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TABLE 1

Results of QTL analysis of selected genotyping data

ChromosomeMarkerTrait, diet, durationLOD scorePhenotypic variation (%)Donor strain
D3Mit278 Hyperinsulinemia, low-fat diet, week 12 3.2* 29 B6 
D3Mit127 Hyperleptinemia, low-fat diet, week 12 2.7* 78 B6 
10 D10Mit162 Hyperleptinemia, high-fat diet, week 2 2.9* 28 129 
11 D11Mit199 Hyperinsulinemia, high-fat diet, week 6 3.0* 30 B6 
12 D12Mit231 Hyperleptinemia, low-fat diet, week 2 3.2* 25 129 
14 D14Mit52 Hyperinsulinemia, low-fat diet, week 18 3.0* 25 B6 
14 D14Mit192 Increased weight gain, low-fat diet, week 18 3.0* 52 B6 
  Hyperglycemia, high-fat diet, week 12 3.3* 33 B6 
15 D15Mit13 Fasting hyperglycemia, low-fat diet, week 19 3.3 49 B6 
ChromosomeMarkerTrait, diet, durationLOD scorePhenotypic variation (%)Donor strain
D3Mit278 Hyperinsulinemia, low-fat diet, week 12 3.2* 29 B6 
D3Mit127 Hyperleptinemia, low-fat diet, week 12 2.7* 78 B6 
10 D10Mit162 Hyperleptinemia, high-fat diet, week 2 2.9* 28 129 
11 D11Mit199 Hyperinsulinemia, high-fat diet, week 6 3.0* 30 B6 
12 D12Mit231 Hyperleptinemia, low-fat diet, week 2 3.2* 25 129 
14 D14Mit52 Hyperinsulinemia, low-fat diet, week 18 3.0* 25 B6 
14 D14Mit192 Increased weight gain, low-fat diet, week 18 3.0* 52 B6 
  Hyperglycemia, high-fat diet, week 12 3.3* 33 B6 
15 D15Mit13 Fasting hyperglycemia, low-fat diet, week 19 3.3 49 B6 

Genotyping data were analyzed using MapMaker/QTL and MapManager. The indicated markers denote the marker closets to the peak. The LOD score values are according to MapMaker.

*

Significant LRS value and

suggestive significant LRS value according to MapManager. Phenotypic variation indicates the percentage of the phenotypic variation of the trait that can be explained by the locus.

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