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mln-mesenteric-lymph-node

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Proliferation of naive CFSE-labeled 8.3-CD8<sup>+</sup> T cells in lymphoid...
Published: 14 February 2013
. LN, lymph node; MLN, mesenteric lymph node; PLN, pancreatic lymph node. FIG. 4. Proliferation of naive CFSE-labeled 8.3-CD8+ T cells in lymphoid organs of IGRP206–214-competent hosts grafted with IGRP206–214-competent compared with IGRP206–214-deficient islets. A: Representative CFSE dilution More
Images
CD3 modulation is required for synergy between anti-CD3 and oral insulin tr...
Published: 14 May 2012
with oral insulin (CT). Data show the results obtained in individual mice. n = 6–12 in one representative experiment of three. MLN, mesenteric lymph node. FIG. 3. CD3 modulation is required for synergy between anti-CD3 and oral insulin treatments. A and B: In vivo TCR-αβ modulation 5, 24, and 48 More
Journal Articles
Journal: Diabetes
Diabetes 1999;48(11):2150–2156
Published: 01 November 1999
... the feeding. An increase in the levels of trans- rodents (3,4) and humans (5) in promoting disease and -cell forming growth factor- was seen after 24 h only in the destruction. Splenic T-cells from diabetic animals are able to mesenteric lymph nodes (MLN). In both of these adoptively transfer the disease...
Journal Articles
Journal: Diabetes
Diabetes 2013;62(3):905–911
Published: 14 February 2013
.... LN, lymph node; MLN, mesenteric lymph node; PLN, pancreatic lymph node. FIG. 4. Proliferation of naive CFSE-labeled 8.3-CD8+ T cells in lymphoid organs of IGRP206–214-competent hosts grafted with IGRP206–214-competent compared with IGRP206–214-deficient islets. A: Representative CFSE dilution...
Includes: Supplementary data
Images
Dendritic cell chimerism of transplanted NOD mice. Splenocytes and lymphocy...
Published: 01 June 2005
for the expression of the two CD45+ isoforms, CD45.1+ (host) and CD45.2+ (donor). More than 97% of dendritic cells in pancreatic draining lymph nodes (PLN), mesenteric lymph nodes (MLN), and spleen are donor derived. Means ± SD, n = 3. FIG. 2. Dendritic cell chimerism More
Journal Articles
Journal: Diabetes
Diabetes 1996;45(9):1173–1180
Published: 01 September 1996
... form heterodimers with the (37-chain (16). Thus, lympho- CMFDA, chloromethylfuorescein diacetate; mAb, monoclonal antibody; MAd cytes associated with mucosal tissues can be distinguished CAM-1, mucosal addressin cell adhesion molecule-1; MLN, mesenteric lymph node; by their surface phenotype from those...
Images
Frequencies of IGRP<sub>206–214</sub>-reactive CD8<sup>+</sup> T cells in l...
Published: 14 February 2013
of NRP-V7/Kd tetramer-positive cells in CD8+ T cells from lymph nodes (LNs) draining the grafted compared with contralateral kidneys (A), the pancreatic lymph nodes (PLNs) and the mesenteric lymph nodes (MLNs) (B), and the spleen (C). Data (average ± SEM More
Journal Articles
Journal: Diabetes
Diabetes 2005;54(4):1040–1047
Published: 01 April 2005
... intensity mLN, mesenteric lymph node panLN, pancreatic lymph node PE, phycoerythrin PMA, phorbol myristate acetate Autoimmune destruction of pancreatic β-cells arises as a result of a loss of tolerance. Regulatory T-cells, particularly subsets of CD4+ T-cells, are essential...
Images
Phenotype of fat-associated CD4<sup>+</sup> T cells and homing of naive T c...
Published: 17 August 2012
. C: Phenotypic analysis of transferred naive OVA-specific CD4+ T cells, after 1 week, in mesenteric lymph nodes (MLN) and in AT. D: Cytokine profiles of activated T cells by intracytoplasmic analysis for IL-4, IL-10, IL-17, and IFN-γ. The results of 3 independent experiments More
Journal Articles
Journal: Diabetes
Diabetes 2007;56(8):2103–2109
Published: 01 August 2007
...-presenting cell (APC)-labeled streptavidin, PE-conjugated anti-CD62L Ab (MEL14), PE-conjugated anti-CD45RB Ab (16A) (BD Pharmingen), and biotinylated anti-human LAP Ab (BAF246; XO02) (R&D Systems). Single-cell suspensions were prepared from spleen and mesenteric lymph node (MLN). To measure...
