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Journal Articles

A three-week ketogenic diet increases skeletal muscle insulin sensitivity in individuals with obesity – a randomized, controlled crossover trial

Thien Vinh Luong, MD, PhD, Mette Glavind Bülow Pedersen, MD, PhD, Caroline Bruun Abild, RD, Katrine Meyer Lauritsen, MD, PhD, Mette Louise Gram Kjærulff, MD, Niels Møller, MD,DMSc, Lars Christian Gormsen, MD, PhD, Esben Søndergaard, MD, PhD
Journal: Diabetes
Diabetes db240162
https://doi.org/10.2337/db24-0162
Published: 25 July 2024
View article titled, A three-week ketogenic diet increases skeletal muscle insulin sensitivity in individuals with obesity – a randomized, controlled crossover trial
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Journal Articles

Interrelationships Among Accumulations of Intra- and Periorgan Fats, Visceral Fat, and Subcutaneous Fat

Kento Mitsushio, Megu Y. Baden, Takuya Kagisaki, Sarasa Kato, Akiko Niki, Risa Takayama, Tomomi Horii, Harutoshi Ozawa, Chisaki Ishibashi, Yoshiya Hosokawa, Yukari Fujita, Junji Kozawa, Iichiro Shimomura
Journal: Diabetes
Diabetes 2024;73(7):1122–1126
https://doi.org/10.2337/db24-0035
Published: 24 April 2024
View article titled, Interrelationships Among Accumulations of Intra- and Periorgan Fats, Visceral Fat, and Subcutaneous Fat
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Journal Articles

Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance

Soyoung Park, Hye-Na Cha, Min-Gyeong Shin, Sanghee Park, Yeongmin Kim, Min-Seob Kim, Kyung-Hoon Shin, Themis Thoudam, Eun Ju Lee, Robert R. Wolfe, Jinmyoung Dan, Jin-Ho Koh, Il-Young Kim, Inho Choi, In-Kyu Lee, Hoon-Ki Sung, So-Young Park
Journal: Diabetes
Diabetes 2024;73(7):1084–1098
https://doi.org/10.2337/db23-0432
Published: 24 April 2024
View article titled, Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance
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Journal Articles

Pharmacological Activation of PDC Flux Reverses Lipid-Induced Inhibition of Insulin Action in Muscle During Recovery From Exercise

Christian S. Carl, Marie M. Jensen, Kim A. Sjøberg, Dumitru Constantin-Teodosiu, Ian R. Hill, Rasmus Kjøbsted, Paul L. Greenhaff, Jørgen F.P. Wojtaszewski, Erik A. Richter, Andreas M. Fritzen, Bente Kiens
Journal: Diabetes
Diabetes 2024;73(7):1072–1083
https://doi.org/10.2337/db23-0879
Published: 12 April 2024
View article titled, Pharmacological Activation of PDC Flux Reverses Lipid-Induced Inhibition of Insulin Action in Muscle During Recovery From Exercise
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Journal Articles

Depletion of TBC1D4 Improves the Metabolic Exercise Response by Overcoming Genetically Induced Peripheral Insulin Resistance

Christian Springer, Christian Binsch, Deborah Weide, Laura Toska, Anna L. Cremer, Heiko Backes, Anna K. Scheel, Lena Espelage, Jörg Kotzka, Sebastian Sill, Anette Kurowski, Daebin Kim, Sandra Karpinski, Theresia M. Schnurr, Torben Hansen, Sonja Hartwig, Stefan Lehr, Sandra Cames, Jens C. Brüning, Matthias Lienhard, Ralf Herwig, Stefan Börno, Bernd Timmermann, Hadi Al-Hasani, Alexandra Chadt
Journal: Diabetes
Diabetes 2024;73(7):1058–1071
https://doi.org/10.2337/db23-0463
Published: 12 April 2024
View article titled, Depletion of TBC1D4 Improves the Metabolic Exercise Response by Overcoming Genetically Induced Peripheral Insulin Resistance
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Journal Articles

Comment on Pataky et al. Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors. Diabetes 2024;73:23–37

Adam Astrada
Journal: Diabetes
Diabetes 2024;73(6):e3
https://doi.org/10.2337/db24-0033
Published: 09 April 2024
View article titled, Comment on Pataky et al. Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors. Diabetes 2024;73:23–37
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Journal Articles

