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Search Results for apo-apolipoprotein
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in Circulating MicroRNAs to Predict the Risk for Metabolic Diseases in the General Population? > Diabetes
Published: 14 February 2017
Figure 1 Summary of the study design and findings reported in Willeit et al. ( 11 ). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1; Mttp, microsomal triglyceride transfer protein; TG, triglyceride. Figure 1. Summary of the study design and findings reported in Willeit et al. (11). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1; Mttp, microsomal triglyceride transfer protein; TG, triglyceride. More
in Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance–Associated Iron Overload > Diabetes
Published: 01 July 2008
FIG. 5. A: Effects of lactoferrin (LTF), apolipoprotein-transferrin (Apo-TF), and holotransferrin (TF) on RBP4 release from adipose tissue explants compared with vehicle (C). B: Effects of lactoferrin (10 μmol/l) on RBP4 expression. Effects of deferoxamine (20 μmol/l) (DFO) on RBP4 release (C) and RBP4 expression in adipose tissue explants (D). FIG. 5. A: Effects of lactoferrin (LTF), apolipoprotein-transferrin (Apo-TF), and holotransferrin (TF) on RBP4 release from adipose tissue explants compared with vehicle (C). B: Effects of lactoferrin (10 μmol/l) on RBP4 expression. Effects of deferoxamine (20 μmol/l) (DFO) on RBP4 release (C) and RBP4 expression in adipose tissue explants (D). More
Published: 01 December 1986
...M Eto; K Watanabe; Y Iwashima; A Morikawa; E Oshima; M Sekiguchi; K Ishii The relationship between apolipoprotein E (apoE) polymorphism and plasma lipids and hyperlipemia was investigated in 105 male type II diabetics and 111 male nondiabetics. ApoE phenotypes were determined by a one-dimensional...
Published: 01 July 1996
... and are available to study the pathophysiology of human diseases, including atherosclerosis, diabetes, and hyperlipidemia. We have established transgenic mouse lines with an integrated rat apolipoprotein (apo) E gene under control of the metallothionein promoter. Overexpression of apoE in the liver reduced plasma...
Kyoko Kogawa, Yoshiki Nishizawa, Masayuki Hosoi, Takahiko Kawagishi, Kiyoshi Maekawa, Tetsuo Shoji, Yasuhisa Okuno, Hirotoshi Morii
Published: 01 April 1997
...Kyoko Kogawa; Yoshiki Nishizawa; Masayuki Hosoi; Takahiko Kawagishi; Kiyoshi Maekawa; Tetsuo Shoji; Yasuhisa Okuno; Hirotoshi Morii We examined the association between the polymorphism of the apolipoprotein E (apoE) and the ACE genes and the intima-media thickness (IMT) of the carotid and femoral...
Stewart C. Ferguson, Ian J. Deary, Julie C. Evans, Sian Ellard, Andrew T. Hattersley, Brian M. Frier
Published: 01 January 2003
...Stewart C. Ferguson; Ian J. Deary; Julie C. Evans; Sian Ellard; Andrew T. Hattersley; Brian M. Frier The ε4 allele of the apolipoprotein-E (APOE) gene is associated with poor outcome following various cerebral insults. The relationship between APOE genotype and cognitive function in patients...
Published: 01 July 1994
...David L Rainwater; Jean W MacCluer; Michael P Stern; John L VandeBerg; Steven M Haffner We investigated the effects of non-insulin-dependent diabetes mellitus (NIDDM) on lipoprotein(a) (Lp[a]) and apolipoprotein(a) (apo[a]) in a population of Mexican-Americans. In plasma samples from 536 subjects...
Published: 01 October 1992
... for these lipoproteins. Further studies LPL, lipoprotein lipase; apoE, apolipoprotein E; LDL, low-density lipopro- tein; VLDL, very-low-density lipoprotein; Fc, crystallizable immunoglobulin fragment. DIABETES, VOL. 41, SUPPL. 2, OCTOBER 1992 77 MACROPHAGE LPL AND ApoE demonstrated, however, that the LDL receptor was re...
Jonathan Q Purnell, Santica M Marcovina, John E Hokanson, Hal Kennedy, Patricia A Cleary, Michael W Steffes, John D Brunzell
Published: 01 October 1995
...Jonathan Q Purnell; Santica M Marcovina; John E Hokanson; Hal Kennedy; Patricia A Cleary; Michael W Steffes; John D Brunzell Levels of lipoprotein(a) [Lp(a)], apolipoprotein (apo) B, and lipoprotein cholesterol distribution using density-gradient ultracentrifugation were measured as part of a cross...
Published: 14 February 2017
...Figure 1 Summary of the study design and findings reported in Willeit et al. ( 11 ). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1...
