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TABLE 2

Longitudinal analysis: subgroups categorized according to deciles of change in BCDI (adjusted) (Pima Indians, n = 187)

Increase in BCDI
Decrease in BCDI
P (ANOVA)
Highest decileLower nine decilesHighest decileLower nine deciles
n 88 83  
Change BCDI (log, adjusted*) 0.37 ± 0.02 0.13 ± 0.01 −0.40 ± 0.03 −0.13 ± 0.01 <0.0001 
Follow-up time (years) 4.8 ± 0.9 4.3 ± 0.3 4.7 ± 1.0 4.0 ± 0.3 0.8 
BCDI      
 Baseline 80 ± 17 113 ± 10 112 ± 35 114 ± 12 0.8 
 Follow-up 204 ± 20 152 ± 11 45 ± 9 78 ± 6 <0.0001 
DI      
 Baseline 722 ± 132 701 ± 41 704 ± 132 682 ± 43 1.0 
 Follow-up 100 ± 13 103 ± 7 112 ± 13 96 ± 6 0.8 
Fasting glucose (mg/dl)      
 Baseline 91 ± 2 90 ± 1 87 ± 2 90 ± 1 0.6 
 Follow-up 94 ± 2 90 ± 1 82 ± 2 88 ± 1 0.003 
2-h glucose (mg/dl)      
 Baseline 99 ± 7 110 ± 2 104 ± 7 110 ± 2 0.4 
 Follow-up 115 ± 5 114 ± 2 84 ± 6 110 ± 2 <0.001 
AIR (pmol/l)      
 Baseline 230 ± 42 269 ± 18 268 ± 62 265 ± 22 1.0 
 Follow-up 374 ± 33 316 ± 22 180 ± 25 214 ± 14 <0.001 
M (mg · kg EMBS−1 · min−1     
 Baseline 3.2 ± 0.4 2.8 ± 0.1 2.9 ± 0.4 2.9 ± 0.1 0.8 
 Follow-up 1.9 ± 0.1 2.2 ± 0.04 4.4 ± 0.3 3.0 ± 0.1 <0.0001 
Increase in BCDI
Decrease in BCDI
P (ANOVA)
Highest decileLower nine decilesHighest decileLower nine deciles
n 88 83  
Change BCDI (log, adjusted*) 0.37 ± 0.02 0.13 ± 0.01 −0.40 ± 0.03 −0.13 ± 0.01 <0.0001 
Follow-up time (years) 4.8 ± 0.9 4.3 ± 0.3 4.7 ± 1.0 4.0 ± 0.3 0.8 
BCDI      
 Baseline 80 ± 17 113 ± 10 112 ± 35 114 ± 12 0.8 
 Follow-up 204 ± 20 152 ± 11 45 ± 9 78 ± 6 <0.0001 
DI      
 Baseline 722 ± 132 701 ± 41 704 ± 132 682 ± 43 1.0 
 Follow-up 100 ± 13 103 ± 7 112 ± 13 96 ± 6 0.8 
Fasting glucose (mg/dl)      
 Baseline 91 ± 2 90 ± 1 87 ± 2 90 ± 1 0.6 
 Follow-up 94 ± 2 90 ± 1 82 ± 2 88 ± 1 0.003 
2-h glucose (mg/dl)      
 Baseline 99 ± 7 110 ± 2 104 ± 7 110 ± 2 0.4 
 Follow-up 115 ± 5 114 ± 2 84 ± 6 110 ± 2 <0.001 
AIR (pmol/l)      
 Baseline 230 ± 42 269 ± 18 268 ± 62 265 ± 22 1.0 
 Follow-up 374 ± 33 316 ± 22 180 ± 25 214 ± 14 <0.001 
M (mg · kg EMBS−1 · min−1     
 Baseline 3.2 ± 0.4 2.8 ± 0.1 2.9 ± 0.4 2.9 ± 0.1 0.8 
 Follow-up 1.9 ± 0.1 2.2 ± 0.04 4.4 ± 0.3 3.0 ± 0.1 <0.0001 

Data are mean ± SE.

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