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Meeting Abstracts

1722-P: RIPK1 Promotes Thapsigargin-Induced ß-Cell Death Independent of Caspase 3/7 Activity In Vitro

NOYONIKA MUKHERJEE, CHRISTOPHER J. CONTRERAS, LI LIN, ERICA P. CAI, ANDREW T. TEMPLIN

Diabetes 2023;72(Supplement_1):1722-P

https://doi.org/10.2337/db23-1722-P

Published: 20 June 2023

View article titled, 1722-P: RIPK1 Promotes Thapsigargin-Induced ß-Cell Death Independent of Caspase 3/7 Activity In Vitro

Journal Articles

Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Jinghe Li, Ryota Inoue, Yu Togashi, Tomoko Okuyama, Aoi Satoh, Mayu Kyohara, Kuniyuki Nishiyama, Takahiro Tsuno, Daisuke Miyashita, Tatsuya Kin, A.M. James Shapiro, Resilind Su Ern Chew, Adrian Kee Keong Teo, Seiichi Oyadomari, Yasuo Terauchi, Jun Shirakawa

Diabetes 2022;71(3):424–439

https://doi.org/10.2337/db21-0123

Published: 29 September 2021

View article titled, Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Meeting Abstracts

2130-P: Imeglimin Modulated ER Stress to Prevent ß-Cell Apoptosis Induced by High Glucose or Thapsigargin

JINGHE LI, JUN SHIRAKAWA, YU TOGASHI, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):2130-P

https://doi.org/10.2337/db19-2130-P

Published: 01 June 2019

View article titled, 2130-P: Imeglimin Modulated ER Stress to Prevent ß-Cell Apoptosis Induced by High Glucose or Thapsigargin

Journal Articles

Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function

Arianne Aslamy, Eunjin Oh, Erika M. Olson, Jing Zhang, Miwon Ahn, Abu Saleh Md Moin, Ragadeepthi Tunduguru, Vishal A. Salunkhe, Rajakrishnan Veluthakal, Debbie C. Thurmond

Diabetes 2018;67(7):1332–1344

https://doi.org/10.2337/db17-1352

Published: 16 April 2018

View article titled, Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function

Includes: Supplementary data

Journal Articles

Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells

Paul V. Sabatini, Nicole A.J. Krentz, Bader Zarrouki, Clara Y. Westwell-Roper, Cuilan Nian, Ryan A. Uy, A.M. James Shapiro, Vincent Poitout, Francis C. Lynn

Diabetes 2013;62(8):2808–2820

https://doi.org/10.2337/db12-1527

Published: 17 July 2013

View article titled, Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Wendy M. McKimpson, Jeremy Weinberger, Lech Czerski, Min Zheng, Michael T. Crow, Jeffrey E. Pessin, Streamson C. Chua, Jr., Richard N. Kitsis

Diabetes 2013;62(1):183–193

https://doi.org/10.2337/db12-0504

Published: 13 December 2012

View article titled, The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Includes: Supplementary data

Journal Articles

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Junqin Chen, Ghislaine Fontes, Geetu Saxena, Vincent Poitout, Anath Shalev

Diabetes 2010;59(2):440–447

https://doi.org/10.2337/db09-0949

Published: 29 October 2009

View article titled, Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Includes: Supplementary data

Journal Articles

Roles of IP₃R and RyR Ca²⁺ Channels in Endoplasmic Reticulum Stress and β-Cell Death

Dan S. Luciani, Kamila S. Gwiazda, Ting-Lin B. Yang, Tatyana B. Kalynyak, Yaryna Bychkivska, Matthew H.Z. Frey, Kristin D. Jeffrey, Arthur V. Sampaio, T. Michael Underhill, James D. Johnson

Diabetes 2009;58(2):422–432

https://doi.org/10.2337/db07-1762

Published: 01 February 2009

View article titled, Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and β-Cell Death

Journal Articles

Inositol (1,4,5)-Trisphosphate Dynamics and Intracellular Calcium Oscillations in Pancreatic β-Cells

Natalia A. Tamarina, Andrey Kuznetsov, Christopher J. Rhodes, Vytautas P. Bindokas, Louis H. Philipson

Diabetes 2005;54(11):3073–3081

https://doi.org/10.2337/diabetes.54.11.3073

Published: 01 November 2005

View article titled, Inositol (1,4,5)-Trisphosphate Dynamics and Intracellular Calcium Oscillations in Pancreatic β-Cells

