Pdi mRNA abundance in pancreatic islets of lean and obese B6 and BTBR mice
. | Pdi expression . | Level . | Plasma glucose . | (mg/dl) . |
---|---|---|---|---|
B6 | BTBR | B6 | BTBR | |
Lean mice | 1.0 | 33.0 ± 2.7 | ND | ND |
6-week female ob/ob mice | 2.1 ± 0.1 | 53.5 ± 5.4 | 163 | 166 |
6-week male ob/ob mice | 1.7 ± 0.3 | 52.8 ± 4.3 | 185 | 333 |
14-week female ob/ob mice | ND | 42.4 ± 5.4 | ND | 289 |
14-week male ob/ob mice | 1.1 | 65.4 ± 1.8 | 149 | 539 |
. | Pdi expression . | Level . | Plasma glucose . | (mg/dl) . |
---|---|---|---|---|
B6 | BTBR | B6 | BTBR | |
Lean mice | 1.0 | 33.0 ± 2.7 | ND | ND |
6-week female ob/ob mice | 2.1 ± 0.1 | 53.5 ± 5.4 | 163 | 166 |
6-week male ob/ob mice | 1.7 ± 0.3 | 52.8 ± 4.3 | 185 | 333 |
14-week female ob/ob mice | ND | 42.4 ± 5.4 | ND | 289 |
14-week male ob/ob mice | 1.1 | 65.4 ± 1.8 | 149 | 539 |
Data are means ± SE for those groups with at least two mice. The mRNA levels were measured by qRT-PCR and were normalized to those of the B6 lean mice, which was set at 1.0. There were 1–5 mice in each of the comparison groups. The average plasma glucose (mg/dl) for each comparison group is also listed for reference.