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Meeting Abstracts

2289-PUB: Comparison of GalT-KO Porcine Islet Xenograft Survival between Microcapsule against Hypoxia and Microcapsule against Fibrosis in Diabetic Mice Model

EUN YOUNG LEE, YEOREE YANG, YUNJUNG CHO, SEUNG-HWAN LEE, JAE-HYOUNG CHO, KUN-HO YOON

Diabetes 2020;69(Supplement_1):2289-PUB

DOI: https://doi.org/10.2337/db20-2289-PUB

Published: 01 June 2020

View article titled, 2289-PUB: Comparison of GalT-KO Porcine Islet Xenograft Survival between Microcapsule against Hypoxia and Microcapsule against Fibrosis in Diabetic Mice Model

Meeting Abstracts

263-OR: IgM Therapy Reverses Autoimmune Diabetes and Prevents Islet Allo- and Xenotransplant Rejection

MINGYANG MA, KENNETH L. BRAYMAN, PREETI CHHABRA

Diabetes 2019;68(Supplement_1):263-OR

DOI: https://doi.org/10.2337/db19-263-OR

Published: 01 June 2019

View article titled, 263-OR: IgM Therapy Reverses Autoimmune Diabetes and Prevents Islet Allo- and Xenotransplant Rejection

Journal Articles

Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Qifa Ye, Pengpeng Zhang, Qiquan Wan

Diabetes 2016;65(2):e8

DOI: https://doi.org/10.2337/db15-1201

Published: 13 January 2016

View article titled, Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Journal Articles

Erratum. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61: 1180–1191

Shounan Yi, Ming Ji, Jingjing Wu, Xiaoqian Ma, Peta Phillips, Wayne J. Hawthorne, Philip J. O’Connell

Diabetes 2016;65(2):534

DOI: https://doi.org/10.2337/db16-er02

Published: 13 January 2016

View article titled, Erratum. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61: 1180–1191

Journal Articles

Response to Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Philip John O'Connell, Shounan Yi

Diabetes 2016;65(2):e9–e10

DOI: https://doi.org/10.2337/dbi15-0042

Published: 13 January 2016

View article titled, Response to Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Journal Articles

Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts

Shusen Wang, James Tasch, Taba Kheradmand, Jodie Ulaszek, Sora Ely, Xiaomin Zhang, Bernhard J. Hering, Stephen D. Miller, Xunrong Luo

Diabetes 2013;62(9):3143–3150

DOI: https://doi.org/10.2337/db12-1678

Published: 15 August 2013

View article titled, Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts

Includes: Supplementary data

Journal Articles

Clinical Islet Xenotransplantation: How Close Are We?

Dirk J. van der Windt, Rita Bottino, Goutham Kumar, Martin Wijkstrom, Hidetaka Hara, Mohamed Ezzelarab, Burcin Ekser, Carol Phelps, Noriko Murase, Anna Casu, David Ayares, Fadi G. Lakkis, Massimo Trucco, David K.C. Cooper

Diabetes 2012;61(12):3046–3055

DOI: https://doi.org/10.2337/db12-0033

Published: 15 November 2012

View article titled, Clinical Islet Xenotransplantation: <span class="subtitle">How Close Are We?</span>

Journal Articles

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

Shounan Yi, Ming Ji, Jingjing Wu, Xiaoqian Ma, Peta Phillips, Wayne J. Hawthorne, Philip J. O’Connell

Diabetes 2012;61(5):1180–1191

DOI: https://doi.org/10.2337/db11-1306

Published: 13 April 2012

View article titled, Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

Includes: Supplementary data

Journal Articles

Short-Term Administrations of a Combination of Anti–LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

Hossein Arefanian, Eric B. Tredget, Ray V. Rajotte, Ron G. Gill, Gregory S. Korbutt, Gina R. Rayat

Diabetes 2010;59(4):958–966

DOI: https://doi.org/10.2337/db09-0413

Published: 19 January 2010

View article titled, Short-Term Administrations of a Combination of Anti–LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

Journal Articles

Achieving Permanent Survival of Islet Xenografts by Independent Manipulation of Direct and Indirect T-Cell Responses

Vincenzo Mirenda, Dela Golshayan, Joseph Read, Ivan Berton, Anthony N. Warrens, Anthony Dorling, Robert I. Lechler

Diabetes 2005;54(4):1048–1055

DOI: https://doi.org/10.2337/diabetes.54.4.1048

Published: 01 April 2005

View article titled, Achieving Permanent Survival of Islet Xenografts by Independent Manipulation of Direct and Indirect T-Cell Responses

Journal Articles

Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB

Gina R. Rayat, Ronald G. Gill

Diabetes 2005;54(2):443–451

DOI: https://doi.org/10.2337/diabetes.54.2.443

Published: 01 February 2005

View article titled, Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB

Journal Articles

Autoimmune Diabetes and Resistance to Xenograft Transplantation Tolerance in NOD Mice

Ethel J. Gordon, Linda S. Wicker, Laurence B. Peterson, David V. Serreze, Thomas G. Markees, Leonard D. Shultz, Aldo A. Rossini, Dale L. Greiner, John P. Mordes

Diabetes 2005;54(1):107–115

DOI: https://doi.org/10.2337/diabetes.54.1.107

Published: 01 January 2005

View article titled, Autoimmune Diabetes and Resistance to Xenograft Transplantation Tolerance in NOD Mice

Journal Articles

The Degree of Phylogenetic Disparity of Islet Grafts Dictates the Reliance on Indirect CD4 T-Cell Antigen Recognition for Rejection

