TABLE 1

Pdi mRNA abundance in pancreatic islets of lean and obese B6 and BTBR mice

Pdi expressionLevelPlasma glucose(mg/dl)
 B6 BTBR B6 BTBR 
Lean mice 1.0 33.0 ± 2.7 ND ND 
6-week female ob/ob mice 2.1 ± 0.1 53.5 ± 5.4 163 166 
6-week male ob/ob mice 1.7 ± 0.3 52.8 ± 4.3 185 333 
14-week female ob/ob mice ND 42.4 ± 5.4 ND 289 
14-week male ob/ob mice 1.1 65.4 ± 1.8 149 539 
Pdi expressionLevelPlasma glucose(mg/dl)
 B6 BTBR B6 BTBR 
Lean mice 1.0 33.0 ± 2.7 ND ND 
6-week female ob/ob mice 2.1 ± 0.1 53.5 ± 5.4 163 166 
6-week male ob/ob mice 1.7 ± 0.3 52.8 ± 4.3 185 333 
14-week female ob/ob mice ND 42.4 ± 5.4 ND 289 
14-week male ob/ob mice 1.1 65.4 ± 1.8 149 539 

Data are means ± SE for those groups with at least two mice. The mRNA levels were measured by qRT-PCR and were normalized to those of the B6 lean mice, which was set at 1.0. There were 1–5 mice in each of the comparison groups. The average plasma glucose (mg/dl) for each comparison group is also listed for reference.

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