American Diabetes Association

TABLE 4

Regression analyses for the changes of the S_i, the acute insulin response, the fasting insulin, and the 2-h insulin

	Regression coefficient	P value
Change in the S_i (n = 48)
Baseline weight	0.10	0.920
Age	0.37	0.847
Sex	−0.62	0.982
Study group^*	7.46	0.769
Weight change (%)^†	−8.10	<0.001
Change in AIR (mU · l⁻¹ · min⁻¹)	−0.15	0.077
Change in the acute insulin response (n = 48)
Baseline weight	0.23	0.730
Age	−1.07	0.408
Sex	0.22	0.990
Study group^*	−7.70	0.659
Weight change (%)^†	−3.22	0.083
Change in S_i (×10⁻⁴ · min⁻¹ · μU⁻¹ · ml⁻¹)	−10.02	0.254
Change in the fasting insulin (n = 66)
Baseline weight	−0.93	0.061
Age	−1.57	0.065
Sex	4.29	0.731
Study group^*	−10.26	0.388
Weight change (%)^†	5.01	<0.001
Change in the 2-h insulin (n = 47)
Baseline weight	−0.93	0.221
Age	0.24	0.853
Sex	−12.98	0.542
Study group^*	−8.01	0.679
Weight change (%)^†	3.89	0.012

	Regression coefficient	P value
Change in the S_i (n = 48)
Baseline weight	0.10	0.920
Age	0.37	0.847
Sex	−0.62	0.982
Study group^*	7.46	0.769
Weight change (%)^†	−8.10	<0.001
Change in AIR (mU · l⁻¹ · min⁻¹)	−0.15	0.077
Change in the acute insulin response (n = 48)
Baseline weight	0.23	0.730
Age	−1.07	0.408
Sex	0.22	0.990
Study group^*	−7.70	0.659
Weight change (%)^†	−3.22	0.083
Change in S_i (×10⁻⁴ · min⁻¹ · μU⁻¹ · ml⁻¹)	−10.02	0.254
Change in the fasting insulin (n = 66)
Baseline weight	−0.93	0.061
Age	−1.57	0.065
Sex	4.29	0.731
Study group^*	−10.26	0.388
Weight change (%)^†	5.01	<0.001
Change in the 2-h insulin (n = 47)
Baseline weight	−0.93	0.221
Age	0.24	0.853
Sex	−12.98	0.542
Study group^*	−8.01	0.679
Weight change (%)^†	3.89	0.012

Study groups were encoded as 1 = intervention group and 2 = control group.

†

Weight change was calculated as {[weight (kg)_{4 year} − weight (kg)_baseline]/[weight (kg)_baseline]} × 100.