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TABLE 2

Comparison of genotypic and allelic distributions of gene polymorphisms between type 2 diabetic patients and nondiabetic subjects

PolymorphismsGenotypes
Alleles
−226A>G A/A A/G G/G   
    Type 2 diabetes 106 (42.4) 110 (44.0) 34 (13.6) P = 0.032 322 (64.4) 178 (35.6) P = 0.007 
    Nondiabetic 136 (53.5) 95 (37.4) 23 (9.1)  367 (72.2) 141 (27.8)  
−233G>C G/G G/C C/C   
    Type 2 diabetes 240 (96.0) 10 (4.0) 0 (0) P = 0.439 490 (98.0) 10 (2.0) P = 0.419 
    Nondiabetic 247 (97.2) 7 (2.8) 0 (0)  501 (98.6) 7 (1.4)  
−279C>A C/C C/A A/A   
    Type 2 diabetes 215 (86.0) 35 (14.0) 0 (0) P = 0.643 465 (93.0) 35 (7.0) P = 0.655 
    Nondiabetic 222 (87.4) 32 (12.6) 0 (0)  476 (93.7) 32 (6.3)  
PolymorphismsGenotypes
Alleles
−226A>G A/A A/G G/G   
    Type 2 diabetes 106 (42.4) 110 (44.0) 34 (13.6) P = 0.032 322 (64.4) 178 (35.6) P = 0.007 
    Nondiabetic 136 (53.5) 95 (37.4) 23 (9.1)  367 (72.2) 141 (27.8)  
−233G>C G/G G/C C/C   
    Type 2 diabetes 240 (96.0) 10 (4.0) 0 (0) P = 0.439 490 (98.0) 10 (2.0) P = 0.419 
    Nondiabetic 247 (97.2) 7 (2.8) 0 (0)  501 (98.6) 7 (1.4)  
−279C>A C/C C/A A/A   
    Type 2 diabetes 215 (86.0) 35 (14.0) 0 (0) P = 0.643 465 (93.0) 35 (7.0) P = 0.655 
    Nondiabetic 222 (87.4) 32 (12.6) 0 (0)  476 (93.7) 32 (6.3)  

Data are n (%). The results of −2159A>G, −1449G>A, and −1388C>T are not shown because the −2159G, −1449A, and −1388T alleles are in complete linkage disequilibrium with the −226G allele.

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