To assess the feasibility and efficacy of a novel use of continuous glucose monitoring (CGM) in prediabetes to promote behavioral change and improve glycemia.
We conducted a single-arm prospective study in a pediatric obesity clinic to evaluate the feasibility and acceptability of wearing a CGM sensor in children aged 10–17 years with obesity (BMI ≥95th percentile for age) and prediabetes. Feasibility was determined through participant recruitment. We analyzed differences in A1C, glucose variability, BMI, and dietary intake at 12 weeks.
Of 22 participants recruited, 14 completed the study. Over 12 weeks, the mean BMI percentage of the 95th percentile decreased from 153.4 to 150.1% (P = 0.006), daily estimated carbohydrate consumption decreased by 41.4% (P = 0.009), and A1C decreased by 0.2% (P = 0.03).
CGM in an adolescent population with prediabetes and obesity may be a helpful adjunct to therapy to improve A1C, support dietary changes, reduce the rate of weight gain, and attenuate diabetes risk.
