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Journal Articles

Role of Sec61α2 Translocon in Insulin Biosynthesis

Xiaoxi Xu, Thomas W. Bell, Truc Le, Ivy Zhao, Emily Walker, Yiqing Wang, Ning Xu, Scott A. Soleimanpour, Holger A. Russ, Ling Qi, Billy Tsai, Ming Liu, Peter Arvan
Journal: Diabetes
Diabetes 2024;73(12):2034–2044
https://doi.org/10.2337/db24-0115
Published: 26 September 2024
View article titled, Role of Sec61α2 Translocon in Insulin Biosynthesis
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Meeting Abstracts

193-OR: Muscle α-Parvin Deletion Results in Insulin Resistance by Impairing GLUT4 Translocation and Hexokinase II Association with Mitochondria in Mice

DAVID A. CAPPEL, JOHN W. DEAVER, LUCIANO COZZANI, DEANNA BRACY, LOUISE LANTIER, XINYU DONG, RICHARD PRINTZ, ROY ZENT, AMBRA POZZI, DAVID H. WASSERMAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):193-OR
https://doi.org/10.2337/db23-193-OR
Published: 20 June 2023
View article titled, 193-OR: Muscle α-Parvin Deletion Results in Insulin Resistance by Impairing GLUT4 Translocation and Hexokinase II Association with Mitochondria in Mice
Meeting Abstracts

1417-P: Gut Microbiome Translocation to Visceral Adipose Tissue Promotes Recruitment of Adipose-Specific Neutrophils in Human Obesity

DHARTI SHANTARAM, ALECIA M. BLASZCZAK, REBECCA HOYD, ALAN SMITH, LINDA ANTWI, JOEY Z. LIU, VALERIE P. WRIGHT, DAVID BRADLEY, YUNZHOU LIU, NYELIA F. WILLIAMS, DAN SPAKOWICZ, WILLA HSUEH
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1417-P
https://doi.org/10.2337/db22-1417-P
Published: 01 June 2022
View article titled, 1417-P: Gut Microbiome Translocation to Visceral Adipose Tissue Promotes Recruitment of Adipose-Specific Neutrophils in Human Obesity
Journal Articles

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Xiaoxi Xu, Yumeng Huang, Xin Li, Peter Arvan, Ming Liu
Journal: Diabetes
Diabetes 2022;71(3):440–452
https://doi.org/10.2337/db21-0638
Published: 02 December 2021
View article titled, The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum
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Meeting Abstracts

335-OR: Lipid-Induced Insulin Resistance in the Renal Cortex Is Associated with Plasma Membrane Sn-1,2-diacylglycerol Accumulation and PKCe Translocation

BRANDON T. HUBBARD, RAFAEL C. GASPAR, DONGYAN ZHANG, MARIO KAHN, ALI NASIRI, XIAN-MAN ZHANG, GARY CLINE, GERALD I. SHULMAN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):335-OR
https://doi.org/10.2337/db21-335-OR
Published: 01 June 2021
View article titled, 335-OR: Lipid-Induced Insulin Resistance in the Renal Cortex Is Associated with Plasma Membrane Sn-1,2-diacylglycerol Accumulation and PKCe Translocation
Meeting Abstracts

108-OR: Inhibition of SerpinB13 Stimulates Beta-Cell Development via Notch Signaling Pathway

YURY KRYVALAP, COLE HENDRICKSON, JAN CZYZYK
Journal: Diabetes
Diabetes 2019;68(Supplement_1):108-OR
https://doi.org/10.2337/db19-108-OR
Published: 01 June 2019
View article titled, 108-OR: Inhibition of SerpinB13 Stimulates Beta-Cell Development via Notch Signaling Pathway
Meeting Abstracts

197-OR: IL-6 Protects Pancreatic ß Cells from Oxidative Stress via NRF2 Mitochondrial Translocation and Mitophagy

MICHELLE MARASCO, ABASS M. CONTEH, CHARANYA MURALIDHARAN, ELIZABETH PFEIFER, AMELIA K. LINNEMANN
Journal: Diabetes
Diabetes 2019;68(Supplement_1):197-OR
https://doi.org/10.2337/db19-197-OR
Published: 01 June 2019
View article titled, 197-OR: IL-6 Protects Pancreatic ß Cells from Oxidative Stress via NRF2 Mitochondrial Translocation and Mitophagy
Meeting Abstracts

