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Meeting Abstracts

1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

TAKAO TAKIYAMA, RYOICHI BESSHO, KAZUKI SAWAMOTO, YUMI TAKIYAMA

Diabetes 2020;69(Supplement_1):1845-P

https://doi.org/10.2337/db20-1845-P

Published: 01 June 2020

View article titled, 1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

Journal Articles

Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells

Vineeth Varanasi, Lia Avanesyan, Desiree M. Schumann, Alexander V. Chervonsky

Diabetes 2012;61(11):2862–2870

https://doi.org/10.2337/db11-1784

Published: 16 October 2012

View article titled, Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

Erratum

Diabetes 2012;61(6):1648

https://doi.org/10.2337/db12-er06a

Published: 14 May 2012

View article titled, Erratum

Journal Articles

RIG-I– and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates β-Cell Death in Fulminant Type 1 Diabetes

Kaoru Aida, Yoriko Nishida, Shoichiro Tanaka, Taro Maruyama, Akira Shimada, Takuya Awata, Masako Suzuki, Hiroki Shimura, Soichi Takizawa, Masashi Ichijo, Daiichiro Akiyama, Fumihiko Furuya, Akio Kawaguchi, Masahiro Kaneshige, Jun Itakura, Hideki Fujii, Toyoshi Endo, Tetsuro Kobayashi

Diabetes 2011;60(3):884–889

https://doi.org/10.2337/db10-0795

Published: 21 February 2011

View article titled, RIG-I– and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates β-Cell Death in Fulminant Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

Ryoichi Arita, Yasuaki Hata, Shintaro Nakao, Takeshi Kita, Muneki Miura, Shuhei Kawahara, Souska Zandi, Lama Almulki, Faryan Tayyari, Hiroaki Shimokawa, Ali Hafezi-Moghadam, Tatsuro Ishibashi

Diabetes 2009;58(1):215–226

https://doi.org/10.2337/db08-0762

Published: 01 January 2009

View article titled, Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

Journal Articles

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

Mark D. McKenzie, Emma M. Carrington, Thomas Kaufmann, Andreas Strasser, David C.S. Huang, Thomas W.H. Kay, Janette Allison, Helen E. Thomas

Diabetes 2008;57(5):1284–1292

https://doi.org/10.2337/db07-1692

Published: 01 May 2008

View article titled, Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

Fas-Associated Death Receptor Signaling Evoked by Human Amylin in Islet β-Cells

Shaoping Zhang, Hong Liu, Hua Yu, Garth J.S. Cooper

Diabetes 2008;57(2):348–356

https://doi.org/10.2337/db07-0849

Published: 01 February 2008

View article titled, Fas-Associated Death Receptor Signaling Evoked by Human Amylin in Islet β-Cells

Journal Articles

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

Nadine L. Dudek, Helen E. Thomas, Lina Mariana, Robyn M. Sutherland, Janette Allison, Eugene Estella, Eveline Angstetra, Joseph A. Trapani, Pere Santamaria, Andrew M. Lew, Thomas W.H. Kay

Diabetes 2006;55(9):2412–2418

https://doi.org/10.2337/db06-0109

Published: 01 September 2006

View article titled, Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

Journal Articles

Aging Correlates With Decreased β-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: A Potential Role for Fas and Pancreatic Duodenal Homeobox-1

Kathrin Maedler, Desiree M. Schumann, Fabienne Schulthess, José Oberholzer, Domenico Bosco, Thierry Berney, Marc Y. Donath

Diabetes 2006;55(9):2455–2462

https://doi.org/10.2337/db05-1586

Published: 01 September 2006

View article titled, Aging Correlates With Decreased β-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: <subtitle>A Potential Role for Fas and Pancreatic Duodenal Homeobox-1</subtitle>

Journal Articles

Fas Deficiency Prevents Type 1 Diabetes by Inducing Hyporesponsiveness in Islet β-Cell−Reactive T-Cells