Gina R. Rayat, Zachary A. Johnson, Joshua N. Beilke, Gregory S. Korbutt, Ray V. Rajotte, Ronald G. Gill

Diabetes 2003;52(6):1433–1440

DOI: https://doi.org/10.2337/diabetes.52.6.1433

Published: 01 June 2003

View article titled, The Degree of Phylogenetic Disparity of Islet Grafts Dictates the Reliance on Indirect CD4 T-Cell Antigen Recognition for Rejection

Journal Articles

A New Murine Model of Islet Xenograft Rejection : Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages

Peter Schmidt, Henrik Krook, Akira Maeda, Olle Korsgren, Birgitta Benda

Diabetes 2003;52(5):1111–1118

DOI: https://doi.org/10.2337/diabetes.52.5.1111

Published: 01 May 2003

View article titled, A New Murine Model of Islet Xenograft Rejection : <span class="subtitle">Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages</span>

Journal Articles

A Distinct Th1 Immune Response Precedes the Described Th2 Response in Islet Xenograft Rejection

Henrik Krook, Anette Hagberg, Zhenshun Song, Ulf Landegren, Lars Wennberg, Olle Korsgren

Diabetes 2002;51(1):79–86

DOI: https://doi.org/10.2337/diabetes.51.1.79

Published: 01 January 2002

View article titled, A Distinct Th1 Immune Response Precedes the Described Th2 Response in Islet Xenograft Rejection

Meeting Abstracts

A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts.

T Friedman, R N Smith, R B Colvin, J Iacomini

Diabetes 1999;48(12):2340–2348

DOI: https://doi.org/10.2337/diabetes.48.12.2340

Published: 01 December 1999

View article titled, A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts.

Journal Articles

Prolonged Survival of Rat Islet and Skin Xenografts in Mice Treated with Donor Splenocytes and Anti-CD154 Monoclonal Antibody

Ethel J Gordon, Thomas G Markees, Nancy E Phillips, Randolph J Noelle, Leonard D Shultz, John P Mordes, Aldo A Rossini, Dale L Greiner

Diabetes 1998;47(8):1199–1206

DOI: https://doi.org/10.2337/diab.47.8.1199

Published: 01 August 1998

View article titled, Prolonged Survival of Rat Islet and Skin Xenografts in Mice Treated with Donor Splenocytes and Anti-CD154 Monoclonal Antibody

Journal Articles

Massive Isolation, Morphological and Functional Characterization, and Xenotransplantation of Bovine Pancreatic Islets

Piero Marchetti, Rosa Giannarelli, Sabrina Cosimi, Pellegrino Masiello, Alberto Coppelli, Paolo Viacava, Renzo Navalesi

Diabetes 1995;44(4):375–381

DOI: https://doi.org/10.2337/diab.44.4.375

Published: 01 April 1995

View article titled, Massive Isolation, Morphological and Functional Characterization, and Xenotransplantation of Bovine Pancreatic Islets

Journal Articles

Induction of Tolerance to Islet Xenografts in a Concordant Rat-to-Mouse Model

John A Goss, Yuji Nakafusa, Edward H Finke, M Wayne Flye, Paul E Lacy

Diabetes 1994;43(1):16–23

DOI: https://doi.org/10.2337/diab.43.1.16

Published: 01 January 1994

View article titled, Induction of Tolerance to Islet Xenografts in a Concordant Rat-to-Mouse Model

Journal Articles

Tumor Necrosis Factor-α Prevents Rejection of Islet Xenografts (Rat to Mouse)

Andriani Gerasimidi, Kathleen C Sheehan, Robert D Schreiber, Paul E Lacy

Diabetes 1993;42(5):651–657

DOI: https://doi.org/10.2337/diab.42.5.651

Published: 01 May 1993

View article titled, Tumor Necrosis Factor-α Prevents Rejection of Islet Xenografts (Rat to Mouse)

NARROW

2289-PUB: Comparison of GalT-KO Porcine Islet Xenograft Survival between Microcapsule against Hypoxia and Microcapsule against Fibrosis in Diabetic Mice Model

263-OR: IgM Therapy Reverses Autoimmune Diabetes and Prevents Islet Allo- and Xenotransplant Rejection

Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Erratum. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61: 1180–1191

Response to Comment on Yi et al. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180–1191

Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts

Clinical Islet Xenotransplantation: How Close Are We?

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

Short-Term Administrations of a Combination of Anti–LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

Achieving Permanent Survival of Islet Xenografts by Independent Manipulation of Direct and Indirect T-Cell Responses

Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB

Autoimmune Diabetes and Resistance to Xenograft Transplantation Tolerance in NOD Mice

The Degree of Phylogenetic Disparity of Islet Grafts Dictates the Reliance on Indirect CD4 T-Cell Antigen Recognition for Rejection

A New Murine Model of Islet Xenograft Rejection : Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages

A Distinct Th1 Immune Response Precedes the Described Th2 Response in Islet Xenograft Rejection

A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts.

Prolonged Survival of Rat Islet and Skin Xenografts in Mice Treated with Donor Splenocytes and Anti-CD154 Monoclonal Antibody

Massive Isolation, Morphological and Functional Characterization, and Xenotransplantation of Bovine Pancreatic Islets

Induction of Tolerance to Islet Xenografts in a Concordant Rat-to-Mouse Model

Tumor Necrosis Factor-α Prevents Rejection of Islet Xenografts (Rat to Mouse)

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