Selected positional candidate genes within the support intervals of obesity and glucose level QTLs
| Chromosome . | Trait . | Marker(s) . | No. of Genes* . | ID . | Name . |
|---|---|---|---|---|---|
| 1 | Obesity | D1Mit187 {D1Mit10, D1Mit139, 8.4 cM} | 134 | Avpr1b | Vasopressin V1B receptor |
| Insig2 | Insulin-induced gene 2 | ||||
| Hdlbp | HDL binding protein | ||||
| Capn10 | Calpain 10 | ||||
| Pfkfb2 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | ||||
| Daf1 | Complement decay-accelerating factor, GPI-anchored precursor | ||||
| Dbi | Acyl-CoA-binding protein (ACBP) | ||||
| Tnfrsf11a | Tumor necrosis factor receptor superfamily member 11A precursor | ||||
| 8 | Obesity | D8Mit89 {D8Mit316, D8Mit13, 11 cM} | 69 | Trhr2 | Thyrotropin-releasing hormone receptor 2 |
| Mc1r | Melanocortin-1 receptor | ||||
| 10 | Obesity | D10Mit266 {D10Mit178, D10Mit103,11 cM} | 54 | Frs2 | Fibroblast growth-factor receptor substrate 2 |
| Avpr1a | Vasopressin V1A receptor | ||||
| Tph2 | Tryptophan 5-hydroxylase 2 | ||||
| X | Obesity | DXMit186 {DXMit121, DXMit186, 2 cM} | 34 | Grpr | Gastrin-releasing peptide receptor |
| Ace2 | ACE precursor 2 | ||||
| Tlr8 | Toll-like receptor 8 precursor | ||||
| Tlr7 | Toll-like receptor 7 precursor | ||||
| 6 | Glucose | D6Mit96 {D6Mit175, D6Mit186, 2 cM} | 38 | Fabp1 | Fatty acid–binding protein, liver |
| 19 | Glucose | D19Mit28 {D19Mit43, D19Mit16, 16 cM} | 37 | Stx3 | Syntaxin 3 |
| X | Glucose | DXMit173 {DXMit144, DXMit121, 47 cM} | 238 | Gpr50 | Melatonin-related receptor |
| Avpr2 | Arginine vasopressin receptor 2 | ||||
| G6pdx | Glucose-6-phosphate 1-dehydrogenase X | ||||
| Pgr15l | Neuropeptide Y receptor | ||||
| Gilz | Glucocorticoid-induced leucine zipper protein | ||||
| Irs4 | Insulin receptor substrate-4 | ||||
| Capn6 | Calpain 6 | ||||
| Mbtps2 | Mammalian sterol-regulatory element-binding protein (SREBP) site 2 protease |
| Chromosome . | Trait . | Marker(s) . | No. of Genes* . | ID . | Name . |
|---|---|---|---|---|---|
| 1 | Obesity | D1Mit187 {D1Mit10, D1Mit139, 8.4 cM} | 134 | Avpr1b | Vasopressin V1B receptor |
| Insig2 | Insulin-induced gene 2 | ||||
| Hdlbp | HDL binding protein | ||||
| Capn10 | Calpain 10 | ||||
| Pfkfb2 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | ||||
| Daf1 | Complement decay-accelerating factor, GPI-anchored precursor | ||||
| Dbi | Acyl-CoA-binding protein (ACBP) | ||||
| Tnfrsf11a | Tumor necrosis factor receptor superfamily member 11A precursor | ||||
| 8 | Obesity | D8Mit89 {D8Mit316, D8Mit13, 11 cM} | 69 | Trhr2 | Thyrotropin-releasing hormone receptor 2 |
| Mc1r | Melanocortin-1 receptor | ||||
| 10 | Obesity | D10Mit266 {D10Mit178, D10Mit103,11 cM} | 54 | Frs2 | Fibroblast growth-factor receptor substrate 2 |
| Avpr1a | Vasopressin V1A receptor | ||||
| Tph2 | Tryptophan 5-hydroxylase 2 | ||||
| X | Obesity | DXMit186 {DXMit121, DXMit186, 2 cM} | 34 | Grpr | Gastrin-releasing peptide receptor |
| Ace2 | ACE precursor 2 | ||||
| Tlr8 | Toll-like receptor 8 precursor | ||||
| Tlr7 | Toll-like receptor 7 precursor | ||||
| 6 | Glucose | D6Mit96 {D6Mit175, D6Mit186, 2 cM} | 38 | Fabp1 | Fatty acid–binding protein, liver |
| 19 | Glucose | D19Mit28 {D19Mit43, D19Mit16, 16 cM} | 37 | Stx3 | Syntaxin 3 |
| X | Glucose | DXMit173 {DXMit144, DXMit121, 47 cM} | 238 | Gpr50 | Melatonin-related receptor |
| Avpr2 | Arginine vasopressin receptor 2 | ||||
| G6pdx | Glucose-6-phosphate 1-dehydrogenase X | ||||
| Pgr15l | Neuropeptide Y receptor | ||||
| Gilz | Glucocorticoid-induced leucine zipper protein | ||||
| Irs4 | Insulin receptor substrate-4 | ||||
| Capn6 | Calpain 6 | ||||
| Mbtps2 | Mammalian sterol-regulatory element-binding protein (SREBP) site 2 protease |
Support interval marker boundaries and length are given inside brackets { }.
Number of known genes within the support interval.