Luis Vence, Christophe Benoist, Diane Mathis

Diabetes 2004;53(11):2797–2803

https://doi.org/10.2337/diabetes.53.11.2797

Published: 01 November 2004

View article titled, Fas Deficiency Prevents Type 1 Diabetes by Inducing Hyporesponsiveness in Islet β-Cell−Reactive T-Cells

Journal Articles

Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Dongmei Han, Xiumin Xu, David Baidal, Jenifer Leith, Camillo Ricordi, Rodolfo Alejandro, Norma S. Kenyon

Diabetes 2004;53(9):2281–2290

https://doi.org/10.2337/diabetes.53.9.2281

Published: 01 September 2004

View article titled, Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: <subtitle>Elevation Precedes Clinical Evidence of Rejection</subtitle>

Journal Articles

Virally Induced Inflammation Triggers Fratricide of Fas-Ligand–Expressing β-Cells

Urs Christen, Rima Darwiche, Helen E. Thomas, Tom Wolfe, Evelyn Rodrigo, Alexander Chervonsky, Richard A. Flavell, Matthias G. von Herrath

Diabetes 2004;53(3):591–596

https://doi.org/10.2337/diabetes.53.3.591

Published: 01 March 2004

View article titled, Virally Induced Inflammation Triggers Fratricide of Fas-Ligand–Expressing β-Cells

Journal Articles

DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

Yulian Wu, Bing Han, Hongyu Luo, Raphael Roduit, Theodora W. Salcedo, Paul A. Moore, Jun Zhang, Jiangping Wu

Diabetes 2003;52(9):2279–2286

https://doi.org/10.2337/diabetes.52.9.2279

Published: 01 September 2003

View article titled, DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

Journal Articles

Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

Maki Nakayama, Masao Nagata, Hisafumi Yasuda, Kenji Arisawa, Reiko Kotani, Katsumi Yamada, Shahead Ali Chowdhury, Sagarika Chakrabarty, Zhen Zi Jin, Hideo Yagita, Koichi Yokono, Masato Kasuga

Diabetes 2002;51(5):1391–1397

https://doi.org/10.2337/diabetes.51.5.1391

Published: 01 May 2002

View article titled, Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

Journal Articles

Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates

Dongmei Han, Xiumin Xu, Ricardo L. Pastori, Camillo Ricordi, Norma S. Kenyon

Diabetes 2002;51(3):562–566

https://doi.org/10.2337/diabetes.51.3.562

Published: 01 March 2002

View article titled, Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates

Journal Articles

Glucose Induces β-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets

Kathrin Maedler, Giatgen A. Spinas, Roger Lehmann, Pavel Sergeev, Markus Weber, Adriano Fontana, Nurit Kaiser, Marc Y. Donath

Diabetes 2001;50(8):1683–1690

https://doi.org/10.2337/diabetes.50.8.1683

Published: 01 August 2001

View article titled, Glucose Induces β-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets

Meeting Abstracts

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.

A C Loweth, G T Williams, R F James, J H Scarpello, N G Morgan

Diabetes 1998;47(5):727–732

https://doi.org/10.2337/diabetes.47.5.727

Published: 01 May 1998

View article titled, Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.

NARROW

1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring

Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells

Erratum

RIG-I– and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates β-Cell Death in Fulminant Type 1 Diabetes

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

Fas-Associated Death Receptor Signaling Evoked by Human Amylin in Islet β-Cells

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

Aging Correlates With Decreased β-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: A Potential Role for Fas and Pancreatic Duodenal Homeobox-1

Fas Deficiency Prevents Type 1 Diabetes by Inducing Hyporesponsiveness in Islet β-Cell−Reactive T-Cells

Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Virally Induced Inflammation Triggers Fratricide of Fas-Ligand–Expressing β-Cells

DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates

Glucose Induces β-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.

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