Journal Articles
Journal: Diabetes
Diabetes 1999;48(9):1720–1729
Published: 01 September 1999
... immunosorbent assay; FITC, fluorescein isothiocyanate; IFN, interferon; IL, interleukin; mAb, monoclonal antibody; MACS, magnetic cell sorting; MCP, monocyte chemotactic protein; MIP, macrophage inflammatory protein; MLN, mesenteric lymph node; OVA, ovalbumin; PBS, phosphate-buffered saline; PLN, pancreatic...
Journal Articles
Journal: Diabetes
Diabetes 2008;57(2):395–404
Published: 01 February 2008
... cell sorter FoB, follicular B-cell GAPDH, glyceraldehyde 3-phosphate dehydrogenase ILN, inguinal lymph node MHC, major histocompatibility complex MLN, mesenteric lymph node MZB, marginal-zone B-cell NF, nuclear factor PLN, pancreatic lymph node S1P, sphingosine-1-phosphate TLR, toll-like...
Journal Articles
Journal: Diabetes
Diabetes 2012;61(6):1490–1499
Published: 14 May 2012
... with oral insulin (CT). Data show the results obtained in individual mice. n = 6–12 in one representative experiment of three. MLN, mesenteric lymph node. FIG. 3. CD3 modulation is required for synergy between anti-CD3 and oral insulin treatments. A and B: In vivo TCR-αβ modulation 5, 24, and 48...
Includes: Supplementary data
Images
Effects of B10 <em>Idd9.1</em> on the function of naive 8.3-CD8<sup
Published: 15 October 2009
Idd9.1 donors) hosts and analyzed for dividing (CFSElow) CD8+ T-cells in pancreatic (PLN) and mesenteric (MLN) lymph nodes 6 days later. C: Representative flow cytometry profiles. D: Average quantitative data. E: Percentages and total numbers of 8.3 More
Journal Articles
Journal: Diabetes
Diabetes 2007;56(10):2561–2568
Published: 01 October 2007
... DIABETES 2007 CFSE, 5,6-carboxylfluorescein diacetate succinimidyl ester CTLA-4, cytotoxic T-cell antigen 4 EAE, experimental allergic encephalomyelitis IFN, interferon IL, interleukin JAK, janus kinase MLN, mesenteric lymph nodes MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2010;59(1):272–281
Published: 15 October 2009
... Idd9.1 donors) hosts and analyzed for dividing (CFSElow) CD8+ T-cells in pancreatic (PLN) and mesenteric (MLN) lymph nodes 6 days later. C: Representative flow cytometry profiles. D: Average quantitative data. E: Percentages and total numbers of 8.3...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 1996;45(9):1181–1186
Published: 01 September 1996
... ( ) on PBS T I B 1 2 2 MEL14 Y N / 1 . 4 R 1 - 2 M 1 7 / 5 . 2 the migration of Thyl,l T-cells to the lymphoid organs. (Three independent experiments, n = 5 for each group). The number of ** transferred T-cells present in the pancreatic (PaLN) or mesenteric (MLN) lymph nodes and spleen were determined...
Journal Articles
Journal: Diabetes
Diabetes 1992;41(3):308–312
Published: 01 March 1992
... the exocrine pancreas yields reactive islet-specific lym- (Norwalk, CT) Taq polymerase. A bulk reaction mix was phocytes and reduces the possibility of contamination prepared containing amplirag and downstream Cp with T cells from mesenteric lymph nodes or inflamed primer, without templates and Vp primers...
Journal Articles
Journal: Diabetes
Diabetes 2016;65(11):3429–3439
Published: 05 August 2016
...−/−) expressing normal PI1 and PI2 or altered PI expression levels. In the absence of PI2 (Ins2−/−), CTL in pancreatic lymph nodes (PLNs) were more activated, and male G9Cα−/− mice developed T1D. Furthermore, when the insulin-specific CTLs developed in transgenic mice lacking...
Includes: Supplementary data
Journal Articles
Journal: Diabetes
Diabetes 2014;63(8):2876–2887
Published: 17 July 2014
... combi-GAD therapy and found that combi-GAD therapy significantly decreased the frequency of CD4+ T cells and increased the frequency of CD8+ T cells in PLNs and mesenteric lymph nodes (MLNs) compared with untreated recent-onset diabetic animals ( Supplementary Table 1...
Includes: Supplementary data