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TABLE 2

Cox proportional hazards models for prediction of all-cause mortality

Total population (n = 994)
No CHD (n = 742)
Possible or definite CHD (n = 252)
HR95% CIχ2PHR95% CIχ2PHR95% CIχ2P
Adjusted for study center only             
 STD ≥50 μV 4.68 3.12–7.01 55.9 <0.001 5.08 2.46–10.51 19.2 <0.001 2.98 1.77–5.02 16.9 <0.001 
 PCA ratio* 2.11 1.46–3.05 15.7 <0.001 1.44 0.77–2.70 1.3 0.259 1.88 1.15–3.09 6.2 0.013 
 QTc >460 ms 1.95 1.35–2.83 12.6 <0.001 1.90 1.16–3.12 6.4 0.011 1.82 1.05–3.17 4.5 0.033 
Adjusted for multiple covariates             
 STD ≥50 μV 2.36 1.38–4.02 9.8 0.002 2.87 1.05–1.12 4.2 0.040 1.95 1.01–3.76 3.9 0.047 
 PCA ratio* 1.33 0.82–2.13 1.3 0.246 1.08 0.49–2.38 0.1 0.848 1.44 0.80–2.59 1.5 0.221 
 QTc >460 ms 2.03 1.32–3.12 10.4 0.001 2.19 1.25–3.81 7.6 0.006 1.43 0.74–2.78 1.1 0.287 
Total population (n = 994)
No CHD (n = 742)
Possible or definite CHD (n = 252)
HR95% CIχ2PHR95% CIχ2PHR95% CIχ2P
Adjusted for study center only             
 STD ≥50 μV 4.68 3.12–7.01 55.9 <0.001 5.08 2.46–10.51 19.2 <0.001 2.98 1.77–5.02 16.9 <0.001 
 PCA ratio* 2.11 1.46–3.05 15.7 <0.001 1.44 0.77–2.70 1.3 0.259 1.88 1.15–3.09 6.2 0.013 
 QTc >460 ms 1.95 1.35–2.83 12.6 <0.001 1.90 1.16–3.12 6.4 0.011 1.82 1.05–3.17 4.5 0.033 
Adjusted for multiple covariates             
 STD ≥50 μV 2.36 1.38–4.02 9.8 0.002 2.87 1.05–1.12 4.2 0.040 1.95 1.01–3.76 3.9 0.047 
 PCA ratio* 1.33 0.82–2.13 1.3 0.246 1.08 0.49–2.38 0.1 0.848 1.44 0.80–2.59 1.5 0.221 
 QTc >460 ms 2.03 1.32–3.12 10.4 0.001 2.19 1.25–3.81 7.6 0.006 1.43 0.74–2.78 1.1 0.287 
*

>32.0% in women, >24.6% in men.

Cox model with all three ECG variables entered, adjusted for age, BMI, diastolic and systolic blood pressures, fasting glucose, GHb, HDL and LDL cholesterol levels, triglyceride level, albuminuria, alcohol use, history of smoking, and study center. Prevalent CHD was included as a covariate only in the total population. HR, hazard ratio.

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