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TABLE 1

Characteristics of the study cohort examined by a hyperglycemic clamp

nBMI (kg/m2)Fasting glucose (mmol/l)HbA1c (%)First-phase insulin (pmol/l)*Second-phase insulin (pmol/l)
Noncarriers 90 28.4 6.56 5.7 694 312 
A3243G carriers 24.7 6.35 5.9 390 141 
nBMI (kg/m2)Fasting glucose (mmol/l)HbA1c (%)First-phase insulin (pmol/l)*Second-phase insulin (pmol/l)
Noncarriers 90 28.4 6.56 5.7 694 312 
A3243G carriers 24.7 6.35 5.9 390 141 
*

First-phase integrated insulin concentrations at 2.5, 5, 7, and 10 min after application of 10 mmol/l hyperglycemia.

Second-phase average insulin concentration in the 120- to 180-min range, minus basal.

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