Estimated parameters of the two-compartment minimal model before (pre) and after (16 h and 1 week) the training
. | Pre . | 16 h . | 1 week . |
---|---|---|---|
V1 (dt/kg) | 0.90 ± 0.04 | 1.13 ± 0.06* | 1.13 ± 0.05* |
k21 (min−1) | 0.1269 ± 0.0095 | 0.1083 ± 0.0136 | 0.1062 ± 0.0093 |
k12 (min−1) | 0.1387 ± 0.0186 | 0.1242 ± 0.0117 | 0.1212 ± 0.0085 |
k02 (min−1) | 0.00411 ± 0.00032 | 0.00444 ± 0.00051 | 0.00500 ± 0.00024 |
p2 (min−1) | 0.091 ± 0.015 | 0.088 ± 0.009 | 0.093 ± 0.007 |
sk (ml · μU−1 · min−1) | 0.00167 ± 0.00038 | 0.00244 ± 0.00061 | 0.00164 ± 0.00044 |
kp (min−1) | 0.0042 ± 0.0002 | 0.0041 ± 0.0002 | 0.0048 ± 0.0003 |
. | Pre . | 16 h . | 1 week . |
---|---|---|---|
V1 (dt/kg) | 0.90 ± 0.04 | 1.13 ± 0.06* | 1.13 ± 0.05* |
k21 (min−1) | 0.1269 ± 0.0095 | 0.1083 ± 0.0136 | 0.1062 ± 0.0093 |
k12 (min−1) | 0.1387 ± 0.0186 | 0.1242 ± 0.0117 | 0.1212 ± 0.0085 |
k02 (min−1) | 0.00411 ± 0.00032 | 0.00444 ± 0.00051 | 0.00500 ± 0.00024 |
p2 (min−1) | 0.091 ± 0.015 | 0.088 ± 0.009 | 0.093 ± 0.007 |
sk (ml · μU−1 · min−1) | 0.00167 ± 0.00038 | 0.00244 ± 0.00061 | 0.00164 ± 0.00044 |
kp (min−1) | 0.0042 ± 0.0002 | 0.0041 ± 0.0002 | 0.0048 ± 0.0003 |
Values are the means ± SE. V1, volume of the first compartment; k21, k12, and K02, glucose kinetic parameters; p2 and sk parameters describing insulin action; kp, proportional effect of glucose mass in the first compartment on glucose disposal from the same compartment.
P < 0.05 vs. before training.