Journal Articles

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca²⁺ ATPase 2b and Deplete Endoplasmic Reticulum Ca²⁺, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Alessandra K. Cardozo, Fernanda Ortis, Joachim Storling, Ying-Mei Feng, Joanne Rasschaert, Morten Tonnesen, Françoise Van Eylen, Thomas Mandrup-Poulsen, André Herchuelz, Décio L. Eizirik

Diabetes 2005;54(2):452–461

https://doi.org/10.2337/diabetes.54.2.452

Published: 01 February 2005

View article titled, Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Journal Articles

Hyperglycemia Inhibits Capacitative Calcium Entry and Hypertrophy in Neonatal Cardiomyocytes

Yi Pang, Dacia L. Hunton, Pam Bounelis, Richard B. Marchase

Diabetes 2002;51(12):3461–3467

https://doi.org/10.2337/diabetes.51.12.3461

Published: 01 December 2002

View article titled, Hyperglycemia Inhibits Capacitative Calcium Entry and Hypertrophy in Neonatal Cardiomyocytes

Journal Articles

Na/Ca Exchanger Overexpression Induces Endoplasmic Reticulum–Related Apoptosis and Caspase-12 Activation in Insulin-Releasing BRIN-BD11 Cells

Oscar Diaz-Horta, Adama Kamagate, André Herchuelz, Françoise Van Eylen

Diabetes 2002;51(6):1815–1824

https://doi.org/10.2337/diabetes.51.6.1815

Published: 01 June 2002

View article titled, Na/Ca Exchanger Overexpression Induces Endoplasmic Reticulum–Related Apoptosis and Caspase-12 Activation in Insulin-Releasing BRIN-BD11 Cells

Journal Articles

Dynamic Imaging of Endoplasmic Reticulum Ca²⁺ Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: Roles of Sarco(endo)plasmic Reticulum Ca²⁺-ATPase (SERCA)-2 and Ryanodine Receptors

Aniko Varadi, Guy A. Rutter

Diabetes 2002;51(suppl_1):S190–S201

https://doi.org/10.2337/diabetes.51.2007.S190

Published: 01 February 2002

View article titled, Dynamic Imaging of Endoplasmic Reticulum Ca2+ Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: <subtitle>Roles of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2 and Ryanodine Receptors </subtitle>

Journal Articles

RX871024 Induces Ca²⁺ Mobilization From Thapsigargin-Sensitive Stores in Mouse Pancreatic β-Cells

Ioulia B Efanova, Sergei V Zaitsev, Graham Brown, Per-Olof Berggren, Suad Efendić

Diabetes 1998;47(2):211–218

https://doi.org/10.2337/diab.47.2.211

Published: 01 February 1998

View article titled, RX871024 Induces Ca2+ Mobilization From Thapsigargin-Sensitive Stores in Mouse Pancreatic β-Cells

NARROW

1722-P: RIPK1 Promotes Thapsigargin-Induced ß-Cell Death Independent of Caspase 3/7 Activity In Vitro

Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

2130-P: Imeglimin Modulated ER Stress to Prevent ß-Cell Apoptosis Induced by High Glucose or Thapsigargin

Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function

Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Roles of IP₃R and RyR Ca²⁺ Channels in Endoplasmic Reticulum Stress and β-Cell Death

Inositol (1,4,5)-Trisphosphate Dynamics and Intracellular Calcium Oscillations in Pancreatic β-Cells

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca²⁺ ATPase 2b and Deplete Endoplasmic Reticulum Ca²⁺, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Hyperglycemia Inhibits Capacitative Calcium Entry and Hypertrophy in Neonatal Cardiomyocytes

Na/Ca Exchanger Overexpression Induces Endoplasmic Reticulum–Related Apoptosis and Caspase-12 Activation in Insulin-Releasing BRIN-BD11 Cells

Dynamic Imaging of Endoplasmic Reticulum Ca²⁺ Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: Roles of Sarco(endo)plasmic Reticulum Ca²⁺-ATPase (SERCA)-2 and Ryanodine Receptors

RX871024 Induces Ca²⁺ Mobilization From Thapsigargin-Sensitive Stores in Mouse Pancreatic β-Cells

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