SDF1 genotypes in 208 patients with type 1 diabetes according to age at disease onset
| . | Onset <15 years . | Onset ≥15 years . | P* . |
|---|---|---|---|
| n | 91 | 117 | |
| Genotype frequencies | |||
| G/G | 49 (53.8) | 88 (75.2) | |
| G/A | 37 (40.7) | 21 (17.9) | 0.0014† |
| A/A | 5 (5.5) | 8 (6.8) | |
| Allele frequencies‡ | |||
| G | 135 (74.2) | 197 (84.2) | 0.0137 |
| A | 47 (25.8) | 37 (15.8) | |
| Dominant model§ | |||
| A/A + A/G | 42 (46.2) | 29 (24.8) | 0.0019† |
| G/G | 49 (53.8) | 88 (75.2) |
| . | Onset <15 years . | Onset ≥15 years . | P* . |
|---|---|---|---|
| n | 91 | 117 | |
| Genotype frequencies | |||
| G/G | 49 (53.8) | 88 (75.2) | |
| G/A | 37 (40.7) | 21 (17.9) | 0.0014† |
| A/A | 5 (5.5) | 8 (6.8) | |
| Allele frequencies‡ | |||
| G | 135 (74.2) | 197 (84.2) | 0.0137 |
| A | 47 (25.8) | 37 (15.8) | |
| Dominant model§ | |||
| A/A + A/G | 42 (46.2) | 29 (24.8) | 0.0019† |
| G/G | 49 (53.8) | 88 (75.2) |
Data are n (%).
By contingency table analysis;
P < 0.02 after correction for multiple comparisons;
OR for the presence of the A allele = 1.85 (95% CI 1.14–3.00);
OR for the A phenotype = 2.6 (1.44–4.68).