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hpfs-health-professionals-follow-study

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Journal Articles
Journal: Diabetes
Diabetes 2017;66(10):2704–2712
Published: 12 July 2017
...-term BMI change. In addition, we particularly examined the interaction between each GRS and change in physical activity on long-term BMI change in two independent cohorts: the Nurses’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). The NHS is a cohort of 121,701 female...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2010;59(5):1239–1243
Published: 25 February 2010
... enrolled in the Health Professionals Follow-Up Study (HPFS) and Nurses' Health Study (NHS). Participants were free of all cardiovascular disease and cancer at baseline. RESULTS During 10 years of follow-up among men and 14 years among women, we documented 178 and 146 cases of CHD, respectively. We...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2012;61(11):3026–3032
Published: 16 October 2012
..., we constructed a genetic predisposition score on the basis of 29 high blood pressure–predisposing variants and examined the association between the genetic predisposition score and risk of CVD among men and women with T2D from the Health Professionals Follow-up Study (HPFS) and Nurses’ Health Study...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2015;64(9):3146–3154
Published: 22 May 2015
... at the HIF3A locus in relation to BMI and 10-year changes in BMI in two prospective cohorts: the Nurses’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). Corresponding author: Lu Qi, nhlqi@channing.harvard.edu . 25 02 2015 14 05 2015 © 2015 by the American Diabetes...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2006;55(9):2645–2648
Published: 01 September 2006
... of the TCF7L2 gene and the risk of type 2 diabetes in two large well-established cohorts: the Nurses’ Health Study (NHS) and the Health Professionals Follow-up Study (HPFS). Furthermore, we evaluated whether this relationship was modulated by conventional risk factors for type 2 diabetes. Heterogeneity...
Journal Articles
Journal: Diabetes
Diabetes 2020;69(9):1917–1926
Published: 03 June 2020
... and central adiposity were significantly modified by weight-loss diets varying in carbohydrate intakes. The current study included a total of 32,054 adults (17,171 women and 14,883 men) from four large-scale prospective cohort studies: the Nurses’ Health Study (NHS), the Health Professionals Follow...
Journal Articles
Journal: Diabetes
Diabetes 2007;56(9):2388–2394
Published: 01 September 2007
... Care, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, Netherlands. E-mail: j.beulens@umcutrecht.nl 25 5 2007 9 2 2007 DIABETES 2007 ADH, alcohol dehydrogenase HPFS, Health Professionals Follow-Up Study NHS, Nurses’ Health Study Moderate alcohol...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2018;67(2):248–255
Published: 06 December 2017
...’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). The NHS enrolled 121,700 female registered nurses aged 30–55 years in 1976, and the HPFS enrolled 51,529 male professionals aged 40–75 years in 1986. In both cohorts, follow-up questionnaires were mailed to participants...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2012;61(3):745–752
Published: 13 February 2012
... prospective cohorts: the Nurses’ Health Study (NHS) and Health Professionals Follow-up Study (HPFS). The NHS is a prospective cohort study of 121,700 female registered nurses who were aged 30–55 years at study inception in 1976 when all of them completed a mailed questionnaire on their medical history...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2008;57(11):3145–3151
Published: 01 November 2008
... on their medical history and lifestyle ( 17 ). Between 1989 and 1990, 32,826 women provided blood samples. The Health Professional Follow-Up Study (HPFS) is a prospective cohort study of 51,529 U.S. male health professionals aged 40–75 years at study initiation in 1986 ( 18 ). Between 1993 and 1999, 18,159 men...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2011;60(1):74–79
Published: 28 September 2010
... with higher type 2 diabetes risk. To accomplish these aims, we examined men enrolled in the Health Professionals Follow-Up Study (HPFS), an ongoing prospective cohort of men who have repeatedly reported their alcohol consumption over time and in whom validated diagnoses of diabetes have been ascertained...
Journal Articles
Journal: Diabetes
Diabetes 2011;60(8):2197–2201
Published: 18 July 2011
... in a nested case-control study of type 2 diabetes ( 17 , 18 ). To test the association with diabetes risk, we also included a nested case-control study in the Health Professional Follow-up Study (HPFS) ( 17 ) ( Supplementary Materials ). Family and twin studies indicate that 30–88% variance...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2005;54(5):1607–1610
Published: 01 May 2005
... sought to examine the associations of the variability of APM1 gene and CVD risk in a larger prospective cohort of diabetic men from the Health ProfessionalsFollow-up Study (HPFS). We also examined the effects of the APM1 variants on the plasma levels of adiponectin and other...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2018;67(2):167–168
Published: 16 January 2018
... of either the Nurses’ Health Study (NHS) or the Health Professionals Follow-Up Study (HPFS). All individuals provided BMI measurements over many years and also early on provided a blood sample for genotyping. Then based on a series of 97 single nucleotide polymorphisms linked to BMI, the authors calculated...
Journal Articles
Journal: Diabetes
Diabetes 2019;68(3):479–489
Published: 13 February 2019
... these genetic effects may be especially illuminating for our understanding of the etiology of atherosclerosis in diabetes. Based on this premise, we conducted a GWAS for CHD specifically among patients with T2D ( 32 ). This was a collaboration among the Nurses’ Health Study (NHS), Health Professionals Follow-Up...
Journal Articles
Journal: Diabetes
Diabetes 2017;66(10):2533–2534
Published: 13 September 2017
... to prevent obesity, particularly with individuals that are genetically predisposed to the disease, should be a key message to patients. Taking advantage of long-term follow-up data from both the Nurses’ Health Study (NHS) (∼9,400 women) and the Health Professionals Follow-Up Study (HPFS) (∼5,300 men...
Journal Articles
Journal: Diabetes
Diabetes 2018;67(1):12–22
Published: 12 December 2017
... with adiponectin levels, as well as with cardiovascular mortality, thus pointing to a direct deleterious role of adiponectin in shaping the risk of death. Completely in contrast with our data ( 58 ), Liu et al. ( 59 ) found in 950 individuals from the Health Professionals Follow-Up Study (HPFS) that adiponectin...
Journal Articles
Journal: Diabetes
Diabetes 2003;52(8):1976–1985
Published: 01 August 2003
... not observe a reduction in DC number following NF-κB ODN treatment at 10 mmol/l in the present study. These results indicate that exposure of DCs to 10 mmol/l NF-κB ODN yielded a satisfactory suppressive effect with minimal toxicity. The results of this study coincide with the view that type 1 diabetes...
Journal Articles
Journal: Diabetes
Diabetes 2015;64(7):2636–2645
Published: 02 March 2015
... between the amount of assigned food and the leftover food after 3–4 days) were recorded twice a week. Age- and sex-matched mice on SD were also followed as a control. At the end of 100 days on the HFD, the animals were killed. Rate of weight gain was monitored for the entire study period. The weight gain...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2017;66(6):1432–1442
Published: 15 May 2017
... products lowers the risk of developing T2D. The Health Professionals Follow-up Study (HPFS) assessed the relation between dairy intake and incident cases of T2D in 41,254 male participants and concluded that dietary patterns characterized by higher dairy intake, especially low-fat dairy intake, may lower...