang, Claire Hepper, Renae M. Gow, Kassie Jaworski, Bruce E. Kemp, Jennifer L. Wilkinson-Berka, Richard E. Gilbert
Journal: Diabetes
Diabetes 2003;52(2):512–518
https://doi.org/10.2337/diabetes.52.2.512
Published: 01 February 2003
View article titled, Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension
Open the PDF for Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension in another window
Journal Articles

Diacylglycerol Production and Protein Kinase C Activity Are Increased in a Mouse Model of Diabetic Embryopathy

Yuji Hiramatsu, Naotaka Sekiguchi, Michio Hayashi, Keiji Isshiki, Tamotsu Yokota, George L. King, Mary R. Loeken
Journal: Diabetes
Diabetes 2002;51(9):2804–2810
https://doi.org/10.2337/diabetes.51.9.2804
Published: 01 September 2002
View article titled, Diacylglycerol Production and Protein Kinase C Activity Are Increased in a Mouse Model of Diabetic Embryopathy
Open the PDF for Diacylglycerol Production and Protein Kinase C Activity Are Increased in a Mouse Model of Diabetic Embryopathy in another window