Conversion to type 2 diabetes (%) in all subjects and in men and women according to four SNPs of PPARD
| . | rs6902123* . | . | . | rs2267668 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | TT . | TC + CC . | P† . | AA . | AG + GG . | P† . | ||||
| n | 667 | 95 + 7 | 544 | 205 + 20 | ||||||
| All subjects | 39.5 | 46.1 | 0.207 | 40.0 | 41.5 | 0.690 | ||||
| Men | 42.6 | 35.7 | 0.337 | 38.7 | 47.9 | 0.091 | ||||
| Women | 36.5 | 58.7 | 0.004‡ | 41.2 | 34.3 | 0.220 | ||||
| . | rs6902123* . | . | . | rs2267668 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | TT . | TC + CC . | P† . | AA . | AG + GG . | P† . | ||||
| n | 667 | 95 + 7 | 544 | 205 + 20 | ||||||
| All subjects | 39.5 | 46.1 | 0.207 | 40.0 | 41.5 | 0.690 | ||||
| Men | 42.6 | 35.7 | 0.337 | 38.7 | 47.9 | 0.091 | ||||
| Women | 36.5 | 58.7 | 0.004‡ | 41.2 | 34.3 | 0.220 | ||||
| . | rs2016520 . | . | . | rs3734254 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | TT . | TC + CC . | P† . | TT . | TC + CC . | P† . | ||||
| n | 524 | 219 + 26 | 518 | 217 + 34 | ||||||
| All subjects | 39.9 | 41.2 | 0.724 | 38.0 | 45.0 | 0.064 | ||||
| Men | 39.6 | 45.0 | 0.305 | 39.1 | 45.7 | 0.211 | ||||
| Women | 40.1 | 36.8 | 0.544 | 37.0 | 44.2 | 0.187 | ||||
| . | rs2016520 . | . | . | rs3734254 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | TT . | TC + CC . | P† . | TT . | TC + CC . | P† . | ||||
| n | 524 | 219 + 26 | 518 | 217 + 34 | ||||||
| All subjects | 39.9 | 41.2 | 0.724 | 38.0 | 45.0 | 0.064 | ||||
| Men | 39.6 | 45.0 | 0.305 | 39.1 | 45.7 | 0.211 | ||||
| Women | 40.1 | 36.8 | 0.544 | 37.0 | 44.2 | 0.187 | ||||
P value for the interaction with sex = 0.008.
P value compares the conversion to diabetes between the two genotype groups (Fisher’s exact test).
Statistically significant.