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apo-apolipoprotein

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Summary of the study design and findings reported in Willeit et al. ( 11 )....
Published: 14 February 2017
Figure 1 Summary of the study design and findings reported in Willeit et al. ( 11 ). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1; Mttp, microsomal triglyceride transfer protein; TG, triglyceride. Figure 1. Summary of the study design and findings reported in Willeit et al. (11). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1; Mttp, microsomal triglyceride transfer protein; TG, triglyceride. More
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<em>A</em>: Effects of lactoferrin (LTF), <span class="search-highlight">apolipoprotein</span>-transferri...
Published: 01 July 2008
FIG. 5. A: Effects of lactoferrin (LTF), apolipoprotein-transferrin (Apo-TF), and holotransferrin (TF) on RBP4 release from adipose tissue explants compared with vehicle (C). B: Effects of lactoferrin (10 μmol/l) on RBP4 expression. Effects of deferoxamine (20 μmol/l) (DFO) on RBP4 release (C) and RBP4 expression in adipose tissue explants (D). FIG. 5. A: Effects of lactoferrin (LTF), apolipoprotein-transferrin (Apo-TF), and holotransferrin (TF) on RBP4 release from adipose tissue explants compared with vehicle (C). B: Effects of lactoferrin (10 μmol/l) on RBP4 expression. Effects of deferoxamine (20 μmol/l) (DFO) on RBP4 release (C) and RBP4 expression in adipose tissue explants (D). More
Journal Articles
Journal: Diabetes
Diabetes 1986;35(12):1374–1382
Published: 01 December 1986
...M Eto; K Watanabe; Y Iwashima; A Morikawa; E Oshima; M Sekiguchi; K Ishii The relationship between apolipoprotein E (apoE) polymorphism and plasma lipids and hyperlipemia was investigated in 105 male type II diabetics and 111 male nondiabetics. ApoE phenotypes were determined by a one-dimensional...
Journal Articles
Journal: Diabetes
Diabetes 1996;45(Supplement_3):S129–S132
Published: 01 July 1996
... and are available to study the pathophysiology of human diseases, including atherosclerosis, diabetes, and hyperlipidemia. We have established transgenic mouse lines with an integrated rat apolipoprotein (apo) E gene under control of the metallothionein promoter. Overexpression of apoE in the liver reduced plasma...
Journal Articles
Journal: Diabetes
Diabetes 1997;46(4):682–687
Published: 01 April 1997
...Kyoko Kogawa; Yoshiki Nishizawa; Masayuki Hosoi; Takahiko Kawagishi; Kiyoshi Maekawa; Tetsuo Shoji; Yasuhisa Okuno; Hirotoshi Morii We examined the association between the polymorphism of the apolipoprotein E (apoE) and the ACE genes and the intima-media thickness (IMT) of the carotid and femoral...
Journal Articles
Journal: Diabetes
Diabetes 2003;52(1):145–148
Published: 01 January 2003
...Stewart C. Ferguson; Ian J. Deary; Julie C. Evans; Sian Ellard; Andrew T. Hattersley; Brian M. Frier The ε4 allele of the apolipoprotein-E (APOE) gene is associated with poor outcome following various cerebral insults. The relationship between APOE genotype and cognitive function in patients...
Journal Articles
Journal: Diabetes
Diabetes 1994;43(7):942–946
Published: 01 July 1994
...David L Rainwater; Jean W MacCluer; Michael P Stern; John L VandeBerg; Steven M Haffner We investigated the effects of non-insulin-dependent diabetes mellitus (NIDDM) on lipoprotein(a) (Lp[a]) and apolipoprotein(a) (apo[a]) in a population of Mexican-Americans. In plasma samples from 536 subjects...
Journal Articles
Journal: Diabetes
Diabetes 1992;41(Supplement_2):77–80
Published: 01 October 1992
... for these lipoproteins. Further studies LPL, lipoprotein lipase; apoE, apolipoprotein E; LDL, low-density lipopro- tein; VLDL, very-low-density lipoprotein; Fc, crystallizable immunoglobulin fragment. DIABETES, VOL. 41, SUPPL. 2, OCTOBER 1992 77 MACROPHAGE LPL AND ApoE demonstrated, however, that the LDL receptor was re...
Journal Articles
Journal: Diabetes
Diabetes 1995;44(10):1218–1226
Published: 01 October 1995
...Jonathan Q Purnell; Santica M Marcovina; John E Hokanson; Hal Kennedy; Patricia A Cleary; Michael W Steffes; John D Brunzell Levels of lipoprotein(a) [Lp(a)], apolipoprotein (apo) B, and lipoprotein cholesterol distribution using density-gradient ultracentrifugation were measured as part of a cross...