Yutaka Harano, Aritsune Kageyama, Yasuhiko Nakao, Yasushi Hara, Masaaki Suzuki, Akira Sato, Motoyoshi Ikebuchi, Kazuya Shinozaki, Motoo Tsushima
Published: 01 July 1996
...Yutaka Harano; Aritsune Kageyama; Yasuhiko Nakao; Yasushi Hara; Masaaki Suzuki; Akira Sato; Motoyoshi Ikebuchi; Kazuya Shinozaki; Motoo Tsushima Cholesterol, triglylceride (TG), and apolipoprotein (apo) B were determined in plasma and in lipoprotein subtractions (VLDL, intermediate-density...
Published: 01 May 2000
.... In this study, we have identified HNF-4alpha target genes that are mainly expressed in the liver, including alpha1-antitrypsin, alpha1-antichymotrypsin, alpha-fetal protein, ceruloplasmin, IGF binding protein 1, transferrin, apolipoprotein(AI) [apo(AI)], apo(AII), apo(B), and apo(CIII). Serum levels...
Geesje M. Dallinga-Thie, Arie van Tol, Hiroaki Hattori, Patrick C.N. Rensen, Eric J.G. Sijbrands, for the Diabetes Atorvastatin Lipid Intervention (DALI) Study Group
Published: 01 May 2006
... with diabetes, a condition with strongly elevated risk for coronary heart disease. The aim of this study was to test the hypothesis that statins reduce PLTP activity and to examine the potential role of apolipoprotein E (apoE). PLTP activity and apoE were measured in patients with type 2 diabetes from the DALI...
Published: 01 December 2006
...Zhi Hua Huang; Catherine A. Reardon; Theodore Mazzone Apolipoprotein E (apoE) is highly expressed in adipose tissue and adipocytes in which its expression is regulated by peroxisome proliferator–activated receptor (PPAR)-γ agonists and tumor necrosis factor–α. There is, however, no information...
Robin P F Dullaart, Klaas Hoogenberg, Stephen C Riemens, Johanna E M Groener, Arie van Tol, Wim J Sluiter, Ben K Stulp
Published: 01 December 1997
..., apolipoprotein (apo) E genotype, serum lipoproteins, serum CETP activity (measured with an exogenous substrate assay, n = 30), clinical variables, and a diet history were documented. The 1-year response to diet was assessed in 14 type 1 diabetic patients, including 6 B1B1 and 6 B1B2...
Monika Zoltowska, Ehud Ziv, Edgard Delvin, Daniel Sinnett, Ronny Kalman, Carole Garofalo, Ernest Seidman, Emile Levy
Published: 01 October 2003
... and diabetes on intestinal fat transport. The aim of the present study was to examine intracellular events that govern lipid transport and apolipoprotein (apo) B-48-containing lipoprotein assembly in the small intestine of Psammomys obesus, a model of nutritionally induced insulin resistance and type...
Susanna M. Hofmann, Diego Perez-Tilve, Todd M. Greer, Beth A. Coburn, Erin Grant, Joshua E. Basford, Matthias H. Tschöp, David Y. Hui
Published: 01 January 2008
...Susanna M. Hofmann; Diego Perez-Tilve; Todd M. Greer; Beth A. Coburn; Erin Grant; Joshua E. Basford; Matthias H. Tschöp; David Y. Hui OBJECTIVE— Apolipoprotein E (ApoE) regulates plasma lipid levels via modulation of lipolysis and serving as ligand for receptor-mediated clearance of triglyceride...
Includes: Supplementary data
Koji Yamamoto, Hitoshi Shimano, Masako Shimada, Masako Kawamura, Takanari Gotoda, Kenji Harada, Jun-ichi Ohsuga, Yoshi Yazaki, Nobuhiro Yamada
Published: 01 May 1995
...Koji Yamamoto; Hitoshi Shimano; Masako Shimada; Masako Kawamura; Takanari Gotoda; Kenji Harada; Jun-ichi Ohsuga; Yoshi Yazaki; Nobuhiro Yamada To determine the role of apolipoprotein E (apoE) in diabetic hyperlipidemia, we induced diabetes in transgenic mice overexpressing apoE by intravenous...
Tahseen A Chowdhury, Philip H Dyer, Sudesh Kumar, Simon P Gibson, Bethan R Rowe, Simon J Davies, Sally M Marshall, Peter J Morris, Geoffrey V Gill, Susan Feeney, Peter Maxwell, David Savage, Andrew J M Boulton, John A Todd, David Dunger, Anthony H Barnett, Stephen C Bain
Published: 01 February 1998
.... Apolipoprotein E (apoE) is a major protein con- inclusion criteria in the nephropathy cohort. DNA was stituent of lipoproteins, mediating hepatic lipoprotein uptake extracted from peripheral blood leukocytes by the Nucleon and reverse cholesterol transport. ApoE occurs as three iso- method (Scotlab, Paisley...
Published: 01 December 2000
...S Araki; D K Moczulski; L Hanna; L J Scott; J H Warram; A S Krolewski The goal of this study was to examine the association between known polymorphisms in the apolipoprotein E gene (APOE) and diabetic nephropathy (DN) in type 1 diabetes. We used both a case-control comparison and a family-based...