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TABLE 1

Characterization of high salt–fed rats at 2 weeks of salt loading

ControlsHigh salt–fed ratsP
n 
Body weight (g) 246.9 ± 5.3 244.2 ± 5.6 0.37 
Systolic pressure (mmHg) 116.5 ± 2.2 132.5 ± 2.2 <0.001 
Diastolic pressure (mmHg) 57.4 ± 2.5 65.3 ± 3.9 0.11 
Heart rate (min–1373.6 ± 6.1 353.5 ± 10.1 0.10 
Food intake per rat (g/day) 24.4 ± 0.5 24.2 ± 0.6 NS 
Fasting blood glucose (mg/dl) 97.8 ± 2.5 108.5 ± 2.8 0.010 
Fasting plasma insulin (ng/dl) 0.61 ± 0.06 0.86 ± 0.07 0.026 
Total cholesterol (mg/dl) 69.3 ± 0.3 71.3 ± 3.4 0.58 
Triglyceride (mg/dl) 77.0 ± 2.1 46.7 ± 6.9 <0.05 
Plasma renin activity (ng · l–1 · h–113.2 ± 3.4 2.5 ± 1.1 <0.05 
Plasma aldosterone (pg/ml) 230 ± 20 72 ± 15 <0.001 
Plasma norepinephrine (pg/ml) 112.8 ± 7.5 113.8 ± 7.1 NS 
ControlsHigh salt–fed ratsP
n 
Body weight (g) 246.9 ± 5.3 244.2 ± 5.6 0.37 
Systolic pressure (mmHg) 116.5 ± 2.2 132.5 ± 2.2 <0.001 
Diastolic pressure (mmHg) 57.4 ± 2.5 65.3 ± 3.9 0.11 
Heart rate (min–1373.6 ± 6.1 353.5 ± 10.1 0.10 
Food intake per rat (g/day) 24.4 ± 0.5 24.2 ± 0.6 NS 
Fasting blood glucose (mg/dl) 97.8 ± 2.5 108.5 ± 2.8 0.010 
Fasting plasma insulin (ng/dl) 0.61 ± 0.06 0.86 ± 0.07 0.026 
Total cholesterol (mg/dl) 69.3 ± 0.3 71.3 ± 3.4 0.58 
Triglyceride (mg/dl) 77.0 ± 2.1 46.7 ± 6.9 <0.05 
Plasma renin activity (ng · l–1 · h–113.2 ± 3.4 2.5 ± 1.1 <0.05 
Plasma aldosterone (pg/ml) 230 ± 20 72 ± 15 <0.001 
Plasma norepinephrine (pg/ml) 112.8 ± 7.5 113.8 ± 7.1 NS 

Data are means ± SE.

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