Clinical characteristics and biochemical data of type 2 diabetic patients classified according to their genotypes of the −226A>G polymorphism
. | −226A >G genotype . | . | . | P . | ||
---|---|---|---|---|---|---|
. | G/G . | G/A . | A/A . | . | ||
n (male/female) | 34 (16/18) | 110 (58/52) | 106 (61/44) | 0.488 | ||
Age (years) | 62.4 ± 2.0 | 64.3 ± 1.1 | 62.2 ± 1.1 | 0.377 | ||
Age at diagnosis (years) | 45.6 ± 1.5 | 45.4 ± 0.9 | 45.6 ± 1.0 | 0.976 | ||
Duration of diabetes (years) | 16.7 ± 1.8 | 18.6 ± 1.0 | 16.4 ± 1.0 | 0.265 | ||
Maximum BMI (kg/m2) | 27.0 ± 0.6 | 26.5 ± 0.3 | 27.0 ± 0.3 | 0.554 | ||
BMI (kg/m2) | 23.4 ± 0.5 | 23.3 ± 0.3 | 23.7 ± 0.3 | 0.662 | ||
A1C (%) | 7.7 ± 0.2 | 7.5 ± 0.1 | 7.2 ± 0.1 | 0.072 | ||
Mode of treatment (D/OHA/Ins) (n) | 6/11/17 | 18/47/45 | 23/44/39 | |||
Insulin (%) | 50.0 | 40.9 | 37.7 | 0.389 |
. | −226A >G genotype . | . | . | P . | ||
---|---|---|---|---|---|---|
. | G/G . | G/A . | A/A . | . | ||
n (male/female) | 34 (16/18) | 110 (58/52) | 106 (61/44) | 0.488 | ||
Age (years) | 62.4 ± 2.0 | 64.3 ± 1.1 | 62.2 ± 1.1 | 0.377 | ||
Age at diagnosis (years) | 45.6 ± 1.5 | 45.4 ± 0.9 | 45.6 ± 1.0 | 0.976 | ||
Duration of diabetes (years) | 16.7 ± 1.8 | 18.6 ± 1.0 | 16.4 ± 1.0 | 0.265 | ||
Maximum BMI (kg/m2) | 27.0 ± 0.6 | 26.5 ± 0.3 | 27.0 ± 0.3 | 0.554 | ||
BMI (kg/m2) | 23.4 ± 0.5 | 23.3 ± 0.3 | 23.7 ± 0.3 | 0.662 | ||
A1C (%) | 7.7 ± 0.2 | 7.5 ± 0.1 | 7.2 ± 0.1 | 0.072 | ||
Mode of treatment (D/OHA/Ins) (n) | 6/11/17 | 18/47/45 | 23/44/39 | |||
Insulin (%) | 50.0 | 40.9 | 37.7 | 0.389 |
Data are shown as means ± SE unless otherwise indicated. P values are compared by one-way ANOVA or χ2 test for existence of insulin treatment. D, diet; Ins, insulin; OHA, oral hypoglycemic agents.