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Meeting Abstracts

110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

SAMUEL I. BLUM, YI-GUANG CHEN, HUBERT M. TSE

Diabetes 2021;70(Supplement_1):110-OR

https://doi.org/10.2337/db21-110-OR

Published: 01 June 2021

View article titled, 110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

Meeting Abstracts

1706-P: A Promoter Variant of TYK2, a Putative Virus-Induced Susceptibility Gene, Is Associated with Impaired Insulin Secretion and Nonobese Type 2 Diabetes

HITOE MORI, HIROKAZU TAKAHASHI, KEIICHIRO MINE, KANAKO INOUE, MOTOYASU KOJIMA, SHIGETAKA KUROKI, YASUHIRO ONO, SADATAKA INUZUKA, SEIHO NAGAFUCHI, KEIZO ANZAI

Diabetes 2019;68(Supplement_1):1706-P

https://doi.org/10.2337/db19-1706-P

Published: 01 June 2019

View article titled, 1706-P: A Promoter Variant of TYK2, a Putative Virus-Induced Susceptibility Gene, Is Associated with Impaired Insulin Secretion and Nonobese Type 2 Diabetes

Meeting Abstracts

1177-P: Discovery of New Therapeutic Antibodies to Two Metabolically Relevant Targets—GPCR CB1 and Transporter GLUT4—Using Virus-Like Particles

DAVID TUCKER, TOM CHARPENTIER, NICHOLAS MOLINO, ERIN ROSENBERG, BRAD SCRENCI, LEWIS J. STAFFORD, CHIDANANDA SULLI, ROSS CHAMBERS, BENJAMIN J. DORANZ, JOSEPH B. RUCKER

Diabetes 2019;68(Supplement_1):1177-P

https://doi.org/10.2337/db19-1177-P

Published: 01 June 2019

View article titled, 1177-P: Discovery of New Therapeutic Antibodies to Two Metabolically Relevant Targets—GPCR CB1 and Transporter GLUT4—Using Virus-Like Particles

Journal Articles

A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats

Natasha Qaisar, Suvana Lin, Glennice Ryan, Chaoxing Yang, Sarah R. Oikemus, Michael H. Brodsky, Rita Bortell, John P. Mordes, Jennifer P. Wang

Diabetes 2017;66(1):145–157

https://doi.org/10.2337/db16-0462

Published: 07 October 2016

View article titled, A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats

Includes: Supplementary data

Journal Articles

miR, miR in the Cell, Does the Virus Control Them All?

Sarah J. Richardson, Marc S. Horwitz

Diabetes 2016;65(4):823–825

https://doi.org/10.2337/dbi15-0039

Published: 17 March 2016

View article titled, miR, miR in the Cell, Does the Virus Control Them All?

Journal Articles

Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays

Xiaofang Bian, Garrick Wallstrom, Amy Davis, Jie Wang, Jin Park, Andrea Throop, Jason Steel, Xiaobo Yu, Clive Wasserfall, Desmond Schatz, Mark Atkinson, Ji Qiu, Joshua LaBaer

Diabetes 2016;65(1):285–296

https://doi.org/10.2337/db15-0179

Published: 08 October 2015

View article titled, Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays

Includes: Supplementary data

Journal Articles

Reduced Expression of the MDA5 Gene IFIH1 Prevents Autoimmune Diabetes

Pamela J. Lincez, Iryna Shanina, Marc S. Horwitz

Diabetes 2015;64(6):2184–2193

https://doi.org/10.2337/db14-1223

Published: 15 January 2015

View article titled, Reduced Expression of the MDA5 Gene IFIH1 Prevents Autoimmune Diabetes

Includes: Supplementary data

Journal Articles

Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

Lars Krogvold, Bjørn Edwin, Trond Buanes, Gun Frisk, Oskar Skog, Mahesh Anagandula, Olle Korsgren, Dag Undlien, Morten C. Eike, Sarah J. Richardson, Pia Leete, Noel G. Morgan, Sami Oikarinen, Maarit Oikarinen, Jutta E. Laiho, Heikki Hyöty, Johnny Ludvigsson, Kristian F. Hanssen, Knut Dahl-Jørgensen

Diabetes 2015;64(5):1682–1687

https://doi.org/10.2337/db14-1370

Published: 24 November 2014

View article titled, Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Enteroviral Infections and Development of Type 1 Diabetes: The Brothers Karamazov Within the CVBs

Francesco Dotta, Guido Sebastiani

Diabetes 2014;63(2):384–386

https://doi.org/10.2337/db13-1441

Published: 16 January 2014

View article titled, Enteroviral Infections and Development of Type 1 Diabetes: The Brothers Karamazov Within the CVBs

Journal Articles

Coxsackievirus B1 Is Associated With Induction of β-Cell Autoimmunity That Portends Type 1 Diabetes

Olli H. Laitinen, Hanna Honkanen, Outi Pakkanen, Sami Oikarinen, Minna M. Hankaniemi, Heini Huhtala, Tanja Ruokoranta, Valérie Lecouturier, Philippe André, Raimo Harju, Suvi M. Virtanen, Jussi Lehtonen, Jeffrey W. Almond, Tuula Simell, Olli Simell, Jorma Ilonen, Riitta Veijola, Mikael Knip, Heikki Hyöty

