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Omega-3 supplements and salmon.

Special Edition: Myth Busters: Fish Oil—Facts, Fiction, and EPA

Diabetes Core Update Special Editions logo Amarin Logo.

The idea of fish oil is one that has captured the public’s imagination. If fish like salmon, mackerel, and anchovies are a healthier protein for heart health, then surely fish oil is a convenient way to get omega-3s. But what does the evidence say about the popular dietary supplement? Join host Neil Skolnik as he sorts fact from fiction and explores the difference between omega-3 fatty acids and icosapent ethyl.

This special episode is supported by an independent educational grant from Amarin.

Please listen to the episodes by clicking on the podcast player below or by freely subscribing to Diabetes Core Update via Apple Podcasts, Amazon Music, Spotify, or your preferred podcast platform.

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Total Time: 22:28 | File Size: 31.2 MB

Episode Notes

In this special episode on Fish Oil—Facts, Fiction, and EPA our host, Dr. Neil Skolnik, will discuss the evidence distinguishing fish oil from Amarin (Icosapent ethyl). This special episode is supported by an independent educational grant from Amarin.

Presented by:

Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John Osborne, MD, PhD, Preventive cardiologist and lipidologist, Chief medical officer of Clear Cardio, LLC

Selected references:

Omega-3 Fatty Acids: STRENGTH trial - JAMA. 2020;324(22):2268-2280

Icosapent Ethyl: JELIS - Lancet. 2007;369(9567):1090-1098

Icosapent Ethyl: REDUCE-IT - N Engl J Med 2019; 380:11-22

ADA Standards of Care: Diabetes Care 2025;48(Supplement_1):S207–S238 https://doi.org/10.2337/dc25-S010

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: Circulation. 2023;148. doi: 10.1161/CIR.0000000000001168

Diabetes Core Update is a monthly audio podcast devoted to presenting and discussing the latest clinically relevant articles from ADA’s four scholarly journals: Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Users can freely access previous episodes of Diabetes Core Update here.

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