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TABLE 2

Prevalence of the Pro12→Ala polymorphism of PPAR-γ in type 2 diabetic individuals and control subjects

Type 2 diabetic subjectsNormal control subjects
n 2,201 1,212 
Genotype 
 Pro/Pro 2,097 1,114 
 Pro/Ala 103 96 
 Ala/Ala 
Ala allele frequency 2.39* (1.93–2.84) 4.13 (3.33–4.92) 
Type 2 diabetic subjectsNormal control subjects
n 2,201 1,212 
Genotype 
 Pro/Pro 2,097 1,114 
 Pro/Ala 103 96 
 Ala/Ala 
Ala allele frequency 2.39* (1.93–2.84) 4.13 (3.33–4.92) 

Data are n or % (95% CI).

*

OR for association of the Ala allele with type 2 diabetes is 0.57 (95% CI 0.43–0.75). χ2 = 16.3; P = 0.000054 vs. the normal control group.

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