Characteristics of the study cohort examined by a hyperglycemic clamp
. | n . | BMI (kg/m2) . | Fasting glucose (mmol/l) . | HbA1c (%) . | First-phase insulin (pmol/l)* . | Second-phase insulin (pmol/l)† . |
---|---|---|---|---|---|---|
Noncarriers | 90 | 28.4 | 6.56 | 5.7 | 694 | 312 |
A3243G carriers | 2 | 24.7 | 6.35 | 5.9 | 390 | 141 |
. | n . | BMI (kg/m2) . | Fasting glucose (mmol/l) . | HbA1c (%) . | First-phase insulin (pmol/l)* . | Second-phase insulin (pmol/l)† . |
---|---|---|---|---|---|---|
Noncarriers | 90 | 28.4 | 6.56 | 5.7 | 694 | 312 |
A3243G carriers | 2 | 24.7 | 6.35 | 5.9 | 390 | 141 |
First-phase integrated insulin concentrations at 2.5, 5, 7, and 10 min after application of 10 mmol/l hyperglycemia.
Second-phase average insulin concentration in the 120- to 180-min range, minus basal.