Angiotensin-Converting Enzyme 2 Deficiency Increases Translocation of Gut Bacteria by Depletion of Bone Marrow-Derived Circulating Angiogenic Cells

YAQIAN DUAN, DONGNI FENG, ELENI BELI, SERGIO LI CALZI, ANA LEDA F. LONGHINI, REGINA LAMENDELLA, JUSTIN R. WRIGHT, TROY A. MARKEL, ALEXANDER G. OBUKHOV, MARIA B. GRANT
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1899-P
https://doi.org/10.2337/db18-1899-P
Published: 01 July 2018
View article titled, Angiotensin-Converting Enzyme 2 Deficiency Increases Translocation of Gut Bacteria by Depletion of Bone Marrow-Derived Circulating Angiogenic Cells
Journal Articles

Rab8a Deficiency in Skeletal Muscle Causes Hyperlipidemia and Hepatosteatosis by Impairing Muscle Lipid Uptake and Storage

Qiaoli Chen, Ping Rong, Dijin Xu, Sangsang Zhu, Liang Chen, Bingxian Xie, Qian Du, Chao Quan, Yang Sheng, Tong-Jin Zhao, Peng Li, Hong Yu Wang, Shuai Chen
Journal: Diabetes
Diabetes 2017;66(9):2387–2399
https://doi.org/10.2337/db17-0077
Published: 10 July 2017
View article titled, Rab8a Deficiency in Skeletal Muscle Causes Hyperlipidemia and Hepatosteatosis by Impairing Muscle Lipid Uptake and Storage
Open the PDF for Rab8a Deficiency in Skeletal Muscle Causes Hyperlipidemia and Hepatosteatosis by Impairing Muscle Lipid Uptake and Storage in another window
Includes: Supplementary data
Journal Articles

Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Ida Alenkvist, Nikhil R. Gandasi, Sebastian Barg, Anders Tengholm
Journal: Diabetes
Diabetes 2017;66(10):2610–2622
https://doi.org/10.2337/db17-0050
Published: 05 July 2017
View article titled, Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis
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Journal Articles

Exercise Ameliorates Insulin Resistance via Ca2+ Signals Distinct From Those of Insulin for GLUT4 Translocation in Skeletal Muscles

Dae-Ryoung Park, Kwang-Hyun Park, Byung-Ju Kim, Chung-Su Yoon, Uh-Hyun Kim
Journal: Diabetes
Diabetes 2015;64(4):1224–1234
https://doi.org/10.2337/db14-0939
Published: 19 November 2014
View article titled, Exercise Ameliorates Insulin Resistance via Ca<sup>2+</sup> Signals Distinct From Those of Insulin for GLUT4 Translocation in Skeletal Muscles
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Includes: Supplementary data
Journal Articles

Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

Dieter Rondas, Inne Crèvecoeur, Wannes D’Hertog, Gabriela Bomfim Ferreira, An Staes, Abhishek D. Garg, Decio L. Eizirik, Patrizia Agostinis, Kris Gevaert, Lut Overbergh, Chantal Mathieu
Journal: Diabetes
Diabetes 2015;64(2):573–586
https://doi.org/10.2337/db14-0621
Published: 09 September 2014
View article titled, Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

PRMT3 Regulates Hepatic Lipogenesis Through Direct Interaction With LXRα

Dong-il Kim, Min-jung Park, Seul-ki Lim, Jae-il Park, Kyung-chul Yoon, Ho-jae Han, Jan-Åke Gustafsson, Jae-hyang Lim, Soo-hyun Park
Journal: Diabetes
Diabetes 2015;64(1):60–71
https://doi.org/10.2337/db13-1394
Published: 03 September 2014
View article titled, PRMT3 Regulates Hepatic Lipogenesis Through Direct Interaction With LXRα
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Includes: Supplementary data
Journal Articles

