Demographic and metabolic variables in all subjects and subdivided based on the presence or absence of the metabolic syndrome
| . | All . | Metabolic syndrome yes . | Metabolic syndrome no . | P value* (metabolic syndrome yes vesus no) . |
|---|---|---|---|---|
| n (% male)† | 921 (51) | 803 (49) | 118 (66) | <0.0001 |
| Age (years) | 55.3 ± 0.3 | 55.6 ± 0.4 | 52.9 ± 1.0 | 0.011 |
| GAD positive (%) | 43 (4.7) | 32 (4.0) | 11 (9.3) | 0.011 |
| BMI (kg/m2) | 33.7 ± 0.2 | 34.5 ± 0.2 | 28.1 ± 0.5 | <0.0001 |
| Waist circumference (cm) | 108 ± 0.5 | 110 ± 0.5 | 93 ± 1.2 | N/A |
| Systolic blood pressure (mmHg) | 129 ± 0.5 | 131 ± 0.5 | 119 ± 1.3 | N/A |
| Diastolic blood pressure (mmHg) | 79 ± 0.3 | 79 ± 0.3 | 75 ± 0.8 | N/A |
| Fasting plasma glucose (mmol/l) | 8.4 ± 0.05 | 8.4 ± 0.05 | 8.3 ± 0.14 | N/A |
| A1C (%) | 7.5 ± 0.03 | 7.5 ± 0.03 | 7.6 ± 0.10 | 0.079 |
| HOMA-IR (μU/ml per mmol/l) * | 3.4 (3.2–3.5) | 3.6 (3.5–3.8) | 2.0 (1.8–2.3) | <0.0001 |
| Non-HDL cholesterol (mmol/l) * | 3.8 (3.8–3.9) | 3.9 (3.8–4.0) | 3.6 (3.4–3.8) | 0.003 |
| LDL cholesterol (mmol/l) * | 2.9 (2.8–2.9) | 2.8 (2.8–2.9) | 3.0 (2.8–3.2) | 0.037 |
| HDL cholesterol (mmol/l) * | 1.1 (1.1–1.1) | 1.1 (1.1–1.1) | 1.3 (1.3–1.4) | N/A |
| Triglycerides (mmol/l) * | 1.9 (1.9–2.0) | 2.1 (2.0–2.2) | 1.1 (1.0–1.2) | N/A |
| . | All . | Metabolic syndrome yes . | Metabolic syndrome no . | P value* (metabolic syndrome yes vesus no) . |
|---|---|---|---|---|
| n (% male)† | 921 (51) | 803 (49) | 118 (66) | <0.0001 |
| Age (years) | 55.3 ± 0.3 | 55.6 ± 0.4 | 52.9 ± 1.0 | 0.011 |
| GAD positive (%) | 43 (4.7) | 32 (4.0) | 11 (9.3) | 0.011 |
| BMI (kg/m2) | 33.7 ± 0.2 | 34.5 ± 0.2 | 28.1 ± 0.5 | <0.0001 |
| Waist circumference (cm) | 108 ± 0.5 | 110 ± 0.5 | 93 ± 1.2 | N/A |
| Systolic blood pressure (mmHg) | 129 ± 0.5 | 131 ± 0.5 | 119 ± 1.3 | N/A |
| Diastolic blood pressure (mmHg) | 79 ± 0.3 | 79 ± 0.3 | 75 ± 0.8 | N/A |
| Fasting plasma glucose (mmol/l) | 8.4 ± 0.05 | 8.4 ± 0.05 | 8.3 ± 0.14 | N/A |
| A1C (%) | 7.5 ± 0.03 | 7.5 ± 0.03 | 7.6 ± 0.10 | 0.079 |
| HOMA-IR (μU/ml per mmol/l) * | 3.4 (3.2–3.5) | 3.6 (3.5–3.8) | 2.0 (1.8–2.3) | <0.0001 |
| Non-HDL cholesterol (mmol/l) * | 3.8 (3.8–3.9) | 3.9 (3.8–4.0) | 3.6 (3.4–3.8) | 0.003 |
| LDL cholesterol (mmol/l) * | 2.9 (2.8–2.9) | 2.8 (2.8–2.9) | 3.0 (2.8–3.2) | 0.037 |
| HDL cholesterol (mmol/l) * | 1.1 (1.1–1.1) | 1.1 (1.1–1.1) | 1.3 (1.3–1.4) | N/A |
| Triglycerides (mmol/l) * | 1.9 (1.9–2.0) | 2.1 (2.0–2.2) | 1.1 (1.0–1.2) | N/A |
Data are means ± SE, n (%), or geometric means (95% CI).
P value based on Wilcoxon’s rank-sum test for continuum variables and χ2 test for dichotomous variables.
Nine patients did not have adequate data to assign metabolic syndrome category. N/A, not determined as used to categorize metabolic syndrome yes/no.