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Meeting Abstracts

1807-PUB: Monocarbonyl Curcumin Analogs C66 and B2BrBC Improve Redox Status in Streptozotocin-Induced Diabetic Rats

RADOSLAV STOJCHEVSKI, MARIJA ANGELOVSKI, SARA VELICHKOVIKJ, NIKOLA HADZI-PETRUSHEV, JANE B. BOGDANOV, MITKO MLADENOV, LEONID PORETSKY, DIMITER AVTANSKI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1807-PUB
https://doi.org/10.2337/db23-1807-PUB
Published: 23 June 2023
View article titled, 1807-PUB: Monocarbonyl Curcumin Analogs C66 and B2BrBC Improve Redox Status in Streptozotocin-Induced Diabetic Rats
Meeting Abstracts

1549-P: scEMC10 Promotes Glucose Intolerance via the Inhibition of PKA-Mediated Insulin Secretion

JIARONG DAI, SHAN LIU, KUANGYANG CHEN, SHUOSHUO JIN, YAHAO WANG, LIJIAO CHEN, XUANCHUN WANG
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1549-P
https://doi.org/10.2337/db23-1549-P
Published: 20 June 2023
View article titled, 1549-P: scEMC10 Promotes Glucose Intolerance via the Inhibition of PKA-Mediated Insulin Secretion
Journal Articles

Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos
Journal: Diabetes
Diabetes 2023;72(5):638–652
https://doi.org/10.2337/db22-0515
Published: 23 February 2023
View article titled, Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy
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Journal Articles

Neutrophil Extracellular Traps Induce Glomerular Endothelial Cell Dysfunction and Pyroptosis in Diabetic Kidney Disease

Fengfan Zheng, Linqiang Ma, Xuan Li, Zhihong Wang, Rufei Gao, Chuan Peng, Bing Kang, Yue Wang, Ting Luo, Jinshan Wu, Yi Yang, Lilin Gong, Qifu Li, Shumin Yang, Jinbo Hu
Journal: Diabetes
Diabetes 2022;71(12):2739–2750
https://doi.org/10.2337/db22-0153
Published: 12 September 2022
View article titled, Neutrophil Extracellular Traps Induce Glomerular Endothelial Cell Dysfunction and Pyroptosis in Diabetic Kidney Disease
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Journal Articles

Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF

Yuki Nakafusa, Naoyoshi Nitta, Kazunari Ishii, Naoto Shirasu, Takahiro Iwamoto, Takayuki Nemoto, Masafumi Nakamura, Masafumi Goto, Hiroo Iwata, Masaru Taniguchi, Yohichi Yasunami
Journal: Diabetes
Diabetes 2022;71(8):1721–1734
https://doi.org/10.2337/db21-0684
Published: 21 August 2022
View article titled, Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF
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Journal Articles

REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice

Siddharth Sunilkumar, Esma I. Yerlikaya, Allyson L. Toro, William P. Miller, Han Chen, Kebin Hu, Scot R. Kimball, Michael D. Dennis
Journal: Diabetes
Diabetes 2022;71(11):2412–2425
https://doi.org/10.2337/db22-0402
Published: 19 August 2022
View article titled, REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice
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Meeting Abstracts

1351-P: Molecular Pathogenesis of NASH through the Dysregulation of Metabolic Organ Network in the NASH-HCC Model Mouse Treated with Streptozotocin, High-Fat Diet

LINH P. BUI, YUKI SAKAKIBARA, RYUTO TANAKA, ELIZABETH H. PIGNEY, TAISHI HASHIGUCHI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1351-P
https://doi.org/10.2337/db22-1351-P
Published: 01 June 2022
View article titled, 1351-P: Molecular Pathogenesis of NASH through the Dysregulation of Metabolic Organ Network in the NASH-HCC Model Mouse Treated with Streptozotocin, High-Fat Diet
Meeting Abstracts

557-P: Effect of Monocarbonyl Curcumin Analogues C66 and B2BrBC on Pancreatic Expression of Genes Related to Insulin Signaling Pathway and Oxidative Stress in Streptozotocin-Induced Diabetes

RADOSLAV STOJCHEVSKI, MARIJA ANGELOVSKI, SARA VELICHKOVIKJ, NIKOLA HADZI-PETRUSHEV, MITKO MLADENOV, JANE B. BOGDANOV, LEONID PORETSKY, DIMITER AVTANSKI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):557-P
https://doi.org/10.2337/db22-557-P
Published: 01 June 2022
View article titled, 557-P: Effect of Monocarbonyl Curcumin Analogues C66 and B2BrBC on Pancreatic Expression of Genes Related to Insulin Signaling Pathway and Oxidative Stress in Streptozotocin-Induced Diabetes
Meeting Abstracts

15-OR: Mitochondrial NRF2 in ß-cell Oxidative Stress Response

ALISSA NOVAK, JUSTIN CROWDER, MICHELLE MARASCO, AMELIA K. LINNEMANN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):15-OR
https://doi.org/10.2337/db22-15-OR
Published: 01 June 2022
View article titled, 15-OR: Mitochondrial NRF2 in ß-cell Oxidative Stress Response
Meeting Abstracts

1444-P: Knockdown of Etv5 Impairs Viability of Pancreatic Beta Cells by Enhancing ROS Production