Exercise Training Induces Mitochondrial Biogenesis and Glucose Uptake in Subcutaneous Adipose Tissue Through eNOS-Dependent Mechanisms

Elisabetta Trevellin, Michele Scorzeto, Massimiliano Olivieri, Marnie Granzotto, Alessandra Valerio, Laura Tedesco, Roberto Fabris, Roberto Serra, Marco Quarta, Carlo Reggiani, Enzo Nisoli, Roberto Vettor
Journal: Diabetes
Diabetes 2014;63(8):2800–2811
https://doi.org/10.2337/db13-1234
Published: 17 July 2014
View article titled, Exercise Training Induces Mitochondrial Biogenesis and Glucose Uptake in Subcutaneous Adipose Tissue Through eNOS-Dependent Mechanisms
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Journal Articles

B-Cell Translocation Gene 2 Regulates Hepatic Glucose Homeostasis via Induction of Orphan Nuclear Receptor Nur77 in Diabetic Mouse Model

Yong Deuk Kim, Sun-Gyun Kim, Seung-Lark Hwang, Hueng-Sik Choi, Jae-Hoon Bae, Dae-Kyu Song, Seung-Soon Im
Journal: Diabetes
Diabetes 2014;63(6):1870–1880
https://doi.org/10.2337/db13-1368
Published: 15 May 2014
View article titled, B-Cell Translocation Gene 2 Regulates Hepatic Glucose Homeostasis via Induction of Orphan Nuclear Receptor Nur77 in Diabetic Mouse Model
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Journal Articles

Putting Rac1 on the Path to Glucose Uptake

Assaf Rudich, Amira Klip
Journal: Diabetes
Diabetes 2013;62(6):1831–1832
https://doi.org/10.2337/db13-0381
Published: 17 May 2013
View article titled, Putting Rac1 on the Path to Glucose Uptake
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Journal Articles

Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kγ-Akt-AS160 in Skeletal Muscle Cells

Cesar Osorio-Fuentealba, Ariel E. Contreras-Ferrat, Francisco Altamirano, Alejandra Espinosa, Qing Li, Wenyan Niu, Sergio Lavandero, Amira Klip, Enrique Jaimovich
Journal: Diabetes
Diabetes 2013;62(5):1519–1526
https://doi.org/10.2337/db12-1066
Published: 16 April 2013
View article titled, Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kγ-Akt-AS160 in Skeletal Muscle Cells
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Includes: Supplementary data
Journal Articles

Blocking the Entrance to Open the Gate

Patrick Schrauwen, Silvie Timmers, Matthijs K.C. Hesselink
Journal: Diabetes
Diabetes 2013;62(3):703–705
https://doi.org/10.2337/db12-1663
Published: 14 February 2013
View article titled, Blocking the Entrance to Open the Gate
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Journal Articles

Doc2b Is a Key Effector of Insulin Secretion and Skeletal Muscle Insulin Sensitivity

Latha Ramalingam, Eunjin Oh, Stephanie M. Yoder, Joseph T. Brozinick, Michael A. Kalwat, Alexander J. Groffen, Matthijs Verhage, Debbie C. Thurmond
Journal: Diabetes
Diabetes 2012;61(10):2424–2432
https://doi.org/10.2337/db11-1525
Published: 13 September 2012
View article titled, Doc2b Is a Key Effector of Insulin Secretion and Skeletal Muscle Insulin Sensitivity
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Includes: Supplementary data
Journal Articles

Brain GLP-1 Signaling Regulates Femoral Artery Blood Flow and Insulin Sensitivity Through Hypothalamic PKC-δ

Cendrine Cabou, Christelle Vachoux, Gérard Campistron, Daniel J. Drucker, Rémy Burcelin
Journal: Diabetes
Diabetes 2011;60(9):2245–2256
https://doi.org/10.2337/db11-0464
Published: 20 August 2011
View article titled, Brain GLP-1 Signaling Regulates Femoral Artery Blood Flow and Insulin Sensitivity Through Hypothalamic PKC-δ
Open the PDF for Brain GLP-1 Signaling Regulates Femoral Artery Blood Flow and Insulin Sensitivity Through Hypothalamic PKC-δ in another window
Includes: Supplementary data