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Meeting Abstracts

183-OR: Overcoming Immunological Barriers for “Off-the-Shelf” iPSC-Derived Islets

XIAOMENG HU, KATHY WHITE, ARI G. OLROYD, ROWENA DEJESUS, ANTONIA DOMINGUEZ, WILLIAM E. DOWDLE, ELAINE Y.L. CHU, ANNABELLE FRIERA, CHI YOUNG, FRANK WELLS, TREVOR MCGILL, MICHAEL RUKSTALIS, CORIE GATTIS, RONALD BASCO, JEFFREY R. MILLMAN, SONJA SCHREPFER

Diabetes 2022;71(Supplement_1):183-OR

DOI: https://doi.org/10.2337/db22-183-OR

Published: 01 June 2022

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Meeting Abstracts

304-OR: Proteomic Profile and Inflammatory Response of Islet Stressomes Released during Isolation

PRATHAB BALAJI SARAVANAN, JAGAN KALIVARATHAN, MARLON F. LEVY, MAZHAR A. KANAK

Diabetes 2022;71(Supplement_1):304-OR

DOI: https://doi.org/10.2337/db22-304-OR

Published: 01 June 2022

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Journal Articles

Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

Braxton L. Jamison, James E. DiLisio, K. Scott Beard, Tobias Neef, Brenda Bradley, Jessica Goodman, Ronald G. Gill, Stephen D. Miller, Rocky L. Baker, Kathryn Haskins

Diabetes 2022;71(3):483–496

DOI: https://doi.org/10.2337/db20-1170

Published: 18 January 2022

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Meeting Abstracts

1144-P: Chemical Assessment of Populations of Human Pancreatic Islets Isolated for Transplantation

STANISLAV RUBAKHIN, ELENA V. ROMANOVA, JONATHAN V. SWEEDLER

Diabetes 2021;70(Supplement_1):1144-P

DOI: https://doi.org/10.2337/db21-1144-P

Published: 01 June 2021

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Journal Articles

Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research

Mollie S.H. Friedlander, Vy M. Nguyen, Seung K. Kim, Romina J. Bevacqua

Diabetes 2021;70(5):1051–1060

DOI: https://doi.org/10.2337/db20-1115

Published: 19 May 2021

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Journal Articles

Building Biomimetic Potency Tests for Islet Transplantation

Aaron L. Glieberman, Benjamin D. Pope, Douglas A. Melton, Kevin Kit Parker

Diabetes 2021;70(2):347–363

DOI: https://doi.org/10.2337/db20-0297

Published: 14 January 2021

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Journal Articles

Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

Xin Tong, Chunhua Dai, John T. Walker, Gopika G. Nair, Arion Kennedy, Rotonya M. Carr, Matthias Hebrok, Alvin C. Powers, Roland Stein

Diabetes 2020;69(3):342–354

DOI: https://doi.org/10.2337/db19-0281

Published: 13 December 2020

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Includes: Supplementary data

Journal Articles

InsB9-23 Gene Transfer to Hepatocyte-Based Combined Therapy Abrogates Recurrence of Type 1 Diabetes After Islet Transplantation

Fabio Russo, Antonio Citro, Giorgia Squeri, Francesca Sanvito, Paolo Monti, Silvia Gregori, Maria Grazia Roncarolo, Andrea Annoni

Diabetes 2021;70(1):171–181

DOI: https://doi.org/10.2337/db19-1249

Published: 29 October 2020

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Journal Articles

Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

Jessie M. Barra, Veronika Kozlovskaya, Eugenia Kharlampieva, Hubert M. Tse

Diabetes 2020;69(9):1948–1960

DOI: https://doi.org/10.2337/db20-0248

Published: 25 June 2020

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Meeting Abstracts

1683-P: Upregulation of Pancreatic Islet EGF Receptor Improves Beta-Cell Identity and In Vivo Vascularisation in a Directly Observed Transplant Model