Response to Comment on Pataky et al. Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors. Diabetes 2024;73:23–37

Mark W. Pataky, K. Sreekumaran Nair
Journal: Diabetes
Diabetes 2024;73(6):e4–e5
https://doi.org/10.2337/dbi24-0017
Published: 20 March 2024
View article titled, Response to Comment on Pataky et al. Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors. Diabetes 2024;73:23–37
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Journal Articles

Molecular Insights From Multiomics Studies of Physical Activity

Wei Wei, Steffen H. Raun, Jonathan Z. Long
Journal: Diabetes
Diabetes 2024;73(2):162–168
https://doi.org/10.2337/dbi23-0004
Published: 19 January 2024
View article titled, Molecular Insights From Multiomics Studies of Physical Activity
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Journal Articles

Paper of the Month 2023 Winners

Journal: Diabetes
Diabetes 2024;73(1):3–4
https://doi.org/10.2337/db24-en01
Published: 20 December 2023
View article titled, Paper of the Month 2023 Winners
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Journal Articles

Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors

Mark W. Pataky, Arathi Prabha Kumar, David A. Gaul, Samuel G. Moore, Surendra Dasari, Matthew M. Robinson, Katherine A. Klaus, A. Aneesh Kumar, Facundo M. Fernandez, K. Sreekumaran Nair
Journal: Diabetes
Diabetes 2024;73(1):23–37
https://doi.org/10.2337/db23-0142
Published: 20 October 2023
View article titled, Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors
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Journal Articles

A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques

Keenan T. Greyslak, Byron Hetrick, Bryan C. Bergman, Tyler A. Dean, Stephanie R. Wesolowski, Maureen Gannon, Simon Schenk, Elinor L. Sullivan, Kjersti M. Aagaard, Paul Kievit, Adam J. Chicco, Jacob E. Friedman, Carrie E. McCurdy
Journal: Diabetes
Diabetes 2023;72(12):1766–1780
https://doi.org/10.2337/db23-0289
Published: 19 September 2023
View article titled, A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques
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Journal Articles

AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores

Kohei Kido, Nicolas O. Eskesen, Nicolai S. Henriksen, Johan Onslev, Jonas M. Kristensen, Magnus R. Larsen, Janne R. Hingst, Jonas R. Knudsen, Jesper B. Birk, Nicoline R. Andersen, Thomas E. Jensen, Christian Pehmøller, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted
Journal: Diabetes
Diabetes 2023;72(10):1397–1408
https://doi.org/10.2337/db23-0358
Published: 28 July 2023
View article titled, AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores
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Meeting Abstracts

1636-P: The Effects of MS-275 Derivative in Diabetic Skeletal Muscle Atrophy

NAMI LEE, YUJIN KIM, SUJI CHOI, YOUNGHA KIM, YOUNGHO SON, SUNGE CHOI, YUP Y. KANG, JA YOUNG JEON, SEUNG JIN HAN, HAE JIN KIM, TAE HO KIM, SOYEON AN, KWANWOO LEE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1636-P
https://doi.org/10.2337/db23-1636-P
Published: 20 June 2023
View article titled, 1636-P: The Effects of MS-275 Derivative in Diabetic Skeletal Muscle Atrophy
Meeting Abstracts

838-P: Reversion of Nonalcoholic Steatohepatitis by Skeletal-Muscle Directed FGF21 Gene Therapy

VERONICA JIMENEZ, VÍCTOR SACRISTÁN, CLAUDIA JAMBRINA, MARIA LUISA JAÉN, SERGIO A. MUNOZ, ESTEFANIA CASANA, MIQUEL GARCIA, IGNASI GRASS, XAVIER LEON, IVET ELIAS, ALBERT RIBERA, GEMMA ELIAS, VICTOR SANCHEZ, ALBA CASELLAS, TURA FERRÉ, MARIA MOLAS, FATIMA BOSCH
Journal: Diabetes
Diabetes 2023;72(Supplement_1):838-P
https://doi.org/10.2337/db23-838-P
Published: 20 June 2023
View article titled, 838-P: Reversion of Nonalcoholic Steatohepatitis by Skeletal-Muscle Directed FGF21 Gene Therapy
Meeting Abstracts

