Comparison between clinical and metabolic characteristics of type 2 diabetic patients positive (anti-CD38+) and negative (anti-CD38−) for anti-CD38 autoantibodies
| . | anti-CD38+ . | anti-CD38− . | P . |
|---|---|---|---|
| n | 19 | 95 | — |
| Sex (%) | |||
| Male | 52.6 | 60.0 | NS |
| Female | 47.4 | 40.0 | NS |
| Age (years) | 66.0 ± 8.0 | 63.4 ± 9.5 | NS |
| BMI (kg/m2) | 30.7 ± 6.2 | 28.1 ± 4.6 | 0.05 |
| Diabetes duration (years) | 11.4 ± 10.2 | 10.2 ± 7.3 | NS |
| Fasting plasma glucose (mmol/l) | 9.1 ± 3.0 | 9.2 ± 2.7 | NS |
| HbA1c (%) | 8.2 ± 1.6 | 8.4 ± 1.5 | NS |
| Fasting plasma C-peptide (ng/ml) | 2.31 ± 1.69 | 1.58 ± 0.88 | 0.04 |
| Fasting plasma insulin (μU/ml) | 21.46 ± 31.58 | 10.44 ± 6.91 | 0.03 |
| Therapy (%) | |||
| Diet alone | 21.1 | 9.5 | NS |
| Oral hypoglycemic agents | 68.4 | 64.2 | NS |
| Insulin alone or with oral hypoglycemic agents | 10.5 | 26.3 | NS |
| Autoimmune disease (%) | 0 | 3.2 | NS |
| Hypertension (%) | 88.2 | 79.1 | NS |
| . | anti-CD38+ . | anti-CD38− . | P . |
|---|---|---|---|
| n | 19 | 95 | — |
| Sex (%) | |||
| Male | 52.6 | 60.0 | NS |
| Female | 47.4 | 40.0 | NS |
| Age (years) | 66.0 ± 8.0 | 63.4 ± 9.5 | NS |
| BMI (kg/m2) | 30.7 ± 6.2 | 28.1 ± 4.6 | 0.05 |
| Diabetes duration (years) | 11.4 ± 10.2 | 10.2 ± 7.3 | NS |
| Fasting plasma glucose (mmol/l) | 9.1 ± 3.0 | 9.2 ± 2.7 | NS |
| HbA1c (%) | 8.2 ± 1.6 | 8.4 ± 1.5 | NS |
| Fasting plasma C-peptide (ng/ml) | 2.31 ± 1.69 | 1.58 ± 0.88 | 0.04 |
| Fasting plasma insulin (μU/ml) | 21.46 ± 31.58 | 10.44 ± 6.91 | 0.03 |
| Therapy (%) | |||
| Diet alone | 21.1 | 9.5 | NS |
| Oral hypoglycemic agents | 68.4 | 64.2 | NS |
| Insulin alone or with oral hypoglycemic agents | 10.5 | 26.3 | NS |
| Autoimmune disease (%) | 0 | 3.2 | NS |
| Hypertension (%) | 88.2 | 79.1 | NS |
Data are means ± SD unless otherwise indicated.