Data are n (%) unless otherwise indicated. For all SNPs the more common allele is coded as “1” and the less common allele is coded as “2.” For the “dominant” model ORs are calculated comparing those homozygous or heterozygous for the common allele (11 or 12) with the odds for those homozygous for the less common allele (22). Similarly, the “recessive” model compares those homozygous for the common allele (11) with the others (12 or 22). In the additive model, the OR is calculated for each copy of the common allele. In the case-control study, P values are calculated by Fisher’s exact test, except for the additive model, for which the P value is calculated by the χ² test. For the subjects in the genome-wide linkage study, the ORs and P values are calculated by generalized estimating equations that adjust for age, sex, birth year, and ethnicity and that account for family membership (sibship). The dominant model is not analyzed in instances where there are too few individuals homozygous for the rare allele to obtain reliable estimates. The genotypes are presented as total numbers and their percent in parenthesis.