VICTORIA SALEM, USAMA ALI, KINGA SUBA, STAVROULA BITSI, TATIANA LOPES, ALDARA MARTIN ALONSO, YATEEN S. PATEL, ISABELLE LECLERC, BRYN OWEN, GUY A. RUTTER, STEPHEN M. ROTHERY, ALEJANDRA TOMAS

Diabetes 2020;69(Supplement_1):1683-P

DOI: https://doi.org/10.2337/db20-1683-P

Published: 01 June 2020

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Meeting Abstracts

1689-P: Perioperative Hyperglycemia around Renal Transplantation Surgery and the Development of New-Onset Diabetes Mellitus after Transplantation

MARÍA LETICIA MÉNDEZ FERREIRA, ELVIO D. BUENO, ALDO BENITEZ, CONCEPCION M. PALACIOS, JORGE T. JIMENEZ, ALEJANDRA AMARILLA, FERNANDO DA PONTE, IDALINA STANLEY

Diabetes 2020;69(Supplement_1):1689-P

DOI: https://doi.org/10.2337/db20-1689-P

Published: 01 June 2020

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Meeting Abstracts

361-OR: BETA-2 Score Is Highly Predictive of Graft Function after Islet Transplant: Analysis of Clinical Islet Transplant Consortium Trials

PETER A. SENIOR, MICHAEL R. RICKELS, THOMAS EGGERMAN, LEVENT BAYMAN, JULIE QIDWAI, RODOLFO ALEJANDRO, JAMES F. MARKMANN, LAWRENCE G. HUNSICKER, CLINICAL ISLET TRANSPLANT CONSORTIUM

Diabetes 2020;69(Supplement_1):361-OR

DOI: https://doi.org/10.2337/db20-361-OR

Published: 01 June 2020

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Meeting Abstracts

358-OR: ß-Cell Function and Insulin Sensitivity with Islet Alone and Islet-after-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation (CIT) Consortium

MICHAEL R. RICKELS, THOMAS EGGERMAN, LEVENT BAYMAN, JULIE QIDWAI, JOSEPH NAJI, HUONG-LAN T. NGUYEN, RODOLFO ALEJANDRO, MELENA BELLIN, PETER SENIOR, LAWRENCE G. HUNSICKER, CLINICAL ISLET TRANSPLANTATION CONSORTIUM

Diabetes 2020;69(Supplement_1):358-OR

DOI: https://doi.org/10.2337/db20-358-OR

Published: 01 June 2020

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Meeting Abstracts

115-OR: Early Insulin Pump Use in Pediatric Post–Total Pancreatectomy Islet Auto Transplantation Management

SIOBHAN E. TELLEZ, LINDSEY HORNUNG, JOSHUA D. COURTER, MAISAM ABU-EL-HAIJA, JAIMIE D. NATHAN, SARAH LAWSON, DEBORAH A. ELDER

Diabetes 2020;69(Supplement_1):115-OR

DOI: https://doi.org/10.2337/db20-115-OR

Published: 01 June 2020

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Meeting Abstracts

471-P: Transplantation of Apoptosis Resistant Endothelial Progenitor Cells (EPC) May Improve Renal Function in Both Type 1 and 2 Diabetic Kidney Disease (DKD)

NABANITA KUNDU, LAUREANO D. ASICO, PEDRO A. JOSE, SABYASACHI SEN

Diabetes 2020;69(Supplement_1):471-P

DOI: https://doi.org/10.2337/db20-471-P

Published: 01 June 2020

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Meeting Abstracts

257-OR: Profiling Transcriptional Maturation of Human Pluripotent Stem Cell–Derived Islets after Transplantation

PUNN AUGSORNWORAWAT, KRISTINA G. MAXWELL, JEFFREY R. MILLMAN

Diabetes 2020;69(Supplement_1):257-OR

DOI: https://doi.org/10.2337/db20-257-OR

Published: 01 June 2020

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Meeting Abstracts

2067-P: Cell Therapies for Diabetes Using Spontaneous Canine Diabetes as a Translational Model