Journal Articles
Journal: Diabetes
Diabetes 2017;66(3):565–567
Published: 14 February 2017
...Figure 1 Summary of the study design and findings reported in Willeit et al. ( 11 ). Acly, ATP citrate lyase; APO, apolipoprotein; CPT1, carnitine palmitoyltransferase I; HINT1, histidine triad nucleotide binding protein 1; LRP1, low-density lipoprotein receptor-related protein 1...
Journal Articles
Journal: Diabetes
Diabetes 1996;45(Supplement_3):S31–S34
Published: 01 July 1996
...Yutaka Harano; Aritsune Kageyama; Yasuhiko Nakao; Yasushi Hara; Masaaki Suzuki; Akira Sato; Motoyoshi Ikebuchi; Kazuya Shinozaki; Motoo Tsushima Cholesterol, triglylceride (TG), and apolipoprotein (apo) B were determined in plasma and in lipoprotein subtractions (VLDL, intermediate-density...
Meeting Abstracts
Journal: Diabetes
Diabetes 2000;49(5):832–837
Published: 01 May 2000
.... In this study, we have identified HNF-4alpha target genes that are mainly expressed in the liver, including alpha1-antitrypsin, alpha1-antichymotrypsin, alpha-fetal protein, ceruloplasmin, IGF binding protein 1, transferrin, apolipoprotein(AI) [apo(AI)], apo(AII), apo(B), and apo(CIII). Serum levels...
Journal Articles
Journal: Diabetes
Diabetes 2006;55(5):1491–1496
Published: 01 May 2006
... with diabetes, a condition with strongly elevated risk for coronary heart disease. The aim of this study was to test the hypothesis that statins reduce PLTP activity and to examine the potential role of apolipoprotein E (apoE). PLTP activity and apoE were measured in patients with type 2 diabetes from the DALI...
Journal Articles
Journal: Diabetes
Diabetes 2006;55(12):3394–3402
Published: 01 December 2006
...Zhi Hua Huang; Catherine A. Reardon; Theodore Mazzone Apolipoprotein E (apoE) is highly expressed in adipose tissue and adipocytes in which its expression is regulated by peroxisome proliferator–activated receptor (PPAR)-γ agonists and tumor necrosis factor–α. There is, however, no information...
Journal Articles
Journal: Diabetes
Diabetes 1997;46(12):2082–2087
Published: 01 December 1997
..., apolipoprotein (apo) E genotype, serum lipoproteins, serum CETP activity (measured with an exogenous substrate assay, n = 30), clinical variables, and a diet history were documented. The 1-year response to diet was assessed in 14 type 1 diabetic patients, including 6 B1B1 and 6 B1B2...
Journal Articles
Journal: Diabetes
Diabetes 2003;52(10):2539–2545
Published: 01 October 2003
... and diabetes on intestinal fat transport. The aim of the present study was to examine intracellular events that govern lipid transport and apolipoprotein (apo) B-48-containing lipoprotein assembly in the small intestine of Psammomys obesus, a model of nutritionally induced insulin resistance and type...
Journal Articles
Journal: Diabetes
Diabetes 2008;57(1):5–12
Published: 01 January 2008
...Susanna M. Hofmann; Diego Perez-Tilve; Todd M. Greer; Beth A. Coburn; Erin Grant; Joshua E. Basford; Matthias H. Tschöp; David Y. Hui OBJECTIVE— Apolipoprotein E (ApoE) regulates plasma lipid levels via modulation of lipolysis and serving as ligand for receptor-mediated clearance of triglyceride...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 1995;44(5):580–585
Published: 01 May 1995
...Koji Yamamoto; Hitoshi Shimano; Masako Shimada; Masako Kawamura; Takanari Gotoda; Kenji Harada; Jun-ichi Ohsuga; Yoshi Yazaki; Nobuhiro Yamada To determine the role of apolipoprotein E (apoE) in diabetic hyperlipidemia, we induced diabetes in transgenic mice overexpressing apoE by intravenous...
Journal Articles
Journal: Diabetes
Diabetes 1998;47(2):278–280
Published: 01 February 1998
.... Apolipoprotein E (apoE) is a major protein con- inclusion criteria in the nephropathy cohort. DNA was stituent of lipoproteins, mediating hepatic lipoprotein uptake extracted from peripheral blood leukocytes by the Nucleon and reverse cholesterol transport. ApoE occurs as three iso- method (Scotlab, Paisley...
Meeting Abstracts
Journal: Diabetes
Diabetes 2000;49(12):2190–2195
Published: 01 December 2000
...S Araki; D K Moczulski; L Hanna; L J Scott; J H Warram; A S Krolewski The goal of this study was to examine the association between known polymorphisms in the apolipoprotein E gene (APOE) and diabetic nephropathy (DN) in type 1 diabetes. We used both a case-control comparison and a family-based...