TABLE 2

Pdi mRNA abundance in various tissues of B6 and BTBR mice

Lean mice
ob/ob mice
B6BTBRB6BTBR
Muscle 2.7 ± 0.7 101.7 ± 6.7 8.2 ± 4.7 53.8 ± 4.3 
Adipose tissue 1.8 ± 0.4 40.0 ± 3.7 1.0 ± 0.2 41.9 ± 20.3 
Liver 8.9 ± 1.3 273.6 ± 24.6 14.6 ± 1.4 241.8 ± 54.4 
Pancreatic acinar ND ND 8.8 ± 3.1 223.5 ± 11.9 
Pancreatic islets 6.1 ± 1.3 52.1 ± 10.5 1.9 ± 0.2 58.8 ± 3.3 
Lean mice
ob/ob mice
B6BTBRB6BTBR
Muscle 2.7 ± 0.7 101.7 ± 6.7 8.2 ± 4.7 53.8 ± 4.3 
Adipose tissue 1.8 ± 0.4 40.0 ± 3.7 1.0 ± 0.2 41.9 ± 20.3 
Liver 8.9 ± 1.3 273.6 ± 24.6 14.6 ± 1.4 241.8 ± 54.4 
Pancreatic acinar ND ND 8.8 ± 3.1 223.5 ± 11.9 
Pancreatic islets 6.1 ± 1.3 52.1 ± 10.5 1.9 ± 0.2 58.8 ± 3.3 

Data are means ± SE. The mRNA levels were measured by qRT-PCR and were normalized to those in the adipose tissue of B6-ob/ob mice. There were 2–4 mice in each of the comparison groups.

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