33-OR: Epigenetic Reader BRD4 Directs Fast-Twitch Myofiber Gene Programs Influencing Skeletal Muscle Endurance Capacity and Systemic Glucose Homeostasis

ZHENG ZHOU, LIN LIU, ZHISHENG XU, TINGTING FU, LIKUN YANG, MAO YAN, ZHENJI GAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):33-OR
https://doi.org/10.2337/db23-33-OR
Published: 20 June 2023
View article titled, 33-OR: Epigenetic Reader BRD4 Directs Fast-Twitch Myofiber Gene Programs Influencing Skeletal Muscle Endurance Capacity and Systemic Glucose Homeostasis
Meeting Abstracts

265-LB: Human Skeletal Muscle Mitochondrial Dynamics across the Insulin-Sensitivity Spectrum

CHRISTOPHER L. AXELROD, WAGNER S. DANTAS, ELIZABETH R.M. ZUNICA, KATHRYN BELMONT, ELIZABETH C. HEINTZ, GANGARAO DAVULURI, JACOB T. MEY, MELISSA ERICKSON, HISASHI FUJIOKA, CIARAN FEALY, CHARLES L. HOPPEL, JOHN P. KIRWAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):265-LB
https://doi.org/10.2337/db23-265-LB
Published: 20 June 2023
View article titled, 265-LB: Human Skeletal Muscle Mitochondrial Dynamics across the Insulin-Sensitivity Spectrum
Meeting Abstracts

264-LB: Aerobic Exercise Training Reorganizes Skeletal Muscle Mitochondrial and Lipid Droplet Architecture

HAILEY A. PARRY, CHRISTOPHER L. AXELROD, VALENTINA BAENA, WAGNER S. DANTAS, JOHN P. KIRWAN, BRIAN GLANCY
Journal: Diabetes
Diabetes 2023;72(Supplement_1):264-LB
https://doi.org/10.2337/db23-264-LB
Published: 20 June 2023
View article titled, 264-LB: Aerobic Exercise Training Reorganizes Skeletal Muscle Mitochondrial and Lipid Droplet Architecture
Meeting Abstracts

305-OR: Short-Term Hyperglycemia Impacts Mouse Skeletal Muscle in a Sex-Specific Manner

NICHOLAS A. HULETT, LESLIE KNAUB, GREGORY POTT, DAVID RAMIREZ, ASPEN JOHNSTON, REBECCA L. SCALZO, JANE E.B. REUSCH
Journal: Diabetes
Diabetes 2023;72(Supplement_1):305-OR
https://doi.org/10.2337/db23-305-OR
Published: 20 June 2023
View article titled, 305-OR: Short-Term Hyperglycemia Impacts Mouse Skeletal Muscle in a Sex-Specific Manner
Meeting Abstracts

587-P: AS160 Expression, but Not AS160 Serine-588, Threonine-642, and Serine-704 Phosphorylation, Is Essential for Elevated Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female Rats after Acute Exercise

HAIYAN WANG, AMY ZHENG, EDWARD B. ARIAS, SEONGEUN KWAK, XIUFANG PAN, YONGPING YUE, DONGSHENG DUAN, GREGORY D. CARTEE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):587-P
https://doi.org/10.2337/db23-587-P
Published: 20 June 2023
View article titled, 587-P: AS160 Expression, but Not AS160 Serine-588, Threonine-642, and Serine-704 Phosphorylation, Is Essential for Elevated Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female Rats after Acute Exercise
Meeting Abstracts

1644-P: Exercise and Caloric Restriction Exert Different Benefits on Metabolism and Mechanical Function of Skeletal Muscle in Aging Condition

CHANISA THONUSIN, PATCHARAPONG PANTIYA, WICHWARA NAWARA, BUSARIN ARUNSAK, SIRAWIT SRIWICHAIIN, NIPON CHATTIPAKORN, SIRIPORN C. CHATTIPAKORN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1644-P
https://doi.org/10.2337/db23-1644-P
Published: 20 June 2023
View article titled, 1644-P: Exercise and Caloric Restriction Exert Different Benefits on Metabolism and Mechanical Function of Skeletal Muscle in Aging Condition