XUANZI YI, FAHIMEH BAGHNAVI, CEDRIC DIEKMANN, GÜNTER PÄTH, JOCHEN SEUFERT
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1444-P
https://doi.org/10.2337/db22-1444-P
Published: 01 June 2022
View article titled, 1444-P: Knockdown of Etv5 Impairs Viability of Pancreatic Beta Cells by Enhancing ROS Production
Journal Articles

Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice

William P. Miller, Allyson L. Toro, Siddharth Sunilkumar, Shaunaci A. Stevens, Ashley M. VanCleave, David L. Williamson, Alistair J. Barber, Michael D. Dennis
Journal: Diabetes
Diabetes 2022;71(5):1051–1062
https://doi.org/10.2337/db21-0853
Published: 15 February 2022
View article titled, Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice
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Journal Articles

Canagliflozin Prevents Hyperglycemia-Associated Muscle Extracellular Matrix Accumulation and Improves the Adaptive Response to Aerobic Exercise

Tara L. MacDonald, Pattarawan Pattamaprapanont, Eileen M. Cooney, Roberto C. Nava, Joanna Mitri, Samar Hafida, Sarah J. Lessard
Journal: Diabetes
Diabetes 2022;71(5):881–893
https://doi.org/10.2337/db21-0934
Published: 02 February 2022
View article titled, Canagliflozin Prevents Hyperglycemia-Associated Muscle Extracellular Matrix Accumulation and Improves the Adaptive Response to Aerobic Exercise
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Journal Articles

GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression

Vanessa Königs, Sandra Pierre, Martin Schicht, Jessica Welss, Lisa Hahnefeld, Vittoria Rimola, Elke Lütjen-Drecoll, Gerd Geisslinger, Klaus Scholich
Journal: Diabetes
Diabetes 2022;71(4):774–787
https://doi.org/10.2337/db21-0711
Published: 21 January 2022
View article titled, GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression
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Journal Articles

Heal Thyself: SGLT2 Inhibition Limits Regenerative Cell Exhaustion and Heals Damaged Vessels

David A. Hess, Daniella C. Terenzi, Subodh Verma
Journal: Diabetes
Diabetes 2021;70(8):1620–1622
https://doi.org/10.2337/dbi21-0025
Published: 13 August 2021
View article titled, Heal Thyself: SGLT2 Inhibition Limits Regenerative Cell Exhaustion and Heals Damaged Vessels
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Journal Articles

Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes

Dasan Mary Cibi, Reddemma Sandireddy, Hanumakumar Bogireddi, Nicole Tee, Siti Aishah Binte Abdul Ghani, Brijesh K. Singh, Nigel Mackman, Manvendra K. Singh, Anamika Singh
Journal: Diabetes
Diabetes 2021;70(9):2131–2146
https://doi.org/10.2337/db20-0719
Published: 21 June 2021
View article titled, Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes
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Journal Articles

Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease

Tatsuhiko Azegami, Takashin Nakayama, Kaori Hayashi, Akihito Hishikawa, Norifumi Yoshimoto, Ran Nakamichi, Hiroshi Itoh
Journal: Diabetes
Diabetes 2021;70(9):2147–2158
https://doi.org/10.2337/db20-1257
Published: 21 June 2021
View article titled, Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease
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Journal Articles

The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism Through the AMPK/PPARα/CPT1b Pathway

Liang Wu, Changjie Liu, Dong-Yuan Chang, Rui Zhan, Mingming Zhao, Sin Man Lam, Guanghou Shui, Ming-Hui Zhao, Lemin Zheng, Min Chen
Journal: Diabetes
Diabetes 2021;70(10):2192–2203
https://doi.org/10.2337/db21-0050
Published: 08 June 2021
View article titled, The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism Through the AMPK/PPARα/CPT1b Pathway
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Meeting Abstracts

209-LB: RNA-Seq Analysis of Liver from Diabetic and NASH Model Mouse Treated with Streptozotocin, High-Fat Diet

LINH P. BUI, YUKI SAKAKIBARA, RYUTO TANAKA, ELIZABETH H. PIGNEY, TAISHI HASHIGUCHI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):209-LB
https://doi.org/10.2337/db21-209-LB
Published: 01 June 2021
View article titled, 209-LB: RNA-Seq Analysis of Liver from Diabetic and NASH Model Mouse Treated with Streptozotocin, High-Fat Diet
Meeting Abstracts

433-P: Hyperglycemia-Induced Oxidative Stress Prevents REDD1 Degradation by Chaperone-Mediated Autophagy

WILLIAM P. MILLER, ALLYSON TORO, SIDDHARTH SUNILKUMAR, JOSEPH GIORDANO, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):433-P
https://doi.org/10.2337/db21-433-P
Published: 01 June 2021
View article titled, 433-P: Hyperglycemia-Induced Oxidative Stress Prevents REDD1 Degradation by Chaperone-Mediated Autophagy
Journal Articles

Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy

Priyamvada M. Pitale, Irina V. Saltykova, Yvonne Adu-Agyeiwaah, Sergio Li Calzi, Takashi Satoh, Shizuo Akira, Oleg Gorbatyuk, Michael E. Boulton, Machelle T. Pardue, W. Timothy Garvey, Mohammad Athar, Maria B. Grant, Marina S. Gorbatyuk
Journal: Diabetes
Diabetes 2021;70(8):1738–1753
https://doi.org/10.2337/db20-1268
Published: 11 May 2021
View article titled, Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy
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