American Diabetes Association

TABLE 1

Association analysis of SNPs in the GAD2 region in a maximum of 472 diabetic multiplex families originating from the U.K.

Marker	Allele	Transmitted	Nontransmitted	P^*
−2,625 A>G	A	127	91	0.02
−1,937 C>T	C	242	230	0.6
−1,399 C>A	A	186	191	0.82
−243 A>G	A	175	167	0.69
84 A>G	A	145	136	0.64
2,414 C>A	A	12	17	0.43
7,882 G>A	A	11	13	0.67
12,669 A>G	A	114	76	0.01
12,689 C>A>T	A	80	108	0.04
	C	369	339	0.26
	T	376	378	0.95
12,750 T>G	G	77	117	0.01
29,208 C>T	C	100	78	0.11
53,842 G>C	C	134	169	0.05
83,897 T>A	A	172	200	0.2

Marker	Allele	Transmitted	Nontransmitted	P^*
−2,625 A>G	A	127	91	0.02
−1,937 C>T	C	242	230	0.6
−1,399 C>A	A	186	191	0.82
−243 A>G	A	175	167	0.69
84 A>G	A	145	136	0.64
2,414 C>A	A	12	17	0.43
7,882 G>A	A	11	13	0.67
12,669 A>G	A	114	76	0.01
12,689 C>A>T	A	80	108	0.04
	C	369	339	0.26
	T	376	378	0.95
12,750 T>G	G	77	117	0.01
29,208 C>T	C	100	78	0.11
53,842 G>C	C	134	169	0.05
83,897 T>A	A	172	200	0.2

Robust variance estimators were used in the calculation of P values to ensure a valid test of association.