ALDYN WILDEY, SUSAN J. WILLIAMS, MEGAN HAMILTON, STEPHEN HARRINGTON, LINDSEY OTT, FRANCIS KARANU

Diabetes 2020;69(Supplement_1):2067-P

DOI: https://doi.org/10.2337/db20-2067-P

Published: 01 June 2020

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Meeting Abstracts

205-LB: Clinical Validation of the Implanted Prevascularized Cell Pouch as a Viable, Safe Site for Diabetes Cell Therapy

AMANDA S. MACGILLIVARY, PHILIP M. TOLEIKIS, DELFINA M. MAZZUCA

Diabetes 2020;69(Supplement_1):205-LB

DOI: https://doi.org/10.2337/db20-205-LB

Published: 01 June 2020

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Meeting Abstracts

549-P: Transplantation of Human Dental Pulp Stem Cells Ameliorates Diabetic Polyneuropathy via Increasing Angiogenic and Neurotrophic Gene Expression in the Transplanted Muscles

MASAKI HATA, MAIKO OMI, NOBUHISA NAKAMURA, MEGUMI MIYABE, MIZUHO ITO, ERIKO MAKINO, SAKI KANADA, TASUKU ONO, YUKA IMANISHI, TATSUHITO HIMENO, JIRO NAKAMURA, HIDEKI KAMIYA, SHOGO OZAWA, JUN TAKEBE, TATSUAKI MATSUBARA, KEIKO NARUSE

Diabetes 2020;69(Supplement_1):549-P

DOI: https://doi.org/10.2337/db20-549-P

Published: 01 June 2020

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Journal Articles

Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

Diabetes 2020;69(8):1779–1792

DOI: https://doi.org/10.2337/db19-0829

Published: 13 May 2020

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2 3 4 5

NARROW

183-OR: Overcoming Immunological Barriers for “Off-the-Shelf” iPSC-Derived Islets

304-OR: Proteomic Profile and Inflammatory Response of Islet Stressomes Released during Isolation

Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

1144-P: Chemical Assessment of Populations of Human Pancreatic Islets Isolated for Transplantation

Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research

Building Biomimetic Potency Tests for Islet Transplantation

Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

InsB9-23 Gene Transfer to Hepatocyte-Based Combined Therapy Abrogates Recurrence of Type 1 Diabetes After Islet Transplantation

Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

1683-P: Upregulation of Pancreatic Islet EGF Receptor Improves Beta-Cell Identity and In Vivo Vascularisation in a Directly Observed Transplant Model

1689-P: Perioperative Hyperglycemia around Renal Transplantation Surgery and the Development of New-Onset Diabetes Mellitus after Transplantation

361-OR: BETA-2 Score Is Highly Predictive of Graft Function after Islet Transplant: Analysis of Clinical Islet Transplant Consortium Trials

358-OR: ß-Cell Function and Insulin Sensitivity with Islet Alone and Islet-after-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation (CIT) Consortium

115-OR: Early Insulin Pump Use in Pediatric Post–Total Pancreatectomy Islet Auto Transplantation Management

471-P: Transplantation of Apoptosis Resistant Endothelial Progenitor Cells (EPC) May Improve Renal Function in Both Type 1 and 2 Diabetic Kidney Disease (DKD)

257-OR: Profiling Transcriptional Maturation of Human Pluripotent Stem Cell–Derived Islets after Transplantation

2067-P: Cell Therapies for Diabetes Using Spontaneous Canine Diabetes as a Translational Model

205-LB: Clinical Validation of the Implanted Prevascularized Cell Pouch as a Viable, Safe Site for Diabetes Cell Therapy

549-P: Transplantation of Human Dental Pulp Stem Cells Ameliorates Diabetic Polyneuropathy via Increasing Angiogenic and Neurotrophic Gene Expression in the Transplanted Muscles

Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

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