Diabetes 2014;63(2):446–455

https://doi.org/10.2337/db13-0619

Published: 16 January 2014

View article titled, Coxsackievirus B1 Is Associated With Induction of β-Cell Autoimmunity That Portends Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes

Diabetes 2014;63(2):655–662

https://doi.org/10.2337/db13-0620

Published: 16 January 2014

View article titled, Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes

Journal Articles

Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model

Ken T. Coppieters, Natalie Amirian, Philippe P. Pagni, Carmen Baca Jones, Anna Wiberg, Stanley Lasch, Edith Hintermann, Urs Christen, Matthias G. von Herrath

Diabetes 2013;62(7):2492–2499

https://doi.org/10.2337/db12-1370

Published: 14 June 2013

View article titled, Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model

Includes: Supplementary data

Journal Articles

Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

Maarit Oikarinen, Sisko Tauriainen, Sami Oikarinen, Teemu Honkanen, Pekka Collin, Immo Rantala, Markku Mäki, Katri Kaukinen, Heikki Hyöty

Diabetes 2012;61(3):687–691

https://doi.org/10.2337/db11-1157

Published: 13 February 2012

View article titled, Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

Includes: Supplementary data

Journal Articles

Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells

Barbara M. Schulte, Matthijs Kramer, Marleen Ansems, Kjerstin H.W. Lanke, Neeltje van Doremalen, Jon D. Piganelli, Rita Bottino, Massimo Trucco, Jochem M.D. Galama, Gosse J. Adema, Frank J.M. van Kuppeveld

Diabetes 2010;59(5):1182–1191

https://doi.org/10.2337/db09-1071

Published: 13 January 2010

View article titled, Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells

Includes: Supplementary data

Journal Articles

Infection With Viruses From Several Families Triggers Autoimmune Diabetes in LEW.1WR1 Rats: Prevention of Diabetes by Maternal Immunization

Rebecca S. Tirabassi, Dennis L. Guberski, Elizabeth P. Blankenhorn, Jean H. Leif, Bruce A. Woda, Zhijun Liu, Donald Winans, Dale L. Greiner, John P. Mordes

Diabetes 2010;59(1):110–118

https://doi.org/10.2337/db09-0255

Published: 30 September 2009

View article titled, Infection With Viruses From Several Families Triggers Autoimmune Diabetes in LEW.1WR1 Rats: <subtitle>Prevention of Diabetes by Maternal Immunization</subtitle>

Includes: Supplementary data

Journal Articles

Virus-Induced Autoimmune Diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex

Elizabeth P. Blankenhorn, Laura Cort, Dale L. Greiner, Dennis L. Guberski, John P. Mordes

Diabetes 2009;58(12):2930–2938

https://doi.org/10.2337/db09-0387

Published: 31 August 2009

View article titled, Virus-Induced Autoimmune Diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex

Includes: Supplementary data

Journal Articles

Viral Trigger for Type 1 Diabetes: Pros and Cons

Christophe M. Filippi, Matthias G. von Herrath

Diabetes 2008;57(11):2863–2871

https://doi.org/10.2337/db07-1023

Published: 01 November 2008

View article titled, Viral Trigger for Type 1 Diabetes: <subtitle>Pros and Cons</subtitle>

Journal Articles

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

Yael Bar, Holger A. Russ, Sarah Knoller, Limor Ouziel-Yahalom, Shimon Efrat

Diabetes 2008;57(9):2413–2420

https://doi.org/10.2337/db07-1323

Published: 01 September 2008

View article titled, HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

Includes: Supplementary data

Journal Articles

Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36

Pamela M. Rogers, Nazar Mashtalir, Miloni A. Rathod, Olga Dubuisson, Zhong Wang, Kumar Dasuri, Scott Babin, Alok Gupta, Nathan Markward, William T. Cefalu, Nikhil V. Dhurandhar

Diabetes 2008;57(9):2321–2331

https://doi.org/10.2337/db07-1311

Published: 01 September 2008

View article titled, Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36

Includes: Supplementary data

Journal Articles

In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

Holger A. Russ, Yael Bar, Philippe Ravassard, Shimon Efrat

Diabetes 2008;57(6):1575–1583

https://doi.org/10.2337/db07-1283

Published: 01 June 2008

View article titled, In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

Includes: Supplementary data

NARROW

110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

1706-P: A Promoter Variant of TYK2, a Putative Virus-Induced Susceptibility Gene, Is Associated with Impaired Insulin Secretion and Nonobese Type 2 Diabetes

1177-P: Discovery of New Therapeutic Antibodies to Two Metabolically Relevant Targets—GPCR CB1 and Transporter GLUT4—Using Virus-Like Particles

A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats

miR, miR in the Cell, Does the Virus Control Them All?

Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays

Reduced Expression of the MDA5 Gene IFIH1 Prevents Autoimmune Diabetes

Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

Enteroviral Infections and Development of Type 1 Diabetes: The Brothers Karamazov Within the CVBs

Coxsackievirus B1 Is Associated With Induction of β-Cell Autoimmunity That Portends Type 1 Diabetes

Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes

Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model

Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells

Infection With Viruses From Several Families Triggers Autoimmune Diabetes in LEW.1WR1 Rats: Prevention of Diabetes by Maternal Immunization

Virus-Induced Autoimmune Diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex

Viral Trigger for Type 1 Diabetes: Pros and Cons

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36

In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

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