Clinical and metabolic characteristics of obese subjects before and after a VLCD treatment
| . | VLCD . | . | |
|---|---|---|---|
| . | Pretreatment . | Posttreatment . | |
| n | 6 | 6 | |
| Age (years) | 45 ± 3 | 45 ± 3 | |
| Body weight (kg) | 95.0 ± 6.3 | 86.7 ± 6.0* | |
| BMI (kg/m2) | 34.5 ± 1.7 | 31.8 ± 2.2* | |
| Skinfold thickness (mm) | 206 ± 15 | 179 ± 13† | |
| HbA1c (%) | 5.5 ± 0.2 | 5.4 ± 0.1 | |
| Glucose (mmol/l) | 5.2 ± 0.1 | 5.0 ± 0.12 | |
| Insulin (pmol/l) | 96.0 ± 13.4 | 84 ± 7.8 | |
| Clamp insulin (pmol/l) | 6,931 ± 726 | 5,998 ± 693 | |
| Triglyceride (mg/dl) | 183 ± 51 | 115 ± 20 | |
| Free fatty acid (mmol/l) | 0.53 ± 0.08 | 0.52 ± 0.06 | |
| GDR (mg · kg−1 · min−1) | 8.2 ± 0.7 | 10.2 ± 1.3† | |
| . | VLCD . | . | |
|---|---|---|---|
| . | Pretreatment . | Posttreatment . | |
| n | 6 | 6 | |
| Age (years) | 45 ± 3 | 45 ± 3 | |
| Body weight (kg) | 95.0 ± 6.3 | 86.7 ± 6.0* | |
| BMI (kg/m2) | 34.5 ± 1.7 | 31.8 ± 2.2* | |
| Skinfold thickness (mm) | 206 ± 15 | 179 ± 13† | |
| HbA1c (%) | 5.5 ± 0.2 | 5.4 ± 0.1 | |
| Glucose (mmol/l) | 5.2 ± 0.1 | 5.0 ± 0.12 | |
| Insulin (pmol/l) | 96.0 ± 13.4 | 84 ± 7.8 | |
| Clamp insulin (pmol/l) | 6,931 ± 726 | 5,998 ± 693 | |
| Triglyceride (mg/dl) | 183 ± 51 | 115 ± 20 | |
| Free fatty acid (mmol/l) | 0.53 ± 0.08 | 0.52 ± 0.06 | |
| GDR (mg · kg−1 · min−1) | 8.2 ± 0.7 | 10.2 ± 1.3† | |
Data are means ± SD. Glucose, insulin, free fatty acid, and triglycerides were measured after an overnight fast. Skinfold thickness = abdominal + subscapular + suprailiac + chest.
P < 0.01 vs. pretreatment;
P < 0.05 vs. pretreatment.